Category: Ulcerative Colitis

Best Herbal Alternatives to Mesalamine for Ulcerative Colitis Treatment

Abstract

Ulcerative colitis is a chronic relapsing inflammatory bowel disease. It is an inflammation of the large intestine specifically in the colon. It causes ulcers and inflammation in the intestines. This disease mostly affects the innermost lining of the intestines. But it can also affect the whole length of the colon. This inflammation produces tiny sores which is called ulcers and spreads upward direction also. This further causes your bowel to move rapidly and empty frequently. Ulcer causes bleeding and discharge of mucus through anal region. It is an autoimmune disorder and affects people of all ages. The most common drug used in the treatment of UC is mesalamine, but this drug has many side effects also. So in this article we are going to discuss mesalamine and its alternative in Ayurveda.

Introduction

Mesalamine is an Anti-inflammatory drug. It is the active component of sulfasalazine. This drug probably inhibits prostaglandins and leukotriene synthesis. Mesalamine is the official name given to 5-ASA (aminosalicylic acid). 5-ASA is the active moiety in ulcerative colitis, but this drug is not effective orally. So it has been coated with pH sensitive acrylic polymer. This coated formulation delivers 5-ASA to the small intestine and colon.

ulcerative colitis causes

Pharmacokinetic

Mesalamine is not absorbed orally until it is coated with acrylic polymer. It is metabolized in the liver and excreted from urine. Its half-life is 0.5-10 hour. The action of this medicine is hampered in the patient who is suffering from renal diseases.

Dosage

2.4 gm dose has been found in the improvement of the symptoms of ulcerative colitis. Mesacol (Mesalamine) is available in following formulations and doses:

  1. Mesacol 400 mg
  2. Mesacol 800 mg
  3. Mesacol 1.2 grams
  4. Mesacol enema 4 g/60 ml.

Adverse effects

  • Nausea
  • Abdominal pain
  • Headache
  • Fever
  • Fatigue
  • Flatulence
  • Dizziness
  • Acne
  • Nephrotoxicity

Contraindications

It is contraindicated in

  • Hepatic and renal impairment
  • It should not be taken with glucocorticoids and sulfonylureas as it causes gastric toxicity and also increases the hypoglycemic action of sulfonylureas.
  • Also there are interactions with furosemide, spironolactone, methotrexate and rifampicin.

Uses

  • Ulcerative colitis
  • Crohn’s disease

The physician advised the patient that he/she had to live on the medicine for lifelong. Only dose adjustment is there either in lower dosage or higher dosage as per the patient symptoms. Long term use of this medicine causes hepatic and renal impairment.

Alternatives in Ayurveda

Ayurveda is the oldest holistic science. It treats various acute and even chronic diseases. This science treats the disease from its root cause. It provides two best formulations which are good alternatives to mesalamine. These two formulations include Kutaj ghan Vati and Vatsakadi Churna. These two herbal formulations have proven better for ulcerative colitis disease. This Ayurvedic medicine is much more effective than mesalamine and doesn’t cause any side effects as mesalamine does.

herbal supplements for ulcerative colitis

herbal supplements for ulcerative colitis1. Kutaj ghan vati

  1. This is a classical Ayurvedic formulation. It is made from the standardized extracts of Kutaj (Holarrhena antidysenterica). This herb is used in treating acute or chronic diarrhea. As the name suggests dysenterica it is mainly used in diarrhea, dysentery. This is the best herbal supplement for ulcerative colitis. Severe forms of diarrhea, dysentery, bleeding can be cured with the regular use of kutaj ghan vati. This provides proper functioning to the intestines. It provides complete relief from the symptoms of inflammatory bowel disease.

Chemical composition

Seeds of kutaj contain five main alkaloids

  • Conessine
  • Isoconessimine
  • Conessimin
  • Conarrhimin
  • Conimin

These alkaloids have antidysenteric and anthelmintic properties

Ayurvedic properties of Kutaj (Raspanchak)1

1. Ras (taste) – tikta (Bitter), kshaya (Astringent)

These two tastes help in pacifying pitta dosha and helps in stoppage of bleeding from stools.

2. Guna (properties) – Laghu (light), Ruksha (dry)

These properties help in balancing the vata dosha and stop the spread of this disease. This herb is easy to digest

3. Virya (potency) – Sheet (Cold)

This cool potency is helpful in ulcers and bleeding condition

4. Vipaka (post digestion effect) – katu (Pungent)

This pungent property helps in digestion and provides anti-inflammatory action

5. Karma (uses)

Piles, diarrhea, dysentery, mucus, skin disorders

2. Vatsakadi Churna

This is an Ayurvedic classical formulation. It provides strength to the digestive system naturally. It contains Kutaj (Holarrhena antidysenterica) and Bilva (Aegle marmelos). These two herbs are very beneficial in digestive disorders. This formulation is best to check diarrhea, gas formation and irregular bowel movements.

This formulation is used in treating mucus formation

1. Ras (taste) – tikta (Bitter), kshaya (Astringent)

Helps in stoppage of bleeding from stools and mucus.

2. Guna (properties) – Laghu (light), Ruksha (dry)

It is easily to digest and treat ulcers

3. Virya (potency) – ushna (hot)

It is helpful in improving digestion

4. Vipaka (post digestion effect) – katu (Pungent)

It improves digestion and stimulates digestive fire

5. Karma (uses)

Piles, diarrhea, dysentery, mucus

Conclusion

As mentioned above in the article mesalamine is having many side effects that leave very serious impacts on the body especially on our immune system. Our immune system is responsible for protecting our body from various kinds of infection and disorders and any impairment in our immune system can lead a person towards drastic conditions. So it’s better to use Ayurveda treatment because it does not cause any side effects and also treats the disease from its root. So above mentioned two best herbal formulations are effective in inflammatory bowel disease.

References

  1. Bhavprakash nighantu, Guduchyadi varga/118

Got Ulcerative Colitis?-Heal It With Ayurveda

Abstract

The Digestive system consists of the gastrointestinal tract which is the hollow organ joined in a long and twisting tube from mouth to the anus. This system helps in the digestion and assimilation of nutrients, to maintain the proper functioning of the body. The intestines play a major role in absorptions of the nutrients from the food, which is divided into two parts small intestine and large intestine. But in this modern world, unhealthy eating is common which causes various problems and hinders the normal functions of intestine and develops various health issues and Ulcerative Colitis is one among them. Ulcerative colitis is an inflammation of the colon which causes various symptoms like diarrhea, bleeding per rectum, abdominal pain, etc. But if you make some changes in the diet along with some natural remedies which are totally safe, then this complicated disease can be treated.

Ulcerative Colitis Treatment

Introduction

Ulcerative colitis is a disorder of the Large intestine. The large intestine is a lower gastrointestinal tract which includes: appendix, caecum, colon, rectum, and anus. The large intestine is about 5 feet long that absorbs water and even the remaining nutrients which were passed from the small intestine. Thus, this large intestine changes the waste from liquid to solid called stool.

Ulcerative colitis is a chronic or enduring disease that is characterized by inflammation of the colon that creates tiny sores known as ulcers. This inflammation causes rapid bowel movements and empties the bowel frequently along with this it causes bleeding, discharge of mucus and pus.

Ayurvedic Aspect Of Ulcerative Colitis

Ayurveda is an ancient form of medicine. Ayurveda word stands for the life of science. Ayurveda believes in the concept of three Dosha Vata, Pitta and Kapha. When these three dosha are balanced it attributes the healthy state of body and any imbalance in these causes various problems. An increase in Pitta Dosha with varying Vata causes Ulcerative Colitis. Ulcerative colitis is known as Pittaj Grahani. Consuming Pitta aggravating foods and following the lifestyle which damages particularly mamsa and rakta dhatu in the intestines forms ulcers hence hinders normal functions of the intestine. Moreover, the vitiated Vata dosha blocks the channels of Pitta and Kapha dosha and causes inflammation, pain and mucous

Types of Ulcerative Colitis

There are Five Types of Ulcerative Colitis

Ulcerative Proctitis

This type of ulcerative colitis affects the end of the colon. The inflammation of the colon causes symptoms like rectal bleeding and rectal pain. This is usually a mild type of ulcerative colitis.

Procto Sigmoiditis

This type involves the rectum and sigmoid colon. The inflammation of the rectum and sigmoid colon causes various symptoms like; abdominal cramp, pain, diarrhea and constant urge to pass stool.

Left-sided Colitis

This type affects the rectum and life side of the sigmoid, descending colon and rectum, which causes pain in the left side of the abdomen, bloody diarrhea, abdominal cramping, etc.

Pancolitis

This type affects the entire colon and can cause sometimes severe bloody diarrhea, abdominal pain, fatigue, and weight loss.

Acute severe ulcerative Colitis

It is a rare form of colitis that affects the whole colon cause’s severe pain, bleeding, inability to eat and diarrhea.

Causes of Ulcerative Colitis

There are Various Causes of Ulcerative Colitis

Genes

 A family history with ulcerative colitis will increase the chances in a new generation.

Environmental Factors

Eating certain food with high-fat content, stress and emotional distress causes ulcerative colitis. Some medications like anti-inflammatory, antibiotic, oral contraceptives can cause Ulcerative Colitis

Overactive Intestinal Immunity

Our Immune system will respond against bacteria, viruses, and other foreign bodies but due to autoimmune condition it will start affecting the healthy cells and causes inflammation.

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Symptoms of Ulcerative Colitis

There are Various Symptoms Which Depends on The Severity of Inflammations

  • Urgency to defecate
  • Abdominal pain
  • Diarrhea sometimes with blood and mucous
  • Inability to defecate i.e. constipation
  • Weight loss
  • Fever
  • Fatigue
  • Failure in growth in children

There are Various Complications like

  • A hole in the colon
  • Liver disease
  • Severe anemia
  • Bone loss
  • Severe dehydration

Herbal Remedies for Ulcerative Treatment by Planet Ayurveda

Ayurvedic Medicines for Ulcerative Colitis
Treatment of Ulcerative ColitisAyurveda believes in treating people with natural herbs which are pure, safe and have properties to balance three Dosha. Planet Ayurveda provides safe and effective Herbal Remedies for Ulcerative Colitis. These remedies are derived from natural herbs which are prepared according to the principle of Ayurveda. Combinations of herbs are made to balance the Dosha. These herbs also provide nourishment to the body.

For ulcerative colitis, Planet Ayurveda provides Ulcerative Colitis Care Pack which effectively tackles ulcerative colitis.

Ulcerative Colitis Care Pack

  1. Arjuna Capsules
  2. Vatsakadi Churna
  3. Pitta balance
  4. Kutaj Ghan Vati
  5. Arjuna Capsule

1. Arjuna Capsules

Arjuna (Terminalia Arjuna) is the most famous herb to heal ulcers due to its astringent property. Arjuna helps in detoxifying the blood and balance the Pitta and Kapha dosha thus, helps in controls the intestinal bleeding.

Dose: 2 Capsules twice daily with plain water after meals.

2. Vatsakadi Churna

It is a blend of various herbs like Saunf (Foeniculum vulgare), Bilva (Aegle marmelos), Dhania (Coriandrum sativum), Anar (Punica granatum), etc. It is a very effective remedy in ulcerative colitis. It helps in treating symptoms like diarrhea, and mucous. This remedy improves the tone of intestines and helps in regulating intestine movements and decrease the formation of gas.

Dose: 1 teaspoonful twice daily with plain water after a meal or boil this powder- 1 teaspoonful in 400ml water, keep it boiling till it remains only 50 ml. strain it and drink it. Twice daily. Prepare fresh every time.

3. Pitta Balance

Pitta balance is prepared by a combination of various calcium-rich herbs like Praval pishti (Coral Calcium), Jahar mohra pishti (an Ayurvedic Calcium compound), Mukta pishti (Pearl calcium), etc. Digestion problems like acidity, ulcers, piles, ulcerative colitis, etc. are caused by Pitta Dosha. Pitta balance helps to balance this Pitta dosha. Moreover, it stops the inflammatory process and helps to control bleeding.

Dose: 1 Capsule twice daily with plain water after meals

4. Kutaj Ghan Vati

Kutaz (Holarrhena antidysenterica) is a great herb that helps to control the frequency of motions and is an effective remedy in case of ulcerative colitis. It also improves the absorption of the nutrients in the gut by restoring the intestinal motility.

Dose: 2 Tablets twice daily with plain water after meals.

Home Remedies for Ulcerative Treatment

Making some dietary changes can help you to heal the ulcers and relieves the symptoms. There are numbers of food which help to soothe the intestine lining, they are:

1. Rose Petal

Rose petals have anti-inflammatory, anti-parasitic and antiseptic properties. Rose petals can be consumed daily on an empty stomach or you can soak rose petals in water overnight and have water on an empty stomach in the morning helps in soothing the intestine lining.

2. Carrot Soup

Carrots are rich in Vitamin K, potassium, fibers that help to manage indigestion. Making carrot soup and having twice daily will help to heal inflammation, heartburn, abdominal pain, etc.

3. Yogurt

Yogurt contains lots of natural probiotics that help in boosting the functions of the digestive tract. Consuming a bowl of yogurt with breakfast will help to heal various ulcerative colitis symptoms like indigestion, abdominal pain, etc.

4. Coconut Water

Coconut water has cooling effects and helps to maintain the digestive fire. Drinking 1-2 glass of coconut water twice daily will help in reducing inflammation.

5. Bananas

Bananas are very helpful for ulcerative colitis patients. It contains pectin which helps in digestion problems. Bananas also contain active compound Rutin and antioxidants which help in reducing inflammation. Have 1-2 bananas in a day is helpful in this condition.

Foods Which you Have to Avoid

  • Caffeine
  • Alcohol
  • Carbonated drinks
  • Dairy products
  • Potatoes
  • Fatty meat
  • Vegetables like; cabbage, broccoli, etc.
  • Spicy foods
  • Nuts and seeds

Some Dietary Guidelines Are

  • Keeping yourself hydrated, having plenty of fluids
  • Organize small and more regular meals
  • Keeping a low fiber diet, if you have loose stools
  • Keeping a low salt diet
  • Keeping a low-fat diet

Conclusion

From the above information, Ulcerative colitis is an inflammation of intestinal lining which further ends up with erosions called ulcers and develops various symptoms like diarrhea, abdominal pain, bleeding per rectum, etc. But which can be easily manageable by some home, herbal remedies and by keeping track of the food