Author: Dr. Vikram Chauhan

Ayurvedic View on Latent Autoimmune Diabetes in Adults (LADA)

Abstract

Diabetes is the most widely recognized disease on the planet and a significant danger to worldwide well-being. As it is a persistent infection, essential and optional counteraction is vital to diminish its weight on individuals and society. Individuals with LADA might have symptoms of diabetes type 2, however, their bodies produce antibodies that disrupt the body’s capacity to control glucose. Individuals with LADA might utilize insulin or different drugs to control glucose and slow pancreatic harm. In this article, we will examine causes, Symptoms, risk factors, diagnosis, complications, Ayurvedic overview, and treatment.

Introduction

LADA is a type of diabetes that usually affects older people after the age of 35. Individuals with LADA may experience symptoms of both type 1 and type 2 diabetes. In LADA, people develop antibodies that affect the pancreas’s ability to control blood sugar. Individuals with LADA may not initially be insulin resistant, meaning their pancreas can still produce insulin. Doctors may diagnose these people with diabetes 2 type, but people with diabetes 2 type do not develop the antibodies that cause LADA. Unlike diabetes 1 type mellitus, LADA progresses slowly, which explains why it is not diagnosed until later in life. LADA accounts for 2-12% of all diabetes.

Diabetes 1 Type

On the point, the pancreas produces little or no insulin, known as diabetes type 1. It is a chronic disease. It mostly appears in adolescence.

Diabetes 2 Type

When the body does not use insulin properly, known as diabetes type 2. It manages lifestyle changes and physical activities.

Causes of Lada

It happens when your pancreas is harmed by antibodies and doesn’t create sufficient insulin, which gradually obliterates the insulin-delivering cells in your pancreas. Hereditary elements may likewise be involved. In LADA, during which the pancreas is harmed, the body annihilates the beta cells of the pancreas, like sort 1 type.

Symptoms of Lada

LADA symptoms, such as:

  • Polydipsia
  • Polyuria
  • Skin infection
  • Weight gain
  • Blindness or blurred vision
  • Dry skin
  • Fatigue
  • Nausea
  • Vomiting
  • Bladder infection
  • cuts and bruises that heal slowly

Complications of Lada

Similar to type 2 diabetes, LADA patients may be at risk for microvascular complications, including

  • Renal damage
  • Disorders of the eye such as vision
  • Nerve damage causes pain, tingling, and loss of sensation in the hands and feet.
  • DKA (Diabetic Ketoacidosis)- Diabetic ketoacidosis occurs when cells cannot get the glucose they need and the body switches to burning fat for energy. This creates ketones that are responsible for the fruity odour of the breath. DKA leads to Diabetic coma. Symptoms are as follows: High blood sugar, unintentional weight loss, weakness, vomiting and changes in mental state.

Risk Factors

There are some risk factors for developing LADA include

  • Excessive weight or obesity
  • Low birth weight
  • Low physical activity
  • Psychosocial stress

Diagnosis of Lada

  • GADA antibody test – this test is mainly used for latent autoimmune diabetes. It is a touchy marker of this disease as it is a predominant autoantibody.
  • C-peptide – to find out the level of insulin produced by the body
  • FPG test- Assuming the glucose level is in excess of 126 mg/dl shows diabetes.
  • RPG test-  Assuming the glucose level is in excess of 200 mg/dl or higher it indicates diabetes
  • Urinary sugar test- Usually, when blood sugar rises above 180 mg/dl, sugar is released in the urine. However, in the case of renal glycosuria, the kidneys start to work less and even if the blood sugar is below 180 mg/100 ml, glucose can be excreted in the urine
  • GTT- A night fast for 12 hours or less is required. Glucose (75 g for adults and 1.75 g/kg body weight for children) was given orally after a rapid blood test. After two hours, samples of blood were taken and blood glucose levels were measured. Whenever diabetes is analysed, the test does not need to be repeated.

Ayurvedic Overview of Lada

जात: प्रमेही ————- विकारा भवन्ति तांश्च प्रवदन्त्य साध्यान।। (Ch. chi. ६/५७)

As mentioned above- LADA is related to sahaja prameha and is created by innate factors. People born with Prameha disease or inherited from a father with diabetes have no cure due to genetics. Any family disease is considered incurable. Prameha includes all doshas. Kapha causes premeha by influencing medas (lipid digestion) in the bladder, muscles and body liquids. Pitta, who is uncomfortable with hot things, will do the same by influencing the places mentioned. Vayu causes prameha by consuming dhatus in the bladder with a diminished portion compared with the other two. Dosha produces different sorts of prameha by arriving at the bladder and influencing the urine.

Nidana of Lada (Causes)

आस्यासुखं स्वप्नसुखं दधीनि ग्राम्योैदकानूपरसाः पयांसि।

नवान्नपानं गुडवैकृत च प्रमेहहेतुः कफकृच्च सर्वं।। (Ch. Chi.  ६/४)

According To Acharya Charaka

  • Sleeping too much
  • Inactivity
  • Eating too much curd
  • Eating too much swamp meat.
  • Eating too many aquatic animals.
  • Overeating.
  • Jaggery
  • New Grains
  • Foods that increase Kapha dosha too much

Samprapti Chakra (Pathophysiology) of Latent Autoimmune Diabetes

दोषो हि बस्तिं समुपेत्य मूत्रं संदूष्य मेहाञ्जनयेद यथास्वम।। (Ch. Chi. ६/६)

According to Acharya Charak, one of the energies in Vata, Pitta or Kapha condenses and reaches the bladder and contaminates the urine, causing symptoms.

Dosha and Dusya Involved in It

  • Doshas: Vata, Pitta and Kapha
  • Dusyas: Marrow, Meda, muscle fat, Rakta, Shukra (semen), fluid, lymph, and so forth

Prameha’s Types

There are clinically two types

  • Sthula Parmeha- Urinary tract infections in obese individuals.
  • Krisha Parmeha- Urinary tract infections in thin individuals.

Symptoms of Prameha

Acoording to Acharay Sushruta

तत्राविलप्रभूतमूत्रलक्षणा: सर्व एव प्रमेहा: (Su. Ni. ६/६)

Turbidity and excessive urination is the symptom of all prameha roga.

Management of Parmeha Roga

  • In Obese patients (Sthula Parmeha)- Sanshodhan chikitsa (purification) should be followed by Brihana chikitsa (nourishing).
  • In Thin patients, (Krisha Parmeha)- Brihana (nourishment) chikitsa should be given.
  • Snehan chikitsa (Oleation)- Oils such as Mustard oil (Sarsapa), etc.
  • Swedan (Fomentation) is strictly contraindicated in Parmeha.

Herbal Remedies for Latent Autoimmune Diabetes by Planet Ayurveda

Planet Ayurveda is a GMP-certified Ayurvedic clinic that manufactures a variety of medicines to treat various health issues and provide relief to patients. All formulations of Planet Ayurveda contain no preservatives, additives or resins. Planet Ayurveda offers many herbal remedies targeting diseases with no side effects.

  1. Dia-Beta Plus
  2. Karela Capsules
  3. Madhumehantak Churna
  4. Fenugreek Capsules

Herbal Remedies for Diabetes

Buy Now: Herbal Remedies for Diabetes

Product Description

1. Dia-Beta Plus

These are polyherbal capsules. It contains various herbs such as Gurmaar (Gymnema sylvestre), Tulsi (Ocimum tenuiflorum), Vizaysaar (Pterocarpus marsupium) etc. Gurmaar is also known as the destroyer of sugar or anti-diabetic. It has been used in combination with other diabetes medicine. Karela has anti-diabetic action, its extract is used as a vegetable insulin. Saptrangi is traditionally used to cure ailments such as obesity and diabetes. These capsules detoxify the body. It purifies the blood and has analgesic, anti-inflammatory and analgesic properties.

Dosage: 2 capsules two times a day.

2. Karela Capsules

It consists of one herb that is Karela (Momordica charantia). It is bitter in taste. Karela is very helpful in reducing blood sugar and cholesterol levels. It balances all three principles in your body. It includes charantin which brings down the blood glucose level in the body and helps in maintaining diabetes. Karela also helps in blood purification.

Dosage: 2 capsules after meal.

3. Madhumehantak Churna

This polyherbal churna contains Saptrangi (Salacia chinesis), Vijaysar (Pterocarpus marsupium), Bilva patra (Aegle marmelos), Gurmaar (Gymnema Sylvestre), Neem patra (Azadirachta indica), Karela (Momordica charantia), Tulsi (Ocimum sanctum), Jamun (Syzygium cumini) etc. Neem has carminative, antibacterial and anti-diabetic action. This jamun can control the frequency of urination and help lower sugar in the urine and blood. Using tulsi facilitates kapha and vata, but makes pitta heavier. It helps to clean the blood.

Dosage: 1 tsp twice daily before meal.

4. Fenugreek Capsules

These capsules contain only one herb- Fenugreek (Trigonella foenum graecum). The taste is bitter, the effect is mild, sharp and subtle. It quiets Vata and Kapha but Pitta is aggravated. It increases appetite, improves digestion, is a gentle purgative and has anti-inflammatory properties. Advances lactation and controls post-pregnancy pain. It is hostile to diabetic properties. As well as supporting weight reduction, the cycle likewise lessens serum lipids.

Dosage: 1-2 capsules two times a day.

Conclusion

Latent autoimmune diabetes is an autoimmune disease in adults with features of type 1 and type 2 diabetes. So this is also called type 1.5 diabetes mellitus and you need insulin for at least the first month after diagnosis to control your blood sugar. This is a type of congenital diabetes. In Ayurveda, it is associated with Sehaj Parmeh (hereditary diabetes). It is difficult to treat, but there are some herbs in the Ayurvedic world that can help treat autoimmune diabetes without causing side effects.

Testicular Atrophy Symptoms, Causes and Treatment with Ayurveda

Abstract

Atrophy is a medical terminology used for reduction/decrease in size or wasting away of any tissue or organ of the human body. Also to denote paused development or incidental organ loss. It can be a result of physical inactivity, malnutrition, genetics and old age. Atrophy can be seen in patients with chronic disorders like paralysis or any disease in which a patient is bedridden for a long duration. They feel difficulty in moving and pain. Atrophy is classified under motor neuron disease. Testicular Atrophy is particularly related only to male gonads.

Testicular Atrophy

Introduction

It is a medical condition in which the male reproductive glands Testicles shrink in size and functioning also get affected. They produce less amount of sperm. This condition can be seen in both the testes. This condition is seen as the result of loss of leydig and germ cells present inside testicles. These germ cells produce sperm cells. This condition can be treated in early stages. If kept untreated or ignored can become more chronic and irreversible .

Signs and Symptoms

  • Shrunken testis, smaller than normal size
  • Infertility or temporary impotence
  • Erection problems/erectile dysfunction
  • Decreased libido and stamina
  • Testes have soft consistency
  • Beard and pubic hair growth is not enough
  • A feeling of heaviness in the scrotum
  • Mild ache in lower abdomen

Causes

Few common causes are-

  • Age
  • Hormonal imbalance
  • Alcoholism
  • Varicocele
  • Orchitis (inflammatory disease of testes)
  • Disease condition can also result in atrophy
  • Testicular torsion
  • Cryptorchidism (undescended testes)

Diagnosis

  • Size
  • Shape
  • Texture
  • Firmness
  • And also muscle built, texture, and beard growth are examined

To diagnose testicular atrophy following examinations are done-

Lab Investigations

  • Serum testosterone level
  • Free testosterone level – these laboratory tests are important as they give an idea about the functioning of testes.
  • Low level of serum testosterone and normal value of testosterone shows unilateral testicular atrophy.

Genital Examinations

  1. While patient is Standing
  2. Patient in Lying down position to check – size, presence of varicocele, consistency and presence of pubic hairs.

Complete History

For proper diagnosis and cure an exact history with systematic order is required. Such as past history of any illnesses, family history, previous operations, medication history, UTI or STD, these points help in diagnosing.

Scrotal Hypolasia

Incomplete development of scrotum . not completely descended.

Ultrasonography of Testes

It plays an important role in examination of testes. If any varicocele or lump/sac is present or any growth is seen.

Treatment

  • Antibiotics
  • Painkillers
  • NSAIDs
  • Hormonal balancing
  • Lifestyle changes
  • Surgical removal
  • Symptomatic treatment for varicocele , torsion and undescended testes.

Ayurvedic Aspect and Treatment 

Testicular Atrophy is described as the vrishna shosha, caused due to imbalance of vata dosha and mamsa dhatu.Due to improper ahara-vihara and muscle wasting VATA dosha get aggravated in the body. INCREASED VATA dosha Causes decrease or Kshaya of Dhatus (especially Mamsa dhatu Kshya and nerve weakening) also called VRISHANA SHOSHA (Testicular atrophy)

 Causes of Shosha

  1. Adhwagamana janya shosha – excessive walking
  2. Vyayam janya shosha – excessive physical exercise
  3. Vardhakya janya shosha – ageing , old age effect
  4. Vrana Janya shosha – ulcers
  5. Shoka janya shosha – excessive grief
  6. Urahkshata janya shosha – chest injury
  7. Vyavaya janya shosha – excessive exhaustion

Remedies 

  1. Exercising
  2. Vitamin E intake
  3. Herbs like Ashwagandha, gokshura, giloy, and many others .

Herbal Remedies for Testicular Atrophy by Planet Ayurveda

Planet Ayurveda manufactures Ayurvedic medicines derived entirely from plants. Planet’s medicine does  not contain additives, chemicals or preservatives. All products are GMP certified and 100% vegan. Planet Ayurveda provides herbal remedies for Testicular Atrophy they are as following:

  1. Atirasadi Churna
  2. Chandraprabha Vati
  3. Tribulus Powder
  4. Male Support Formula
  5. Musli Strength

 

Herbal Remedies for Somatoform disorders

Product Description

Atirasadi Churna

Atirasadi churna is an amazing formulation for muscles and helps in testicular Atrophy by enhancing muscle tone, firmness and texture also by increasing testosterone levels and prepared by the combination of various herbs like Gokshura (tribulus terrestris), Safed musli (chlorophytum borivilianum), Ashwagandha (withania somnifera), Kali musli (curculigo orchioides),  Shatavari (Asparagus racemosus) etc.

Dosage- 1 tsp twice daily with a glass of warm water.

Chandraprabha Vati

This is a classical preparation which helps in erectile dysfunction, good muscle growth and boosting testosterone this a tablet form, formulated by using various herbs like shilajit(Asphaltum), guggul(commiphora mukul), sharkara(sugar), karpoor(cinnamomum camphora), vacha (Acorus calamus), guduchi(Tinospora cordifolia).

Dosage- 1 tablet twice daily after meals

Tribulus Powder

This is a capsule formulation of gokshura (devil’s thorn) which is considered as a great stamina and power booster, as it helps in increasing muscle tone and boosts testosterone levels in male.It is useful in testicular atrophy as it brings testosterone and testosterone serum levels normal. It is prepared by using standardized extract of Gokshur (tribulus terrestris).

Dosage– 2 capsules with water after food daily

Male Support Formula

This is a tablet formulation by planet ayurveda, which acts as a testosterone booster and enhances reproductive health by preventing any muscle or functioning weakness. This is made with potent herbs such as Ashwagandha(withania somnifera) shilajit(black bitumen) gokshura(tribulus terrestris).

Dosage – 2 Capsules daily with water after food.

Musli Strength

Musli strength is a planet ayurveda’s formulation And it has the capacity to pacify vata dosha, maintain hormonal disbalance and make muscle and skin texture strong. High testosterone levels help in hair growth and strong skin texture. Which helps in maintenance of testicular atrophy. This formulation is manufactured using herbs like safed musli (Chlorophytum borivilianum) and gokshura (Tribulus terrestris).

Dosage- 1 capsule twice daily with 1 glass of normal water after meals.

Conclusion

Testes are important reproductive organs in males which have various functions in human males such as reproduction, proper development of male characters and many chemical and body functions. This article covers a complete knowledge about testicular atrophy and its ayurvedic relation, dosa vitiation, and causes, symptoms, treatment and important herbs, and formulations. With our faith, trust and belief over Indian medical science now we are able to manage those disorders which were considered incurable. Follow a healthy lifestyle and stay healthy.