Category: Ankylosing Spondylitis

Osteogenesis Imperfecta/Brittle Bone Disease Treatment in Ayurveda

ABSTRACT

Osteogenesis imperfecta (OI) also called the brittle bone disease is a genetic bone disorder inherited from parents to the new born babies and are born with this disorder and due to this the bone breaks easily better to say that their bones are fragile which fractures even with a very mild trauma, possibly by crawling or walking too. As the name “Osteogenesis imperfecta” itself says – imperfect formation of the bone. This condition is considered to be an irreversible life long condition. It is a rare condition found in babies but once born with this condition they have to deal with it forever. This disease is also classified to further four types according to the degrees of severity. The management of this particular condition just needs to prevent fracture and deformity of the bone. Ayurveda also considers this condition to be Sahaja Vyadhi (genetic disorder) and provides a number of combinations of herbal drugs for the management and improvement of the condition.

INTRODUCTION

Osteogenesis imperfecta (OI) or brittle bone disease is a rare disorder of the bone in which the babies are born with lower bone density that makes their bone fragile and ultimately prone to fractures. This genetic disorder is caused due to abnormally formed bones. The signs and symptoms vary according to the severity of the disease. This condition can also be determined before birth during intrauterine life by a process known as amniocentesis. However type 1 that is considered to be the mildest one among them is commonly found.

Symptoms of Osteogenesis Imperfecta

Listed below are the types of Osteogenesis imperfecta according to the grade-

  1. Type I – this is the mildest form of OI that is the commonest too.
  2. Type II – this type is considered to be the most severe one. If affected with this type of OI the child may be born with shorter arms, legs and a softer skull that does not let the newborn survive more than a week or a year.
  3. Type III – this type of OI has almost all the features of type II but their life expectancy is normal.
  4. Type IV – this type of OI can be diagnosed at birth and do not attain fractures until they start walking or crawling.

There are few other types of Osteogenesis imperfecta (OI) but are very rarely found.

CAUSES

This disorder is caused due to genetic abnormality. The affected gene can be passed by any of the two parents. The passed genes due to some spontaneous mutation attains abnormality that causes Osteogenesis imperfecta.

SIGNS AND SYMPTOMS

Symptoms or signs of OI completely depend upon the grade of the disease. However there are some symptoms in common, that includes –

  1. Fragile bone that are more prone to fractures
  2. Weakness of muscles
  3. Joint hypermobility
  4. Curved spine
  5. Malformed or undeformed long bones
  6. Loose joints
  7. Barrel shaped chest
  8. Loss of hearing
  9. Fatigue
  10. Small stature
  11. Soft and mal aligned teeth
  12. Breathing difficulties
  13. Discoloration of sclera (it looks purple, blue or grey)
  14. Discoloured teeth
  15. Triangular shaped face
  16. Deformities of the chest wall (Barrel shaped or pigeon chest)

INVESTIGATION

  1. Physical examination can be done
  2. X Ray – to check for fractured or deformed bones.
  3. DEXA scan
  4. Bone biopsy
  5. Genetic testing

TREATMENT OF OSTEOGENESIS IMPERFECTA

There is not any treatment for the reversement of Osteogenesis imperfecta, however certain measures can be taken for the prevention of further complications. This includes –

  1. Preventive orthopaedic treatment that may consist of  bracing or splinting of several weight-bearing joints like knees, ankles or legs.
  2. Medicinal treatment for better strength of bones.
  3. Dental therapy can also be done as the  teeth are brittle.
  4. Physical therapy can also be taken to provide strength to the bones.
  5. Surgery

COMPLICATIONS

  1. Loss of hearing in adult life (common in type I and Type II)
  2. Heart failure (in Type II)
  3. Respiratory problems
  4. Permanent deformity

AYURVEDIC ASPECT OF OSTEOGENESIS IMPERFECTA

Osteogenesis imperfecta or brittle bone disease in Ayurveda can be correlated to Sahaja Vyadhis that means the genetic disorders. Acharyas believe that the abnormalities in the bones that are Asthi kshaya and Majja kshaya (depletion of bone marrow) are caused mainly due to vitiation of Vata Dosha.

Lakshanas (symptoms) of Asthi Kshaya can be

  1. Hair Fall from scalp or beard
  2. Brittle nails
  3. Weakness and fatigue
  4. Loosening of joints

Lakshanas (symptoms) of Majja Kshaya can be

  1. Degeneration of bones
  2. Weakness

CHIKITSA (TREATMENT)

There is not any specific treatment for treating this disease, only management of the disease can be done to avoid any further complications. This can be done by treating or pacifying the aggravated Vata Dosha and management of the condition can be done accordingly.

HERBAL REMEDIES BY PLANET AYURVEDA FOR OSTEOGENESIS IMPERFECTA

Planet Ayurveda is a GMP certified brand that manufactures herbal supplements. Planet Ayurveda is dedicated to bring the benefits of natural herbs to mankind through some completely natural herbal products that cures diseases without causing any ill effect to the patient.The products manufactured by Planet Ayurveda has no added preservatives or any adulterants.This company exports their products worldwide like to the USA, Europe, Africa and many other countries.  All the products by Planet Ayurveda are manufactured following the ancient Ayurvedic texts under the guidance and supervision of experts of Ayurveda. They have plenty of medicines for various diseases both chronic and acute. Listed are few medicines that improve conditions and manages the symptoms caused by Osteogenesis imperfecta

Product List

  1. Lakshadi Guggul
  2. Bone Support Capsules
  3. Cissus Power Capsules
  4. Boswellia Curcumin
  5. Gandhak Rasayan
  6. Arjun Ghrit

Description of the products that manages Osteogenesis imperfecta well

1) Lakshadi Guggul Tablets

Lakshadi Guggul in the form of tablets by planet Ayurveda shows effective results in  Osteogenesis imperfecta by maintaining both bone and muscle health. Lakshadi guggul consists of Laksha (Laccifer lacca), Arjuna (Terminalia Arjuna), Ashwagandha (Withania somnifera), shuddh Guggul (purified Commiphora mukul) and a lot other herbal drugs that enhances calcium deposition to the bones that even fastens healing a fractured bone too. This product also helps in other conditions like osteoporosis by improving bone density.

Dosage – 1-2 tablets twice or thrice daily with lukewarm water.

2) Bone Support Capsules

These capsules by Planet Ayurveda work well for maintenance of a healthy skeletal system. These capsules consist of the Goodness of  Hadjod (Cissus quadrangularis), Mukta (compound of pearl), Praval pishti (Corallium rubrum) and various other drugs. These ingredients improve the mineral density of bones and make it a better absorbent of calcium. They also strengthen the connective tissues of the bone that prevents it from breaking.

Dosage – 1 capsule twice a day, with plain water after meals.

3) Cissus Power Capsules

These capsules by Planet Ayurveda are made of Hadjod (Cissus quadrangularis) which are rich in vitamin C and help in mineralization and formation of the bones by increasing the strength and density of the bones. These capsules also reduce inflammation and pain in joints. It supports growth of cells and also regeneration of it by preventing loss of bone tissue.

Dosage – 1-2 Capsules twice a day with plain water after meals.

4) Boswellia Curcumin

Boswellia Curcumin Capsules by Planet Ayurveda consist of Shallaki (Boswellia serrata) which is a herb that treats bone diseases by preventing excessive wear and tear of joints. It reduces pain and inflammation of the joints too. Another content of this formulation is Curcumin (Curcuma longa) that helps in building and repairing of the bones.

Dosage –  1 capsule twice a day with plain water after meals.

5) Gandhak Rasayan

These Gandhak Rasayan Capsules are made of extraction of a single component Gandhak better known as Sulphur. Sulphur or Gandhaka helps to treat weak and fractured bones, it helps to make glucosamine and collagen that plays a vital role in maintaining healthy bones and joints. It also protects the cell from damage.

Dosage – 1-2 tablets twice or thrice a day with lukewarm water.

6) Arjun Ghrit

This classical preparation of Arjun Ghrit is mentioned in the classics of Ayurveda. It has Arjuna (Terminalia arjuna), Amalaki (Emblica officinalis), Nagarmotha (Cyperus rotundus) and various other herbs along with Ghee. Arjuna is considered to have bone regeneration properties that help to make healthy bones. All these ingredients also help in improving bone density hence better strength to bones.

Dosage – ½ teaspoon twice a day with warm water or milk.

Contact Planet Ayurveda Support Team to provide you with the costing/ordering and delivery information at – costing.planetayurveda@gmail.com or Call at 0172-521-4040 (India), +91-172-521-4040 (Outside India) or Whatsapp at (+91) 842-749-4030.

CONCLUSION

Here we can conclude that Osteogenesis imperfecta (OI) or brittle bone disease is a genetic disorder of the bone caused due to some abnormality in the gene mutation. This condition can not be reversed and babies who are born with it need to survive with it forever, however certain measures for the management of the disease both by Ayurveda and Modern Science are explained above. Ayurveda considers this condition among the Sahaja Rogas to be genetic disorders and all the symptoms are same as that caused due to aggravation of Vata Dosha so the management is done accordingly. Hence this condition needs to be managed to avoid further complications.

How Can Ayurveda Help You In Healing Fractures Faster?

ABSTRACT

Fracture of bone is a condition in which a patient experiences unbearable pain  and if not cured in the right way can cause major trouble to the patient and can lead to lifetime abnormalities. As our skeleton protects the internal organs and is tough and flexible. It also supports the weight of our body. Hence bones that construct our skeleton provide great stability. Bone fracture is a medical condition in which the constituents of the skeleton i.e bones gets damaged due to external force or by some underlying pathological conditions like osteoporosis, osteopenia, osteomyelitis etc are more prone to fractures. Both Ayurveda and Modern Science explains ample importance of proper healing of a fractured bone in their own ways.

INTRODUCTION

Any break in the continuity of a bone or cartilage, which may be partial or complete can be termed as a fracture. The commonest sites of fracture include wrist, ankle and hip.There are certain reasons that cause fracture which includes trauma like fall from height, road traffic accidents etc. Fractures can also be caused by a few diseases that weaken one’s bone like osteoporosis, osteopenia and a few other conditions that make them prone to fractures.

Fracture

CAUSES

Fractures can be caused by trauma like fall from height, road traffic accidents direct blow or by repetitive forces such as those caused by running or practising a certain sport that causes stress fracture.

SIGN AND SYMPTOMS

The sign and symptoms differ according to the type of fracture if it’s a closed or an opened one.

  1. Swelling
  2. Tenderness
  3. Pain
  4. Deformity of site
  5. Bruising
  6. Redness
  7. Crepitus
  8. Loss of function

TYPES OF FRACTURE

Based upon the type of break

  1. Complete Fracture
  2. Incomplete Fracture

Based on relationship with outside climate

  1. Open Fracture
  2. Closed Fracture

Based on the Pattern

  1. Transverse
  2. Spiral
  3. Compound
  4. Longitudinal

Specific type of fractures –

  1. Greenstick
  2. Comminuted
  3. Impacted

DIAGNOSIS

IMAGING TESTS

  1.  Physical examination
  2. X Ray – For finding out the exact location and extent of fracture.
  3. CT Scan/ MRI – It helps to visualise fracture, bleeding and soft tissue damage.

LAB TESTS

  1. CBC (Complete Blood Count)- To find out if hematocrit is increased or decreased.
  2. Coagulation profile – It alters due to blood loss and hence should be checked.

MANAGEMENT

Management of fracture includes

  1. Emergency Care– It includes -rest of the site by splinting, next is ice therapy followed by compression and elevation to reduce swelling.
  2. Definitive care-
  3. Reduction – It can be done:

(a) Closed reduction- its initial and standard method of reduction.it can be done under conscious sedation.
(b) Open reduction – it’s done if the closed reduction fails to reach the need, its done surgically.

  1. Immobilisation
  2. Traction
  3. Splinting
  4. Rehabilitation – It consists of joint mobilisation, gait training etc. it’s done to prevent stiffness.

COMPLICATIONS

Early complications

  1. Shock
  2. Fat embolism
  3. Deep vein thrombosis
  4. Infections

Late complications

  1. Delayed union (slower production of new tissue)
  2. Non-union(body’s inability to heal fracture)
  3. Mal union(occurs when fractured bone heals in an abnormal position)

AYURVEDIC ASPECT OF FRACTURE (ASTHI-BHAGNA)

In Ayurveda, fracture can be correlated with bhagna. When the continuity of asthi(bone) is broken partially or completely can be termed as asthibhanga or asthibhagna. According to ayurvedic Scriptures Bhagn includes both asthibhagna (fracture) and sandhibhagna (Dislocation) under bhagna.

NIDANA (CAUSES)

According to Ayurveda and in modern Science there are no such differentiations about the cause or nidana of bhagna. It is same as mentioned above like-

  1.         External trauma
  2.         Intrauterine fracture
  3.         Indirect trauma
  4.         Pathological reasons- in patients of tuberculosis.

BHEDA (TYPES OF BHAGNA)

Acharya Sushruta explains two types of bhagna, there are

  1. Savrana bhagna (Open fracture)
  2. Avrana bhagna (Closed fracture)

Another type is

  1. Apurna bhagna (Incomplete fracture)
  2. Purna bhagna (Complete fracture)

1. APURNA BHAGNA

As the name itself says that in this type of bhagna the asthi i.e bone doesn’t separate into fragments. It can be correlated to incomplete fracture in modern.

Apurna bhagn is further divided into

  1.  Picchit (depressed) bhagna- Bone fragment is displaced from its anatomical position as seen in injury of head.
  2. Vakra (Green stick) bhagna- as explained above in the modern aspect its commonly seen in children.
  3. Sphutit (fissured) bhagna- there are cracks in bone but the fragments aren’t displaced.
  4. Chinna bhagna

2. PURNA BHAGNA

In this type of bhagna, the bone fragments are completely separated from each other. This type is further divided into-

  1.  Apatit (transverse)
  2.  Kanda (oblique)
  3.  Ashwakarna (spiral)
  4.  Majjanugata (Impacted)
  5.  Patit (comminuted)
  6.  Karkatak (Multiple)

All the above-mentioned types are the same as mentioned in the modern aspect.

LAKSHANA OF BHAGNA

LOCAL

  1. Deformity
  2. Abnormal mobility
  3. Loss of function
  4. Discoloration & tenderness

GENERAL

  1.  Shock
  2. Aseptic traumatic fever

UPDRAVA (COMPLICATIONS OF BHAGNA)

Acharya Sushruta mentioned that complications of bone injury could be local or systemic. Local complications like mal union or non union. Even tight bandaging can lead to swelling , pain or even  avascularization that can lead to gangrene. Systemic complications can be fever, abdominal distention and a few others.

SADHYASADHYATA (PROGNOSIS)

  • Acharya Sushruta described the prognosis of fracture into three categories which are Sukh sadhya (easily curable), kasht sadhya(cured with difficulty) and asadhya (incurable)
  • Sukhsadhya- Acharya Sushrut explained that patients fractured during balyakala (childhood) or with a minor crack or a hairline fracture can be managed without difficulty.
  • Acharya Sushruta also mentioned about the importance of ritu for healing a fractured bone, he said fractured bone heals better in shishir ritu.
  • Kashtsadhya – Healing can be difficult if the type of fracture is of comminuted (churnit), incomplete (chinna), impacted (majjanugata).
  • Asadhya – Churnit (comminuted) bhagn of frontal or iliac bone, complete fracture or dislocation of pelvic bone also fracture of temporal bone, septum or vertebral column can be asadhya.
  • Acharya Sushruta also explained the importance of post treatment care of the bone and said that even after proper treatment the fractured bone may not unite in the right way as it should if displaced improperly during immobilisation period or even by improper bandaging. All these factors can lead to failure of treatment.

AYURVEDIC LINE OF TREATMENT

The ancient Ayurvedic texts describes chikitsa of asthi bhagna and categorised it into general management, specific management according to the type & site of fracture and described about the Pathya & apathya (do’s and don’ts) as according to Ayurveda the Pathya & apathya plays a major role in healing. General chikitsa of bhagn includes Anchan(traction), Pidana (manipulation by local pressure), Sanshipt (stabilise) and Bandhana(immobilisation). All these four principles of management of fracture explained by Sushruta are adopted today by the Modern Sciences too.

  • Kushabandhana or splint explained by Acharya Sushruta has a soft sheath- like surface that  provides support to the fractured bone.
  • Alepa or paste of lal chandana or Shata dahuta Ghrita (100 times washed ghee) can be used.
  • Timing of bandhana or bandaging plays a crucial role, in saumya ritu(winters) bandaging should last for 7 days, in normal temperature for 5 days and during agneya ritu (summers) for 3 days.

MANAGEMENT OF SPECIFIC TYPE OF FRACTURE

Ayurveda has a vast explanation of treatment of different types of fracture depending upon its site, here are a few common sites and treatment of fractures.

  1. In fracture of tibia , fibula or femur traction should be applied carefully along the direction of bone after a gentle massage by using Ghrita (Ghee). A fractured arm should also be treated the same way.
  2. In case of dislocation of the shoulder joint, the axilla should be raised and bandaged the part by swastika bandha(figure of eight) should be done.

HERBAL REMEDIES BY PLANET AYURVEDA FOR EARLY HEALING OF FRACTURES

Planet Ayurveda is a GMP-certified company offering products worldwide that shows extreme results. All the products are prepared by following the ancient Ayurvedic texts and using natural ingredients under the guidance of MD Ayurveda experts.The main goal of the company is to eliminate the source of any disease and provide a healthy life to mankind. All the products are completely safe and devoid of any kind of adverse effects.

Herbal Supplements for Fractures

Herbal Supplements for Fractures

  1. Lakshadi Guggul
  2. Cissus Power Capsule
  3. Ashwagandhadi Ghrit
  4. Bone support Capsules
  5. Dashmoola Capsules

1. LAKSHADI GUGGUL

Lakshadi Guggul from Planet Ayurveda is a combination of herbs that helps to pacify the vata dosha from the body which ultimately increases the level of asthi. This will help in improving bone health and hence the fracture will heal in a better way. It contains  Laksha (Laccifer lacca), Asthisamharaka (cissus quadrangularis), Arjuna (Terminalia arjuna) and various other herbal drugs combined in the form of tablets.

Dosage– 1-2 tablets twice or thrice daily with lukewarm water.

2.  BONE SUPPORT CAPSULES

Bone Support capsules by Planet Ayurveda helps in regaining natural bone mineral density of bones which ultimately helps in better healing of the fractured bone. It’s a great blend of- Shudh Laksha (Laccifer lacca) , Suhanjana Beej (Moringa oleifera)- which is rich in calcium and helps in bone strengthening , Praval pishti (Corallium rubrum) which too is rich in calcium, Mukta (Compound of pearl calcium)etc. As the name signifies itself, it provides better support and is also known to increase the bone mineral density if taken properly.

Dosage –1 capsule twice a day

3.  ASHWAGANDHADI GHRIT

Ashwagandha Ghrita by Planet Ayurveda supports muscle mass, relieves stress, and improves energy, strength, and vitality that excellently helps the bones too. It also helps in reducing fatigue especially caused by pain due to fractures. Its components are- Ashwagandga (Withania somnifera), Vibhitaki (Terminalia bellirica), Go Ghrita (cow’s Ghee), Go Dugdha(Cow’s milk) which acts as vata dosha pacifiers.

Dosage– 3-6 gms mixed with mishri.

4.  CISSUS POWER CAPSULE

Cissus power capsules from Planet Ayurveda are formed of dried Hadjod (Cissus quadrangularis).  Hadjod which helps in the building and functioning of bones is a major constituent of Cissus Power Capsule.Thus helpful in healing fractures.

Dosage– 1-2 capsules twice a day with water.

5.  DASHMOOLA CAPSULE

Dashmool means the roots of 10 herbs, so here special roots of 10 different plants are combined to prepare the capsules. It contains herbs such as Bilwa (Aegle marmelos), Shyonak (Oroxylum indicum), Agnimantha (Clerodendrum phlomidis), Gambhari (Gmelina arborea), Kantakari (Solanum surattense), Brihati (Solanum indicum), Prishnaparni (Uraria picta), Shaalparni (Desmodium gangeticum) and various other drugsare being used.This capsule is very effective in calming the vata dosha, thus reduces pain. Bilwa is used in fractures for wound healing. Shyonak is used as a antispetic. Patla is used for its anti-inflammatory properties. Agnimantha is useful in cases of swelling and inflammation. Gambhari is useful for reducing pain and Shaalparni has an antipyretic property.

Dosage– 1-2 capsules twice daily with plain water after meals.

CONCLUSION

We can conclude that the description of fractures and its management explained by Acharya Sushruta and modern medical Science are a lot similar from each other. Basically the concept and principle of approach remains the same from ancient to till date, like ‘Bandha’ by Acharya Sushruta is explained by ‘Bandaging’ in Modern Sciences, Savrana- Avrana as open-closed fracture and many more. Ayurveda has given ample importance to Asthi Sharira also explained it pathya-apathya (do’s & don’ts) of bhagna. Such immense knowledge clearly states the understanding and far sightedness of our Acharyas as their principles and managements are still applicable in today’s era with tremendous efficacy.