Category: Irritable Bowel Syndrome

Mesalamine Side Effects and Better Options in Ayurveda to Replace It

ABSTRACT

Gut health and digestion are considered as the most important processes of the human body. Anything that hampers the process of digestion and elimination disturbs the basics of the entire body. Inflammatory bowel disease or disorders are a group of disorders that cause chronic inflammation of the tissues of the digestive tract. In this article, we will look at IBD, modern treatment of mesacol in IBD and the better safer alternatives of mesacol by Ayurveda.

INTRODUCTION – WHAT IS IBD?

IBD or Inflammatory bowel disease is a group of disorders that cause prolonged inflammation of the digestive tract and majorly affects the most active period of one’s life i.e. 20-30 years of age.

Ulcerative Colitis and IBD

The two most common one are

1. Ulcerative Colitis

This condition involves inflammation and formations of sores/ulcers in the large intestine, colon and rectum. This is more common in males.

2. Crohn’s Disease

This type of IBD can affect the entire digestive tract (from mouth to anus) and causes inflammation penetrating into the deeper layers of the digestive tract. This kind is more common in females.

COMMON SYMPTOMS IN IBD

  1. Bloody Diarrhea
  2. Weight loss
  3. Tenesmus
  4. Urgency
  5. Fatigue
  6. Weight loss
  7. Night Sweats

COMMON CAUSES OF IBD

The exact cause is unknown however these factors are found to play a role in the occurrence of IBD

  1. Smoking
  2. Overactive Immune system
  3. Family History
  4. Excessive consumption of NSAIDS and antibiotics
  5. Consumption of highly saturated fats.

DIAGNOSIS OF IBD

Your physician may refer you to a gastroenterologist, who may then order some tests such as:

  1. Stool test
  2. Colonoscopy and Biopsy
  3. MRI & CT

TREATMENT AS PER MODERN METHODS

  1. Corticosteroids
  2. Aminosalicylates
  3. (MESALAMINE)
  4. Thiopurines
  5. Immunomodulators

In this article, we will take a deeper look into a kind of Aminosalicylates called Mesalamine (also known as mesalazine).

WHAT IS MESALAMINE?

Mesalamine (also called mesalazine), is an anti-inflammatory drug that is used to treat the inflammation of the digestive tract caused by ulcerative colitis, Crohn’s and inflammatory bowel disease. It works by suppressing the chemical messengers called prostaglandins that cause inflammation of the intestine. This reduces ulceration, bleeding, flare-ups of the IBD. Mesalazine is sold under the brand name Mesacol which is a common prescription drug given by doctors. Mesacol (mesalazine) is majorly used in patients of Ulcerative colitis.

SIDE EFFECTS OF MESALAZINE (also called as Mesalamine)

While there are many benefits of Mesalamine (also known as mesalazine), long term usage can result in certain side effects of mesacol. Let us take a quick look at the side effects caused by the medicine mesacol:

  1. Flatulence
  2. Headache
  3. Vomiting
  4. Dyspepsia
  5. Rashes
  6. Nausea

Long Term usage can cause

  1. Worsening of colitis
  2. Renal toxicity
  3. Hypersensitivity reactions

AYURVEDA PERSPECTIVE ON INFLAMMATORY BOWEL DISEASE

Ayurveda, a 5000 year old holistic system of medicine from India considers IBD as PITTATISARA and RAKTA ATISARA. When the digestion is hampered and there is formation of AMA in the body, it leads to the accumulation of toxins in the intestine and eventually leads to the vitiation of Pitta. Post this, when the blood in the intestine or the GI tract is vitiated by Pitta, it leads to the inflammatory change that leads to diarrhea and bloody stools. When the Pittaja Atisara is not treated, it eventually leads to Raktaja Atisara.

CAUSES AS PER AYURVEDA

As per Ayurveda, the causes for IBD are

  • Consumption of excess spicy, sour foods.
  • Consumption of heavy, raw products.
  • Irregular eating habits
  • Smoking and alcohol consumption.

AYURVEDA TREATMENT

Ayurveda treatment has a holistic approach that majorly focuses on the root cause. The treatments used are aimed at pachan (Digestion, Agni deepana (Increasing the metabolism), Vrana Ropana (to heal the ulcers) and Stambhana (to stop diarrhea). The commonly used herbs are Dadima (Punica granatum), Kutaj (Holarrhena antidysenterica), Bilwa (Aegle marmelos), Chitrak (Plumbago zeylanica) and vasa (Justicia adhatoda). All these herbs are herbal alternatives to mesacol (also called mesalazine). Along with the shaman treatment (oral), certain procedures can also be done in Shodhana treatment (Panchakarma procedures) such as Vaman, virechana and pittahar vasti, nabhi lepa and shirodhara.

AYURVEDA DIET PATHYA AND APATHYA (Dos and Don’ts)

Along with the medicines, Ayurveda also recommends a strict diet with certain do’s and don’ts that help in the complete recovery from IBD and prevent remission.

1. PATHYA (Dos

These are the things you should add in your diet.

  1. Ghee
  2. Curd
  3. Banana, Apple, Bel and papaya
  4. Bottle gourd and ash gourd
  5. Turnip, radish, carrots

2. APATHYA (DON’T’S)

These are the things that you should avoid in your diet

  1. Spices like red chilli, black pepper.
  2. Processed packed food.
  3. Dairy products
  4. Non vegetarian products
  5. Kidney beans, chickpeas and black gram

HERBAL ALTERNATIVES OF MESALAMINE BY PLANET AYURVEDA

Planet Ayurveda, a GMP certified company, prepares pure ayurveda formulations which are safer alternatives as compared to mesacol or mesalazine (Mesalamine). Planet Ayurveda prepares 100% pure, preservative free products .Ayurveda texts have some of the best alternatives to mesalazine (mesacol). All the ingredients in the products are aimed at providing healthy intestines and balance of the tridoshas.

The Ulcerative Colitis Care Pack includes

  1. Capsule Arjuna
  2. Vatsakadi Churna
  3. Pitta Balance
  4. Kutajghan Vati

Alternative Medicines for for Ulcerative Colitis, IBD, Crohn's Disease

Herbal Remedies for ulcerative colitis

PRODUCT DESCRIPTION

1. Arjuna Capsule

Arjuna Capsules are prepared with standardized extract of Arjuna herb (Terminalia Arjuna).This formulation is soothing, nurturing and healing. Arjuna herb is cardio protective but also helps in relieving the gastric issues and burning sensations which is why it is useful in ulcerative colitis. It is also anti allergic and anti oxidant which also helps in dealing with all kinds of body pains, swelling and ulcers.

Dosage: 2 capsules twice daily after meals.

3. Vatsakadi Churna

Planet Ayurveda’s Vatsakadi Churna is a potent and safe formulation that has a combination of various herbs. The prime ingredients of this formulation are Kutaj (Holarrhena antidysenterica) and Bilwa (Aegle marmelos) which are great for anti dysenteric action and also helps in reducing the inflammation in the body which makes this formulation a prime choice for IBD issues.

Dosage: 1 tsp twice daily after meal with plain water

3. Pitta Balance

A vegetarian capsule by Planet Ayurveda made with Pitta balancing herbs with the purest extracts of the ayurveda herbs. This capsule will support digestion, maintain the intestinal mucosa. It is made with Praval pishti, mukta pishti and kamdudha ras. This formulation provides a cooling effect to the body and helps in dealing with ulcers. This herbal formulation helps in balancing the aggravated Pitta from the body which makes it a perfect choice for IBD.

Dosage: 1 capsule twice daily after meal with plain water.

4. Kutajghan Vati

Kutajghan Vati is a tablet formulation made from the classical Ayurveda texts with the prime ingredient as Kutaj herb. Kutaj (Holarrhena antidysenterica) as an herb has cold potency and pacifies Pitta and Kapha dosha both of which are aggravated in IBD cases. It also has dry nature with astringent taste and helps remove ama (toxins) from the body.

Dosage: 2 Tab twice daily after meal with plain water

CONCLUSION

To achieve a healthy body, every individual needs to have proper digestion and elimination. Disorders like IBD can affect these processes and thus the normal lifestyle. While one can always go for modern treatment but considering the side effects of mesacol (which contains mesalazine/Mesalamine), there are much safer ayurveda alternatives to mesalazine. These herbal alternatives along with diet and lifestyle corrections help in dealing with inflammatory bowel disease and associated complications.

Low FODMAP Diet & Herbal Remedies for IBS Treatment

Abstract

Low FODMAP stands for fermentable, oligosaccharides, disaccharides, monosaccharides, polyols which are the short chain of sugar that are poorly digested by the body. They are found in many natural foods and these foods show symptoms like gas, bloating, abdominal pain. This diet is planned for patients who are suffering from IBS (irritable bowel syndrome), SIBO (Small intestinal bacterial growth), and GI Disorder.  Is a functional disorder of the small intestine which is followed by altered bowel habits lasting from weeks to months. Stress, anxiety and a hectic schedule plays an important role which worsen the situation. In ayurveda this is similar to grahani. Let’s discuss this in detail!

INTRODUCTION

FODMAPs are short chain carbohydrates and sugar which is poorly digested by the body, as they ferment into large intestines during digestion which produces carbon dioxide, hydrogen, which causes the intestine to expand and produce symptoms like pain and bloating, they are common in patients suffering from IBS. So, they are on a recommended low FODMAP Diet, this is given to patients to heal the gut. IBS causes great distress to patients and they become fatigued. Patients who include a low FODMAP diet may get relief from symptoms such as migraines, fibromyalgia, eczema. Anxiety, stress, and food habits give rise to IBS. In ayurveda it is known as grahani where there is alteration in bowel habits. There is alteration in stools habit; it may be occasionally soft or hard. CLASSIFICATION – IBS D- Where diarrhea is the main symptom, IBS C- With constipation, IBS A- Alternate constipation and diarrhea.

Irritable Bowel Syndrome

FACTS ABOUT IBS

  1. Worldwide it is estimated that 5-10% of the population suffers from IBS.
  2. Mostly it is more common in patients above 50 years.
  3. 20-40% of patients visiting gastroenterologists are due to IBS.
  4. IBS is unpredictable, symptoms may vary from person to person.
  5. Exact cause of IBS is not known but it is due to change in normal bowel movements and its sensation.

CAUSES AS PER AYURVEDA

  1. Excessive fasting
  2. Improper food
  3. Heavy intake of food
  4. Junk food
  5. Improper virechana (purgation)
  6. Grief
  7. Shock
  8. Rectal bleeding
  9. Anemia
  10. Recurrent

PRODROMAL FEATURES

  1. Nausea
  2. Digestion is delayed
  3. Fatigue
  4. Bloating
  5. giddiness
  6. Gurgling sound in stomach
  7. Vomiting

On the basis of doshas

  1. Vataja grahani- Abdominal stools, flatus, headache, chest pain.
  2. Pittaja grahani- Burning sensation, belching
  3. Kaphaja grahani- Heaviness is felt on abdomen, mucus is present in stools, sensation of incomplete defecation.
  4. Sannipatja grahani- Here all the three doshas are involved, so there is lack of concentration, headache, flatus, chest pain.

TESTS FOR IBS

To examine IBS, doctors recommend certain stool tests to check the certainty of infection.

Diagnostic procedure which are followed:

  1. Colonoscopy
  2. X-ray, CT scan
  3. Upper endoscopy

Certain laboratory test

  1. Lactose intolerance test
  2. Stool test
  3. Breath test for bacterial overgrowth.

Treatment of IBS focuses on relieving symptoms

  1. Avoid food which trigger the symptoms (caffeine, spicy, alcohol)
  2. Drink more amount of water
  3. Enough sleep
  4. More fiber
  5. Gluten free diet
  6. Low FODMAP diet is very beneficial

FODMAP DIET

These are carbohydrates which stands for Fermentable, Oligosaccharides, Disaccharides, Monosaccharides, Polyols. Oligosaccharides such as wheat, rye, nuts, legumes, garlic. Disaccharides such as lactose containing products such as milk, yogurt, ice cream. Monosaccharides such as fructose containing foods such as honey, agave. Polyols low calorie sweeteners as in mint. This diet is recommended in patients who suffer from IBS and other digestive problems. FODMAP is found in some food naturally or in fruits and vegetables, are healthy probiotics which help the bacteria to grow in the gut, FODMAP are not digested in the small intestines but they increase the fluid in large intestines. This diet may relieve the problem in people who suffer from IBS. FODMAP is given to improve the symptoms for 4-6 weeks after that it is reintroduced to avoid food identifying the cause, LOW FODMAP is nutritionally balanced.

LIST OF FOODS THAT ARE EFFECTIVE

  1. Vegetables (carrot, green beans, lettuce, tomato, ginger, olives, turnips).
  2. Fresh fruits (oranges, grapes, banana, lime, strawberries)
  3. Soya including tofu, tempeh
  4. Grains ( rice, oats, corn flour, gluten free pasta).
  5. Non dairy products- almond milk, rice milk, coconut milk.
  6. Probiotics are helpful in patients of IBS as bacteria get introduced and show their beneficial effects.
  7. Seeds as in pumpkin, sesame sunflower seeds.
  8. Oils such as coconut and olive oil.

AVOIDED DIET

  1. Some vegetables like onion, garlic, cabbage, broccoli, sweet corn, celery.
  2. Fruits such as peaches, apricots, mangoes, blackberries.
  3. Beans and Lentils
  4. Pasta, Pizza, and various dairy products such as custard, pudding, ice cream, cottage cheese.
  5. Sweetener such as honey, sorbitol, isomalt (found mainly in cough syrups)
  6. Drinks such as alcohol, coconut water.
  7. In patients of IBS some foods are avoided as they alter the function of muscles such as caffeine they cause muscle contractions.

BENEFITS OF LOW FODMAP DIET

It reduces the digestive symptoms – As IBS include stomach pain, bloating and bowel urgency and low fodmap decreases pain and bloating. As there is higher chances that upto 80% relieve stomach pain, manages diarrhea, constipation

Improves quality of life- It improves digestive symptoms as it reduces fatigue, stress and boosts up happiness and vitality.

HOW TO FOLLOW LOW FODMAP DIET

STAGE 1 – Restriction- Patients should avoid high fodmap diet. 75% patients show improvement in 6 weeks and get relief from digestive symptoms.

STAGE 2- Reintroduction- This is reintroducing a high fodmap diet after 6-7 weeks, so that it is easy to find out the people who are sensitive to which carbohydrate or food. The patient is strictly on a low diet for 2-3  days and waits before reintroducing.

STAGE 3 – Personalization – This is a low modified fodmap diet as we restricted some fodmap nuts when reintroduced showed well tolerance . This improves gut health and quality of life.

AYURVEDIC MANAGEMENT

  1. Regular intake of buttermilk.
  2. Pomegranate
  3. Proper sleep
  4. Fiber rich diet is very useful

Panchkarma plays an important role in IBS as it treats stress and depression such as

SHIRODHARA– This procedure of pouring of medicinal liquid over the forehead is very useful.

PRANAYAM is useful for lifestyle management such as Yoga, moderate exercise, and stress management.

In ayurveda stress is due to imbalance of doshas, so medication, massage, aromatherapy is helping to reduce the symptoms of IBS.

SOME OF THE DRUGS USED IN IBS

1. Turmeric

Turmeric is a great medicine for digestion, abdominal pain, and bloating. It has the property of anti-inflammatory and antioxidant agents. Turmeric is used to retard the facial hair growth as it is applied over face for 15 minutes and than remove it. Haridra has ushna veerya so it enables free circulations and nutrients to every cell of the body. It removes the blocked channels which are created by pitta dosha and kapha dosha.

2. Plantago Psyllium

Commonly known as isabgol a high rich fiber diet used for treatment in piles, constipation, herpes, distension of abdomen. Psyllium has madhur (sweet)  taste, snigdha (moisture) guna, sheetal veerya and it reduces vata dosha. Isabgol acts against constipation by trapping the water in the colon and acts as a laxative.

HERBAL REMEDIES FOR IBS BY PLANET AYURVEDA

Planet ayurveda is one of the certified companies which formulates their own herbal products for managing health concerns. The products  formulated here are free from any preservatives, color, and any synthetic material. The herbal products prepared here are free from any side effects and are totally safe made under strict guidance of the managing team. For the purpose of IBS, planet Ayurveda provides an IBS PACK we are going to discuss here.

Herbal Supplements for Irritable Bowel Syndrome

Herbal Supplements for Irritable Bowel Syndrome

IBS CARE PACK

1. Pitta Balance

It is the formulation of planet ayurveda containing Jahar Mohra pishti (natural calcium compound), Akik pishti (natural calcium compound), Giloy (Tinospora cordifolia). Pitta imbalances produce symptoms mainly in the stomach and intestines. Ghee mitigates pitta and increases digestion strength. Purgation therapy targets the small intestines which is the main site of pitta. Consuming milk decreases pitta dosha as it is a natural coolant.

Dosage– 1 capsule twice daily with plain water after meals

2. Kutajghan vati

Kutajghan vati is found in the forms of tablets, which helps to maintain healthy digestive system, supports intestines, this herb is free from any preservatives, colors, fillers and one of the formulations of planet ayurveda which contains Kutaja (Holarrhena antidysenterica). Kutaj is a potent herb used as stanya shodhana, asthapanopaga, and a very good drug to cure atisara, pravahika.

Dosage– 1-2 tablets twice daily with lukewarm water.

3. Digestion Support

Digestion support is herbal formulation without any chemicals, is a blend of unique herbs which are helpful in the digestive system, maintaining the pH in the stomach. This is one of the formulations of planet ayurveda which mainly has Amla (Emblica officinalis), Haritaki ( Terminalia chebula), Dhania (Coriander sativum) and many more. Amla is one of the useful herbs which has rejuvenate properties, Haritaki is a useful herb for relieving gas as it suppresses the formation of gas and acts as a mild laxative.

Dosage– 1 capsule twice daily with warm water after meals.

4. Sanjivani vati

This is One of the formulations which is found in the form of tablets and used by acharya in ancient times for treatment of many diseases. It is formulated by planet Ayurveda which consists of  Vidanga (Embelia ribes), Pippali ( Piper longum), Vacha (Acorus calamus),and many more. Sanjivani vati is commonly known as amrit vati. Sanjivani vati is a powerful herb which cures aam and balances vata and kapha dosha and increases metabolic fire and burns out fats and toxins from the body. Sanjeevani vati acts as an antivenom and antitoxin drug.

Dosage– 1-2 tablets twice daily with lukewarm water.

CONCLUSION

Here we studied IBS (irritable bowel syndrome) which is a functional disorder of the small intestines which is characterized by abdominal pain, bloating, and altered bowel habits. Is a functional disorder of the digestive system leaving patients in stress and fatigue. Here we discussed types, causes, and about ayurvedic management of this disease and diet which is consumed in the IBS (low fodmap) diet and many herbal remedies which are formulated by planet ayurveda (IBS care pack) which provides much relief to patients .