Author: Dr. Vikram Chauhan

What is Fasting Insulin and its significance for Diabetic patients?

Abstract

Diabetes mellitus is a non communicable disease but is spreading like a pandemic all over the world. Each and every house is having at least two members who are diagnosed with diabetes. The commonest type of diabetes is diabetes mellitus type 2 but the patients of diabetes type 1 are also increasing day by day. Diabetes mellitus is a clinical syndrome that is characterized by hyperglycemia due to absolute or relative deficiency of insulin. In this article we will mainly discuss the significance of fasting insulin with respect to insulin dependent Diabetes Mellitus or diabetes type 1 and also non insulin dependent diabetes or diabetes type 2.

Introduction

Diabetes is worldwide in distribution and the incidence of both types of primary diabetes, i.e insulin dependent diabetes mellitus (IDDM) or diabetes mellitus type 1 and non insulin dependent diabetes (NIDDM) or also known as diabetes mellitus type 2. However prevalence of both varieties varies considerably in both parts of the world. This Seems to be due to differences in both genetic and environmental factors. To Begin with almost certainly the term diabetes mellitus embraces a heterogenous group of disorders having differing modes of inheritance. Agreement appears to be near at hand that IDDM and NIDDM exhibit substantial genetic differences.

Diabetes mellitus

Stages of Diabetes

1. Overt or manifest diabetes

It refers to the fully expressed clinical syndrome. This stage of disease is characterized by fasting hyperglycemia, glucosuria and usually three p’s that are polyuria, polydipsia and polyphagia.

2. Subclinical diabetes

Subclinical diabetes is understood when the patient is completely asymptomatic and fasting blood glucose level is usually normal but the post prandial level (glucose levels after two hours of meal) is frequently elevated.

3. Latent or stress diabetes

These patients are at the risk of developing overt diabetes. It basically refers to a person who is completely asymptomatic and under ordinary condition is normoglycemic and has a normal glucose tolerance. But under stress like pregnancy, infection and other serious conditions temporary carbohydrate intolerance develops.

4. Prediabetes or potential diabetes

This is a conceptual state which can be applied only retrospectively to the period of time preceding carbohydrate intolerance.

Pancreatic pathology for insulin dependent diabetes mellitus

Three outstanding features characterise the pathological picture of prediabetic pancreas in IDDM

  1. ‘Insulitis’ which  is the infiltration of the islets with mononuclear cells.
  2. The initial patchiness of this lesion with, until a very late stage, lobules containing heavily infiltrated islets commonly seen immediately adjacent to unaffected lobules.
  3. The striking beta cell specificity of the destructive process within infiltrated islets where the glucagon and other hormone secreting cells invariably remain intact.

Things about insulin

Insulin is a peptide hormone secreted by beta cells in pancreatic islets of langerhans and its main function is to lower the serum glucose levels and hence promote anabolism. It is a normal growth factor required for development.  Glucose production and secretion by the liver is strongly inhibited by high concentration of insulin in the blood. Decrease or absence of insulin activity results in diabetes mellitus of either type 1 or type 2. Human insulin protein is composed of 51 amino acids and has a heterodimer of an A- chain and a B-chain which are linked together by disulfide bonds.

Fasting insulin

What is fasting insulin?

Fasting insulin is the name given to a diagnostic test which is used to measure the amount of insulin in blood. As mentioned before insulin is very much important for utilization of blood glucose and hence maintaining rights levels of it. In absence of insulin a condition called hyperglycemia usually occurs. So determining correct levels of insulin in blood is necessary so as to evaluate what exactly is the condition.

Insulin test preparation

Fasting insulin requires at least 8 hours of fasting. This means that before giving a blood sample, a patient should have not eaten anything for around 8 or more than 8 hours.

Purpose of fasting insulin

  1. To find reasons for hypoglycemia
  2. Diagnosing insulin resistance
  3. To find out tumors on the pancreases.
  4. This tumor is called insulinoma.

Test results showing insulin resistance or no insulin resistance

  1. If your body cells have developed insulin resistance then fasting insulin is more than 48pmol/L.  
  2. If your body cells are not having any kind of insulin resistance then fasting insulin is 18-48 pmol/L.

Importance of fasting insulin with respect to hyperglycemia or both form of diabetes

Insulin as mentioned earlier is very important as it is responsible for glucose take up by the cells. Our body cells like cells of muscle tissue, cells of various organs use glucose as a source of energy. They are having specific insulin receptors. Insulin is attached to these receptors and hence the glucose is binded to it. Then this glucose is taken up by the cells which then convert it into energy or store it for later use as a source of energy. But if these receptors do not determine insulin than glucose uptake by the cells does not take place or in other scenarios due to pancreatic cell destruction as a result of the autoimmune process there is absolute deficiency of insulin resulting in hyperglycemia.

So, advising fasting insulin is of great importance in both above mentioned cases. Reason is, this test help in determining:

  1. The exact levels of insulin in body
  2. Determining the type of diabetes especially in case of children
  3. Deciding the type of diet which can be followed
  4. Determining the units of insulin which are to be administered.

Conclusion

Diabetes is no doubt setting its roots deep and deeper into our society. Though we have many effective ways to deal with this group of conditions but still it becomes challenging with each and every patient diagnosed. It is very important to understand that this condition is related to both genetic and environmental factors along with some personal habits. Moreover insulin, whose deficiency is the main reason for hyperglycemia cannot be generated through medicines but its requirement is fulfilled by administration of synthetic insulin.

Ayurvedic Treatment of Systemic Gonococcal infection

Abstract

Gonorrhea can be defined as a sexually transmitted infection induced by the bacteria named as “Neisseria gonorrhoeae”. With the passage of time, infection can spread to the whole bloodstream and various body parts. This infection can mainly affect one or more of the following body parts at initial stages

  1. Cervix
  2. Rectum
  3. Throat
  4. Urethra

The infection causing bacteria can also get entry into newborns during birth if their mother is suffering from untreated infection. The main body part affected in the babies due to untreated gonorrhea infection is their eyes.

If the treatment of infection is not taken at the right time, Gonorrhea infection may lead to a serious medical condition, Systemic gonococcal infection which is also known as disseminated gonococcal infection.

Symptoms of Gonococcal Infection

Symptoms of Gonococcal Infection and Systemic Gonococcal Infection

  1. Pain during urination or burning sensation during urination
  2. Increased vaginal discharge
  3. Thick discharge from the penis
  4. Spotting between menstrual periods
  5. Swollen or painful testicles
  6. Painful movements of bowel
  7. Sore throat
  8. Anal discharge
  9. Anal itching

If the proper treatment of Gonorrhea infections is not taken at the correct time, the bacteria may spread into other body parts also and make the symptoms more severe. Specific symptoms depend upon the affected body area.

Symptoms observed in the patients of systemic gonococcal infection are

  1. Swelling in the joints
  2. Fever or chills
  3. A skin rash with red or pink spots filled with pus
  4. Pain in the tendons of the heels or wrists
  5. Pain in the joints
  6. Feeling ill or generally unwell

Causes

Gonorrhea is a sexually transmitted disease which means it can spread through anal, vaginal or oral sexual intercourse if not done safely, means without using any protection. Systemic gonococcal infection can develop within 2 weeks of contracting gonorrhea. Once the infection begins to develop in the blood, it can affect various body tissues and can damage them permanently.

Risk Factors

Gonorrhea is a very common sexually transmitted infection, but several people are at increased risk of developing gonorrhea, such as

  1. People doing sexual intercourse without using any protection
  2. People aged less than 25 years
  3. People having more than one sex partner

Diagnosis

When you visit a doctor’s clinic, the doctor will observe your symptoms to check whether you have gonorrhea or any symptoms of systemic gonococcal infections. The doctor may also take a sample or culture from the affected area and send it to the laboratory for analysis. The doctor may take the culture for testing from

  1. The blood
  2. A skin lesion
  3. The anus
  4. The throat
  5. The cervix
  6. Fluid from the joints
  7. The urethra

If the test results for gonorrhea are positive, then the doctor may prescribe some other tests also to determine if the patient has other STIs. Gonorrhea is often diagnosed alongside other STIs, for example chlamydia.

Treatment

The treatment of Systemic Gonococcal infection is very easy with Ayurvedic medicines. Ayurveda system of medicines is a traditional 5000 years old medicinal system originated from India. All Ayurvedic medicines are prepared from herbs present in nature. These medicines treat the disease in a natural manner and prevent its recurrence without showing any side-effects in the body of the patient.

By following the basic principles given in Ayurvedic literature, PLANET AYURVEDA prepared some wonderful effective remedies to treat the patients suffering from Gonorrhea as well as Systemic gonococcal infection. All the remedies of Planet Ayurveda formulates under the strict supervision of expert M.D. Ayurveda doctors who ensure the product is completely natural and independent from any kind of chemical substance, preservative, filler, flavor, binder, color or any artificial material. Thus, these products are 100 percent natural and don’t possess any side-effects in the patient. Take a look at these marvelous herbal remedies.

Treatment of Systemic Gonococcal infection

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Herbal Remedies by Planet Ayurveda

  1. Neem Capsules
  2. Gandhak Rasayan
  3. Kaishore Guggul
  4. Chandanadi Vati
  5. Mutrakrichantak Churna
  6. Punarnava Capsules

Product Description

1. Neem Capsules

Neem capsules by Planet Ayurveda are made up of standardized extract of Neem (Azadirachta indica) which is a well-known herb due to its multiple health beneficial properties. These capsules will help you in treating systemic gonococcal infection, heart disorders, wounds, skin infections, anxiety, as well as in pacifying digestive fire, and improving overall body health.

Dosage: 2 capsules twice daily with normal water after meals.

2. Gandhak Rasayan

Planet Ayurveda has been prepared Gandhak Rasayan tablets by using high quality extract of Shuddh Gandhak (Purified sulphur) which is very advantageous in treating multiple health disorders such as systemic gonococcal infection, disorders of female reproductive system, skin, etc.

Dosage: 2 tablets twice daily with lukewarm water after meals.

3. Kaishore Guggul

Vidanga (Embelia ribes), Ginger (Zingiber officinale), Amalaki (Emblica officinalis), Haritaki (Terminalia chebula) and seven more herbs are extracted and used in processing Kaishore Guggul tablets. Consuming these tablets will enhance the health of whole body organs such as skin, pancreas, etc. Patients will get relief from systemic gonococcal infection up to a great extent after taking these tablets.

Dosage: 2 tablets two times daily with lukewarm water.

4. Chandanadi Vati

Chandanadi vati tablets prepared in the house of Planet Ayurveda consist of best quality extracts of Amalaki (Emblica officinalis), Gokshura (Tribulus terrestris), Rasaut (Berberis aristata), Kapur (Cinnamomum camphora), etc. All these herbs work in a synergistic manner to treat various body diseases such as Systemic Gonococcal infection, constipation, fever, etc. Along with that, these tablets also maintain the balance between Kapha and Pitta Doshas, regulating the health of the digestive system, body metabolism, and circulation of the blood.

Dosage: 2 tablets two times daily with lukewarm water.

5. Mutrakrichantak Churna

It is a blend of four effective herbs such as Varun (Crataeva nurvala), Gokshur (Tribulus terrestris), Bhumi Amla (Phyllanthus niruri), Kalmegh (Andrographis paniculata). This churna is useful in supporting a healthy urinary system, kidneys, and enhancing overall body health.

Dosage: Take 1 teaspoon daily twice daily with water after meals. Boil 1 tsp churna in 400 ml water and boil until the water remains 50 ml. Filter the strain and drink. Prepare a fresh decoction everytime.

6. Punarnava Capsules

Standardized extract of Punarnava (Boerhavia diffusa) is consumed in manufacturing Punarnava capsules. Benefits of these capsules include: management of Kapha Dosha (cold, cough), Pitta Dosha (digestive fire), treatment of blood disorders, skin disorders and strengthening the immune system of the body.

Dosage: 2 capsules two times a day with normal water, after meals.

Contact Planet Ayurveda to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214030 Or Check Website – www.PlanetAyurveda.com

Conclusion

After reading this article, we get to know about the various aspects of systemic gonococcal infection. Treatment of this disease at the right time is very mandatory as it can interfere with daily routine activities. Above mentioned herbal remedies are very effective in treating systemic gonococcal infection in a natural manner without showing any side effects. Any person of any age can consume these medicines to get rid of systemic gonococcal infection.