Severe combined immunodeficiency is a rare genetic illness that occurs due to genetic abnormalities that disrupt the functional development of B cells and T cells and modify the clinical presentation. Other names for it include Swiss-type agammaglobulinemia, bubble boy disease, and bubble baby disease. There are roughly 13 different genetic disorders that can cause severe combined immunodeficiency. These flaws also make people highly susceptible to life-threatening diseases. Infants with 80% severe combined immunodeficiency do not have a family history of the condition. In this article, we will read briefly about severe combined immunodeficiency.
Severe combined immunodeficiency is an uncommon disorder caused by genetic abnormalities that affect immune cell function and development. Infants with severe combined immunodeficiency appear healthy but are incredibly vulnerable to life-threatening infections. Until or unless newborns undergo immune restoration therapy, such as gene therapy, enzyme therapy, and hematopoietic stem cells.
- Common gamma chain of the T-cell receptor deficiency
- Recombinase activating genes 1 and 2 deficiency
- Adenosine deaminase deficiency
- Janus kinase 3 deficiency
- Alpha-chain deficiency of the IL-7 receptor
- CD3 chain deficiency
- Gene mutation
- Artemis deficiency
- Oral thrush
- Delayed growth
- Recurrent infections
- Difficulty in weight gain
- Respiratory infections
- Failure to thrive
- Sinus infections
- Ear infections
- Blood infection
- Complete medical history
- Physical examination
- TREC test (T-cell receptor excision circle)
- WBC count
- DNA tests for genetic mutations.
- Bone marrow transplant
- Gene therapy
- Supportive care
- Hematopoietic stem cell transplantation
- Prevent baby from infection or a cold
- Avoiding public places
- Wash your hands properly before touching the infant.
- Limiting visitors
AYURVEDIC ASPECT OF SEVERE COMBINED IMMUNODEFICIENCY
In Ayurveda, we can correlate severe combined immunodeficiency with anuvanshik vyadhi (inherited disease) and oja kshaya (immune deficiency). Anuvanshik vyadhi in a person develops at birth as a result of beej dosha (sperm and ovum malformation). Oja refers to immunity or resistance to diseases of two types: one that lessens the manifestation of the disease, and the other variety that prevents the manifestation of diseases. Normal doshas (vata, pitta, and kapha), equilibrium state of dhatu, normal agni, patency of srotas, and other factors that support the equilibrium condition of all physiological parameters are the factors that lead to oja (immunity). Oja is the core of rasadhi dhatus, which is also known as bala (strength).
CAUSATIVE FACTOR OF OJA KASHAY
अभिघातात् क्षयात् कोपाच्छोकाद्धयानाच्छ्रमात् क्षुधः।
ओजः सड्.क्षीयते ह्योभ्यो धातुग्रहणनिः सृतम्।
तेजः समीरितं तस्माद्विस्त्रंसयति देहिनः।। (सु.सू १५ /२८)
According to Acharya Sushruta, Ojas decreases as a result of any injury or harm.
- Body discomfort
- Tissue exhaustion
- Hunger, etc., causes fluid to flow out of the dhatus and become associated with tejas under the control of vata.
CLINICAL FEATURES OF OJA KASHAY
मूर्च्छा मांसक्षयो मोह: प्रलापोऽज्ञानमेव च ।
पूर्वोक्तानि च लिङ्गानि मरणं च बलक्षये ।। (सु.सू १५ /३२)
- Wasting of muscles
- Improper perception of knowledge
Oja kshaya and anuvanshik vyadhi are incurable because of improper understanding. We can only provide supportive care using herbal medications to stop the disease from getting worse and provide some immunity to fight against other infections.
HERBAL REMEDIES FOR SEVERE COMBINED IMMUNODEFICIENCY BY PLANET AYURVEDA
Planet Ayurveda is a certified Ayurvedic clinic, and the formulation of different types of remedies is performed here to provide relief from diseases. All formulations at Planet Ayurveda are made organically without the use of preservatives. All of the plants used to make medicine are pure, natural, and extremely effective. Planet Ayurveda offers a variety of herbal products that have no side effects for supporting the treatment of severe combined immunodeficiency.
- TELOMERE BOOSTUP
- IMMUNE BOOSTER
- AMALAKI RASAYAN
- ASHWAGANDHA CAPSULE
- SHILAJIT CAPSULES
- GANDHAK RASAYAN
1. TELOMERE BOOSTUP
Telomere boostup are multi-herbal capsules that are formulated by Planet Ayurveda with the help of Vitis vinifera (Grapeseed), Withania somnifera (Ashwagandha), Amla (Emblica officinalis), and some other ingredients. Ashwagandha prevents all types of weakness, enhances strength and stamina, and improves general alertness. It contains analgesic, aphrodisiac, anti-inflammatory, and diuretic properties. It helps with digestion. It first targets the ama dosha and prevents its buildup. It primarily functions as a rasayana, vajikarana, and ojovardhak, and it also inhibits the production of arbuda and granthi.
Dosage: with plain water, take one capsule twice daily, after meals.
2. IMMUNE BOOSTER
Immune booster is a multi-herbal formulation that is formulated by Planet Ayurveda with the help of Vitis vinifera (Grape seed), Bovine colostrum (Go-Piyushs), Emblica officinalis (Amalaki), and Phyllanthus niruri (Bhumi amla). Bhumi amla is beneficial for liver disease because it normalizes the bilirubin level. It is also beneficial for bacterial and viral infections. It also helps with skin conditions and kidney-related diseases. It consistently strengthens and maintains a healthy immune system.
Dosage: with plain water, take 2 capsules twice daily, after meals.
3. AMALAKI RASAYAN
Amalaki rasayan is a single herbal capsule formulated by Planet Ayurveda with the help of Amalaki (Emblica officinalis). Amla is a rich source of vitamin C, which is helpful in eye diseases. It provides strength to the muscles of the eyes and nourishment to the eyes. Amalaki has a cooling and soothing effect. It helps in pacifying tridoshas and working more on pitta dosha. It has analgesic and anti-inflammatory properties and is also a rich source of natural antioxidants.
Dosage: with plain water, take one capsule twice daily, after meals.
4. ASHWAGANDHA CAPSULE
Ashwagandha capsules are multi-herbal capsules that are formulated by Planet Ayurveda with the help of Withania somnifera (Ashwagandha). Ashwagandha has significant immune-boosting properties. It has been demonstrated to support immune cells that fight infection and reduce inflammation. Ashwagandha is extremely helpful in painful situations like arthritis because it has strong anti-inflammatory qualities.
Dosage: with plain water, take two capsules twice daily, after meals.
5. SHILAJIT CAPSULES
Shilajit capsules are single herbal capsules that are formulated by Planet Ayurveda with the help of Shilajit (Asphaltum). Shilajit is the result of a protracted process of mineral and plant matter degradation. It is a tar-like, sticky substance that comes from rocks and is only present in high mountain areas. Shilajit has been used for a long time to prolong life and slow ageing. The ingredients may help control cognitive problems. It is also beneficial for aging, anemia, antivirals, chronic fatigue, liver cancer, heart health, obesity, and male fertility.
Dosage: with milk or plain water, take 1 capsule twice daily, after meals.
6. GANDHAK RASAYAN
Gandhak rasayan is a single herbal tablet formulated by Planet Ayurveda with the help of shuddha gandhak (Purified sulphur). It is an immunity booster. It acts as an antibacterial, antimicrobial, and anti-inflammatory herb. It pacifies all three doshas, which are vata, pitta, and kapha. It also purifies the blood. It is useful for urinary tract infections and removes harmful pathogens from the body. It increases body strength and boosts immunity.
Dosage: with lukewarm water, 2 tablets twice daily, after meals.
Contact Planet Ayurveda Support Team to provide you the costing/ordering and delivery information at – firstname.lastname@example.org or Call at 0172-521-4040 (India), +91-172-521-4040 (Outside India) or Whatsapp at (+91) 842-749-4030.
Severe combined immunodeficiency is a rare genetic illness that occurs due to genetic abnormalities that disrupt the functional development of B cells and T cells and modify the clinical presentation. Infants with severe combined immunodeficiency appear healthy but are incredibly vulnerable to life-threatening infections. In Ayurveda, we can correlate severe combined immunodeficiency with anuvanshik vyadhi (inherited disease) and oja kshaya (immune deficiency). Anuvanshik vyadhi in a person develops at birth as a result of beej dosha (sperm and ovum malformation). In Planet Ayurveda, there are some herbal remedies that are beneficial for the Treatment of Severe combined immunodeficiency without causing any side effects.