Category: Health Benefits

Glanzmann Thrombasthenia Symptoms, Causes And Treatment By Ayurveda

Abstract

Platelets are essential for proper blood clotting. Any deformity in their production and functioning is a serious problem. Glanzmann Thrombasthenia is a congenital bleeding disorder that occurs due to the impaired functioning of platelets. This is inherited from the parents to the child, with an equal risk of having the disorder in both male and female children. This disorder is mainly seen in populations that practice intermarriages. In this article, we will be discussing various causes and symptoms of Glanzmann Thrombasthenia. Also, we will discuss the ayurvedic treatment for this disease.

Glanzmann Thrombasthenia

Introduction

Glanzmann Thrombasthenia is a rare but serious platelets disorder in which there is abnormal bleeding from different parts of the child. The symptoms begin at birth or shortly after some time of the child’s birth. There is difficulty in getting blood to clot and the child becomes bruised or loses a large quantity of blood. This is an autosomal recessive condition and both parents need to have an abnormal gene in order to inherit it into their child. Untreated Glanzmann Thrombasthenia can lead to hemorrhages which may be a life-threatening condition.

Ayurvedic Aspect

We can correlate Glanzmann’s Thrombasthenia with “Raktapitta” in Ayurveda. Raktapitta is a hemorrhagic disorder in which bleeding occurs from various parts of the body. The bleeding disorders according to Ayurveda occur due to an imbalance of tridosha and excess accumulation of Pitta dosha. This excessive pitta dosha contaminates the rakt (blood), which also toxicate the blood channels throughout the body. The Pitta dosha along with Vata and Kapha dosha causes the oozing of blood from the openings of the body that are characterized accordingly.

 Causes

  • Glanzmann Thrombasthenia occurs due to the lack of protein (Fibrinogen) that is on the surface of platelets.
  • The protein is essentially needed to join/clump the blood cells together. The absence of protein causes this disease. This lack of protein is caused due to various genital abnormalities and mutations.
  • Autoimmune diseases
  • Certain infections
  • Leukemia

The cause of Raktpitta according to Ayurveda are

  • Pitta dosha vardhak Aahar and Vihar
  • Excess anger
  • Consuming Katu (spicy), lavana (Salty), and amla (Sour) is excess in diet.

Symptoms

Symptoms of Glanzmann Thrombasthenia include abnormal Mucosal bleeding from different body parts in the child at birth or shortly thereafter birth. The infant tends to bruise easily with the following symptoms.

  •  Gastrointestinal bleeding (bleeding anywhere in the GI tract)
  •  Gingival bleeding (bleeding from gums)
  •  Epistaxis (Nose bleeding)
  •  Petechiae
  •  Purpura
  •  Hematuria (Blood in urine)
  •  Bleeding after or during surgery

Women with this disorder have

  •  Menorrhagia
  •  Abnormal uterine bleeding

Diagnosis

The diagnosis is ruled out for proper finding of the disorder

  •  Complete blood count
  •  Platelet count
  •  Bleeding time
  •  Clotting time- Prothrombin time test
  •  Platelet aggregation study
  •  DNA analysis
  •  Prenatal analysis
  •  Blood protein deficiency test
  •  Genetic tests

Treatment

The standard treatment followed in Glanzmann Thrombasthenia is

  • Blood platelet transfusion (throughout life)
  • Bone marrow transplantation
  • Hormonal therapy
  • Symptomatic treatment-
  • Nasal packaging (in nose bleeding)
  • Dental care (in gums bleeding)
  • Antifibrinolytic agents (in GIT bleeding)
  • Genetic counseling
  • Surgery

Herbal remedies for Glanzmann Thrombasthenia by Planet Ayurveda

Planet Ayurveda provides pure forms of medications that effectively manage the condition without any delay or side effects. Proper medications and doses are to be consumed as directed by the doctors of Planet Ayurveda. The medications are manufactured very carefully for the consumption of children. They are pure herbal extracts with no added chemicals that may affect the immunity and health of your child. The priority medications used in Glanzmann Thrombasthenia by Planet Ayurveda are

Product List

1. Immune Booster

2. Giloy Ghan Vati

3. Kumar Kalyan Ras

4. Swarn Vasant Malti Ras

5. Green Essentials

6. Punarnava Mandur

7. Spirulina Capsules

Herbal Remedies For Glanzmann Thrombasthenia

Herbal Remedies For Glanzmann Thrombasthenia

Products Description

1. Immune Booster

Immunity booster is an herbal preparation prepared from Grape seed (Vitis vinifera), Bhumi amla (Phyllanthus niruri), Amalaki (Phyllanthus emblica), etc. These tablets rebuild the whole immune system by strengthening immunity and eliminating all toxins/ailments from the body of the child and recovering general health by easing the symptoms of this bleeding disorder.

Dosage  Have 2 capsules twice daily

2. Giloy Ghan Vati

The giloy ghan Vati is prepared from Giloy (Tinospora cordifolia) and is used to maintain the normal levels of tridoshas in the body. These natural tablets effectively maintain the healthy tissues and blood cells in the body that keep the child healthy.

Dosage  Have 2 Vatis twice daily

3. Kumar Kalyan Ras

This is an herbal ayurvedic formulation having a mixture of wonderful herbs used effectively for the maintenance of general health and overall immunity of the child. It contains Kumari ras (Aloe vera), Bhasma (Calx) of Parada (mercury), Swarna (Gold), Makshik (Copper), Abhraka (Mica), Loha (Iron), etc. mainly it is prescribed in pediatric disorders (disorders in children). The medicine is indicated to be taken with guidance from an Ayurvedic Doctor.

Dosage  One tablet to be chewed twice daily

4. Swarn Vasant Malti Ras

This is a dietary supplement for the maintenance of healthy body immunity and normal temperature of a child that contains Bhasma (Calx) of Gold and Mukta, etc. These supplements balance Vata and Kapha dosha and support healthy respiratory functioning.

 Dosage  One tablet to be chewed twice daily

5. Green Essentials

These essential capsules are prepared from Grape seed (Vitis vinifera), Wheatgrass (Triticum Aestivum), Green tea (Camellia sinensis), etc. This natural product supports a healthy immune system and helps to maintain the overall health of the person. These capsules are known to have various health benefits due to their superfood ingredients. Consuming these essentials on a regular basis eases the symptoms of Glanzmann’s Thrombasthenia.

Dosage  Have 2 capsules twice daily

6. Punarnava Mandur

These tablets are the classical formulations of Planet Ayurveda helpful to improve blood count, and blood quality and removing toxins from the body through urine or sweat. These tablets contain Punarnava (Boerhaavia diffusa), Chavya (Piper chaba), Mandoor Bhasma (Ferric oxide calx), etc. These tablets reduce the inflammation in the child and also reduce the risk of disorders that have maximum chances to occur in a newborn such as jaundice, pedal edema, Glanzmann’s Thrombasthenia, etc.

Dosage  Have 2 tablets twice daily

7. Spirulina Capsules

These tablets contain Spirulina which is the powerhouse of many health benefits. It is a natural multivitamin supplement that removes all ailments from the body. It improves stamina, eyesight, hemoglobin levels, and energy levels in the body. These tablets are stuffed with a lot of micronutrients that have strong antioxidant and immune-boosting properties.

Dosage  Have 2 capsules twice daily

CONTACT PLANET AYURVEDA TO PROVIDE YOU THE COSTING / ORDERING AND DELIVERY INFORMATION AT – COSTING.PLANETAYURVEDA@GMAIL.COM OR CALL AT +91-172-5214040

Conclusion

Thus we can conclude that Ayurveda medicines are efficient enough to maintain immunity and help overcome many bleeding disorders in children. Our talented doctors prescribe the required medication to the children after analyzing each aspect and possibility. Our medicines are 100% pure and do not have any side effects. For more queries contact us at www.PlnaetAyurveda.com

 

Relation of Hemapheresis with Raktashodhana in Ayurveda

Abstract

Hemapheresis is the collection of blood components or the removal of the parts of blood using automated equipment. We will tell about the process, indications and how this is related to ayurveda and certain medications of this disease. In this method rakt shodan is done to detoxify the impurities. And certain other procedures of panchkarma are done to remove the impurities and  herbs are also provided that we will discuss further.

Hemapheresis

Introduction

Hemapheresis is the therapeutic plasma exchange (TPE) which involves removing blood from the donor. In this particular part of blood such as plasma and platelet is removed, and removing part then it is returned to the bloodstream of the patient and donor. TpE is a safe procedure and well tolerated. Death is rare 0.1% of all procedures. It is the unilateral paresis , the weakness of the one side of the body. In this various processes are done like erythrocytapheresis , plasmapheresis, plateletpheresis.

Process of Hemapheresis

Hemapheresis involves the direct blood into the donor veins through tubing to a machine which separates blood and its components. This procedure is generally centrifugation. After this separation the desired component is removed and the other is reinfused into the patient. This is a painless procedure and 2 hour time is required for this process. There are four centrifugation variables- the first variable is the speed and bowl diameter, the second is sit time, in the third solutes are added and the fourth is plasma volume and cellular content.

There are various categories of collection of component

  • Plasmapheresis– is useful in ABO blood group patients, in this procedure fresh frozen plasma is collected.
  • Erythrocytapheresis-Is the removal of erythrocytes from whole blood and is mainly done in sickle cell anaemia patients.
  • Plateletpheresis – It is a blood platelet in which a collection of the platelets is done by apheresis using various components.
  • Leukapheresis– removal of the basophils, or the patients who are ineffective for traditional therapy.
  • Stem cell harvesting– They are circulating bone cells into bone marrow transplants.

Indications

  • Guillain barre syndrome -is the rare disorder which attacks the nerves  of the immune system.
  • Myasthenia gravis(acute short term treatment) is characterised by weakness and fatigueness of the muscles.
  • Good posture syndrome – is an acute illness which affects the lungs and kidneys.
  • Chronic inflammatory demyelinating polyneuropathy- is the neurological disorder progressively weakness and sensory functions in arms and legs

Relation of Hemapheresis with Raktashodhana

Raktshodhana is the process where the detoxification is done by many various methods. It cleanses the body and removes the impurities out of it . These procedures are performed by the ayurveda doctors. It is the purification of blood which can be done by two methods

  • Local purification which can be done of the localised area of the hand legs which is not spreading.
  • Systemic purification- This is further explained in panchkarma. This is done by four methods :
  • Shrings (by the use of horns)
  • Jaloukavacharna (leech therapy)
  • Siravedan (multiple punctures)
  • Alabu (gourds)

A siravedann process is also done, that is venesection. In the systemic purification there is the whole body involved. Certain herbs are also provided such as tikta kashaya katu ras that are beneficial in blood purifications.

Raktamokshan

1. Jaloka Avacharan

This is ashastrakrita. Jaloka mainly live in cold places and are mainly found in water. There are 12 types of jaloka found, in which 6 are savish jaloka and 6 are nirvish jaloka. Mainly known as leech therapy. Leech therapy (hirudotherapy) – has 34 components. Leech has 32 brains and has an olive colured background. Leech is stored in non chlorinated water, and stored in a tight fit box, change of water is needed twice a week.

  • Chemical constituents of saliva of leech
    • Hirudin- It is an anticoagulant
    • Hyaluronidase-  Foster the flow of blood
  • Hirudotherapy Properties -act as bloodletting, anticoagulant, thrombolytic, immunostimulating.

2. Alabu

This process is done in kapha dushti. Alabu is ruksha, katu, tikshna gunayukt. Alabu has a length of 12 angula. In this bitter gourd is used for this procedure. The affected site is cleaned with all aseptic procedures and fire is extinguished at the affected site and one end of bitter gourd is opened and let drink of blood. After this the gourd is taken out and certain ayurveda thailam ghrita are used for healing.

3. Shringi

This process is done for vat dushti. Shringi is madhur, ushan, snigdha gunyukt. Shring is a cow horn for expelling blood out. In this fluid and pus are coming out of the orifice, on one side hand is kept and from other side blood is drawn out. This is hot in potency and is viable for letting blood out which is caused by vata dushti. But when the dushti is due to kapha dosha then the use of shrings are not used as thickness of blood is more.The horn used in this process should be conical shape.

4. Siravedan

Siravedan is a bloodletting procedure by puncturing. Not more than 768ml of blood should not be expelled out.Different types of instruments are used for blood letting such as kuthari instrument, vrihimukha instrument. Siravedan is mainly done in varsha kaal, grishm ritu, hemant ritu. Siravedan is contraindicated in extreme cold, and hot climates. In siravedan the physician should tap the vein and by holding a sharp instrument must puncture the vein without shaking the hand. After the procedure the site must be washed. Patients who undergo venesection must avoid heat, fear, prolonged sitting because this increases pitta dosha. Ideal siravedan brings lightness in the body.

Herbs Used As Raktashodhak

  1. Manjistha (Rubia cordifolia): It is a famous herb for blood detoxification. Manjistha has guru guna, rooksha (dry), tikta rasa ( bitter) madhura (sweet) and ushana (hot). It balances kapha and pitta. It cleanses the blood and boosts immunity. It provides clear skin.Manjistha is thick and long which has coloured bark.The flowers are small and green in colour. This herb is mainly found in many parts of the world which is called by many different names in every part. It has detoxifying properties, anti-inflammatory  and antimicrobial properties.
  2. Sariva (Hemidesmus indicus): has madhur ( sweet) and tikta (bitter) rasa, has guru guna ( heavy) and snigdha (oily) and is coolant. Sariva is widely used in treatment of anorexia, mennorrhagia.This herb undergoes sweet taste after digestion. Sariva is very helpful in low digestion strength and balances kapha and vata. The root part is used.
  3. Haridra (Curcuma longa): Haridra increases agni as it has ushna virya (hot)  katu tikta ras, haridra cleanses and detoxifies ras (digestive juice) Haridra enables the free moving of vata which is blocked by contaminated kapha and pitta. Haridra has antioxidant property which enable the free circulation of oxygen as many nutrients to the cells.
  4. Neem(Azadirachta indus): known as margosa tree. It has tikta (bitter) and kashaya ras (astringent) laghu guna (light) and katu vipaka.It balances vata dosha and removes ama, purifies the blood and it has antibacterial and antiviral properties. It is a natural detoxifier. It has cold potency, easily digestible and relieves excessive thirst and cures cough. Neem is very useful in healing wounds and in many skin diseases.It balances the pitta dosha, helps in diabetes.
  5. Guduchi-(Tinospora cordifolia): has kshaya(astringent) and tikta ras (bitter) ,has laghu guna (light) with ushna veerya (hot). Used in treatment of many diseases like fever, diabetes, urinary tract infection. It balances tridoshas (vata ,pitta, kapha). It rejuvenates the body and relieves aama digestion. It is hot in potency so it works well in a burning sensation. The main part used is the stem. Guduchi along with jaggery is used to relieve constipation, and is good in anaemic patients.

Conclusion

Hemaphersis is the therapeutic plasma exchange (TPE) which involves removing blood from the donor. It involves the direct blood into the donor veins through tubing to a machine which separates blood and its components. Hemapheresis is related to ayurveda by raktshodana and process of raktamokshana is done by jaloka, alabu, shring and siravedan,which helps in expelling of blood and its toxins from the body.Certain ayurveda herbs are also indicated in hemapheresis such as manjistha, neem, sariva,guduchi are explained as above. If you have any query you may contact us on www.PlanetAyurveda.com.