Category: Blood Disorders

Natural Remedies for Sideroblastic Anemia (blood disorder)

Abstract

In this article our main topic of discussion will be a very common blood disorder known as sideroblastic anemia. It is a type of anemia and has a great prevalence rate. Ayurveda deals with such ailment by doing detailed study of individuals prakriti (nature), and then we uses medication according to that by following basic principles of ayurveda tridosha theory (three principle energies of our body- vata, pitta and kapha) and panchamahabhuta theory (five basic elements of life- akash (sky), vayu (air), agni (fire), jal (water) and prithvi (mother earth). So let’s start discussing this in more detail.

Introduction

Sideroblastic anemia is a type of anemia in which bone marrow starts producing ringed sideroblasts (they are nucleated erythroblasts that are precursors to mature red blood cells) instead of normal red blood cells (erythrocytes). In a normal healthy person these sideroblasts are present in bone marrow and enter blood circulation after maturing into red blood cells. So this process of maturing and entering into the main blood stream of sideroblast got affected in sideroblastic anemia.

As per ayurveda we can correlate this with “pandu roga”. In this pitta dosha gets aggravated in the body due to those body tissues starting undergoing inflammatory reactions that make the body weak and lethargic. This leads to deterioration of varna (colour), bala (strength), sneha (protective fat layer of the body) and ojas (immunity power).

causes of sideroblastic anemia

Etiological Factors

These are the main causes (nidan as per ayurveda) that results in formation of an ailment.

In sideroblastic anemia the common causes are as follow

  • Hereditary involvement- in most of the cases congenital sideroblastic anemia occurs due to presence of x-linked sideroblastic anemia or autosomal recessive sideroblastic anemia.

Due to the presence of following genetic syndromes

  • Ataxia
  • Myopathy
  • Pancreatic insufficiency
  • Excessive alcohol consumption
  • Deficiency of vitamin B6 and copper
  • Lead poisoning.
  • Disorders of bone marrow.
  • Malnutrition

According to Ayurveda

1. Ahaaraj nidan (dietary causes)

  • Intake of amla (sour), lavan (salty), kshaar (alkali) and ushna (hot) food items.
  • Consumption of virudh and asatmya bhojan
  • Use of tikshna and vidagdha food substances.
  • Pramitashan

2. Vihaaraj nidan (lifestyle related causes)

  • Ati vyayam (over use of physical activities)
  • Divashayan (who sleeps during day time)
  • Ati maithun (excessive use of sexual activities)
  • Veg dharna (suppression of natural urges)

Prodromal Symptoms (Purvarupa)

These are the common complaints or early signs/symptoms that indicate onset of a disease.

Our acharya had clearly mentioned this in our ancient classical text and are as follows.

  • Palpitation
  • Dryness of skin
  •  No sweating
  • Fatigue
  • Excessive salivation
  • Malaise
  • Desire to eat clay/ mud
  • Swelling around the eyes
  • Yellowness of urine and stool
  • Indigestion.

Clinical Features

It includes the signs and symptoms. Asymptom means the general complaints along with patients present in front of the physician. Signs: It means what a physician notices himself by observing the patient’s condition.

  • Paleness in the skin.
  • Fatigue and malaise
  • Dizziness
  • Indigestion
  • Anorexia (loss of appetite)
  • Vertigo
  • Cramps in legs

According to Ayurveda

  • Pallor of skin
  • Scanty blood
  • Fat deficiency
  • Loss of glow
  • Tinnitus
  • Generalized body weakness
  • Anorexia (loss of appetite)
  • Fatigue
  • Vertigo
  • Fever
  • Exertional dyspnoea
  • Fall of hairs
  • Hate cold environment
  • Excessive sleep
  • Speech becomes feeble in nature.
  • Cramps in calf region

Types of sideroblastic anemia

1. Type 1 sideroblasts: Presence of less than 5 siderotic granules in the cytoplasm of the cell.

2. Type 2 sideroblasts: There will be a presence of 5 or more siderotic granules in this type.

3. Type 3/ ring sideroblasts: Presence of 5 or more granules in a perinuclear position that covers the one third portion of nuclear circumference. This type is included in sideroblastic anemia whereas the previous first two types are included in non sideroblastic anemia.

Complications

It means certain conditions that might occur in future due to presence of sideroblastic anemia for a long term basis.

  • Anorexia
  • Excessive thirst
  • Vomiting
  • Headache
  • Indigestion
  • Emaciation
  • Fainting
  • Malaise
  • Cardiac pain
  • Exertional dyspnoea
  • Diarrhea
  • Cough
  • Burning sensation
  • Hoarseness of voice

Diagnosis

Detailed physical examination of the patient by using inspection, palpation, percussion and auscultation techniques.

Laboratory findings: Complete blood count test

  • It shows a high level of serum iron and increased ferritin levels.
  • Decreased total iron binding capacity.
  • On blood smear- Presence of ringed shaped sideroblasts are seen.

According to Ayurveda – The two most preferred diagnostic procedures used by a physician are as follow

Trividh pariksha (Group of 3 diagnostic procedures)

  • DarshanDiagnosis is made by visual examination of the symptoms.
  • Sparshan-Physician uses tactile examination to evaluate whether skin is cold/hot
  • Prashan– Physicians ask direct questions from the patient, to evaluate the root cause of the disease i.e. history taking.

Asthavidh pariksha (set of 8 examination procedure)

  • Nadi pariksha– By palpating the pulse rate of the patient.
  • Mutra pariksha– By examining the urine of the patient.
  • Mal pariksha– By stool examination.
  • Jivha pariksha– By examining the tongue whether coated or not.
  • Shabad pariksha– By listening to the natural sounds within the body like intestinal sound (peristalsis) sounds of moving body fluids.
  • Sparsh pariksha– By observing the patient skin texture whether it is cool, wet or dry.
  • Drik pariksha– When a physician inspects patient symptoms through his/her eyes.
  • Akriti pariksha– When a physician evaluates the general appearance of a patient whether he/she looks dull, lethargic or fatigued etc.

Management

According to Ayurveda the main line of treatment is as follow

  1. Nidan parivarjan chikitsa (avoiding the root cause of disease) – This treatment modality had been given utmost importance in our ancient text. As according to ayurveda
  2. Sanshodhan chikitsa (detoxification procedure)-  As per charaka chikitsa 16/40-

We need to follow below listed therapeutic procedures

(i). Abhiyantra sanehan– Smoothing the internal dosha’s of our body by using herbally medicated ghrita/oil.

Example

  • Panchagavya ghrita
  • Mahatikta ghrita
  • Draksha ghrita

Dosage: 10-20 ml with warm water after meals.

(ii). Tikshan sanshodhan– In this tikshna herbs are used for vaman and virechna karma

  • Vaman (emesis) – emetic medicines are given to the patient to take out the vitiated dosha of the body.
  • Virechana (purgation) is the best technique to release out the pitta dosha from    the body by anal route. We can use- gomutra and haritaki churna for this.

(iii). Basti- In this liquid form of medicine is put inside the body via anal route with the help of specially made basti yantra (instrument). In sideroblastic anemia we will use rakta basti specifically.

3. Sanshaman chikitsa (Oral medications) – In this use of medication by oral route is done.

1. Rasa/bhasma/loha/mandur

  • Punarnava mandur
  • Navayas loha
  • Yograj
  • Loha bhasma

Dosage: 125-250 mg with honey or water after meals.

2. Vati

  • Arogyavardhini vati
  • Mandur vatak

Dosage: 250-500 mg with honey or water after meals.

3. Asava

  • Lohasava
  • Drakshasava

Dosage: 20-40 ml with equal amount of water after meals.

4. Avaleha

  • Dhatri avaleha
  • Drakshavaleha

Dosage: 10-20 gm with water after meal.

List of Planet Ayurveda Herbal Formulations

Herbal Remedies for Sideroblastic Anemia

Planet ayurveda has been serving people worldwide for the past 20 years with their holistic approach to healing. Their herbal products are made under the guidance of ayurveda experts and are very effective in maintaining a healthy and sound body as they are completely pure and organic in nature. They offer various herbal formulations that works really well in condition like sideroblastic anemia, some of them are as follow:

  1. Green Essentials
  2. Spirulina capsules
  3. Punarnava mandur
  4. HemoPlan syrup
  5. Suvarna Basant malti ras

Products Description

1. Green essentials

This herbal formulation contains potent blend of medicinal herbs such as

  • grape seed (Vitis vinifera)
  • wheat grass (Triticulum aestivum)
  • spirulina (Spirulina platensis)
  • green tea (Camellia sinensis)
  • amla (Embllica officinalis)

All the herbs present in this herbal formulation have great immunity enhancing properties. It also contains a good amount of antioxidants and other necessary nutrients that will assist very profoundly in sideroblastic anemia.

Dosage: 1 capsule twice daily with plain water after meals.

2. Spirulina capsules

This capsule contains a pure form of spirulina (Spirulina platensis). It is a rich source of various healthy micro and macro nutrients. It is known for its immunity enhancing property. It also has anti cancerous properties so helps in maintaining overall strength and stamina of patients of sideroblastic anemia.

Dosage: 1 cap twice daily with plain water after meal.

3. Punarnava mandur

This herbal formulation is imbued with plenty of therapeutic actions as it contains punarnava (Boerhaavia diffusa) which is very effective in increasing the digestive power of the body. Other herbs present in the formulations such as

  • pipali (Piper longum)
  • sunthi (Zingiber officinale)
  • amalaki (Emblica officinale)
  • haridra (Curcuma longa) etc

Contain anti-inflammatory antifungal properties so it works really well in patients suffering from sideroblastic anemia.

Dosage: 2 tabs twice daily with plain water after meal.

4. Hemoplan syp

This herbal syrup is potent blend of various medicinal herbs such as

  • manjishtha (Rubia cordifolia)
  • shatavari (Asparagus racemosus)
  • gorakhmundi (Sphaeranthus indicus)
  • ashwagandha (Withania somnifera)
  • draksha (Vitis vinifera)
  • sariva (Hemidesmus indicus).

It has great blood enhancing properties that will help in increasing hemoglobin concentration in the blood. It also helps in providing strength and stamina to patients suffering from sideroblastic anemia.

Dosage: 2 tsf twice daily after meal.

5. Suvarna Basant malti ras

This herbomineral formulation contains properties like anti-inflammatory (reduce inflammation). It helps in boosting up the immunity of our body by balancing tridosha. It also possesses “rasayan” property that rejuvenates the body channels and helps in lengthening the lifespan of sideroblastic anemia patients. It contains marich (Piper nigrum), kharpara bhasma (calamine in an incinerated form), shuddha hingula (cinnabar in a purified form), swarna bhasma (gold in an incinerated form) etc.

Dosage: 1 tab twice daily with plain water after meal.

Contact my assistant to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214030 Or Check Website – www.PlanetAyurveda.com

Conclusion

We can now conclude that in an ailment like sideroblastic anemia ayurvedic herbs works very efficiently. In sideroblastic anemia the main culprit is the elevated Pitta dosha so our main concern is to deal with it intrinsically. For Ayurvedic treatment, you can consider choosing Planet Ayurveda as we have been serving mankind with our holistic approach of healing. You can directly visit us at our clinic at Mohali, Punjab or can send your queries on our official email id- herbalremedies123@yahoo.com

Herbal Remedies for Glanzmann’s Thrombasthenia – Bleeding Disorder

Abstract

Glanzmann’s thrombasthenia (GT) is an inherited blood clotting disorder which is characterized  by impaired function of specialized cells called as platelets that are essential for blood clotting (coagulation). The symptoms generally include abnormal bleeding and if left untreated for a long time can prove fatal. GT can be managed in a safe and effective manner with the help of Ayurvedic mode of treatment. In this article, lets’ know about this disease in brief and discuss Ayurvedic herbal remedies for the disease.

Introduction

Glanzmann’s thrombasthenia is a bleeding disorder which is characterized by spontaneous bleeding starting from birth. In Glanzmann’s Thrombasthenia a person tends to bleed easily, may also present with easy skin bruising, can have frequent nosebleeds (epistaxis) and bleeding gums. Such patients can present with purple or red spots on skin which are usually due to bleeding underneath skin or swelling caused by bleeding within tissues. People with this disorder tend to bleed a lot following injury or surgery. Females with Glanzmann’s Thrombasthenia have excessive bleeding during menses and bleed more than usual after child birth. This excessive bleeding can result in extreme blood loss and can be fatal.

Symptoms of Glanzmann's Thrombasthenia

Causes of Glanzmann’s Thrombasthenia

This condition is a result of gene mutation. The Mutation in ITGA2B or ITGB3  results in  this condition. This gene is responsible for making two parts (subunits) of receptor protein integrin alphallb/beta3. This protein is abundant on the surface of platelets. Platelets are the small cells which circulate in blood and are an important component for clot formation. During coagulation integrin helps the platelet to combine together. The clot formation protects the body after injury by sealing off the damaged blood vessels and hence bleeding stops.

The gene mutation results in the deficiency of integrin alphallb/beta3. Due to its deficiency the platelets cannot clump together thus resulting in prolonged bleeding.

In some cases of Glanzmann’s Thrombasthenia no mutation is seen in integrin alphallb/beta3. In such cases the cause for the condition is not known.

Types of Glanzmann’s Thrombasthenia

Type 1:  In this type people have less than 5 percent of integrin alphallb/beta3 levels. This is the most common type.

Type 2: In this type people have 5-20 percent of integrin alphallb/beta3 levels.

Variant type: In this type the body produces an adequate amount of integrin alphallb/beta3 but it is nonfunctional.

Symptoms of Glanzmann’s Thrombasthenia

The symptoms in this case include

  • Tendency to bleed starts right after birth or short time.
  • Purple or red spots on skin
  • Bleeding gums
  • Bleeding nose (epistaxis)
  • Excessive bleeding during surgery or after surgery.
  • Intermittent gastrointestinal bleeding resulting in melena
  • In women excessive menstrual bleeding
  • Excessive bleeding during childbirth and after childbirth
  • Intermittent uterine bleeding
  • Blood in urine
  • In severe conditions hemorrhage and this can be fatal.

Treatment of Glanzmann’s Thrombasthenia

In modern science there is no specific treatment for this condition. The treatment   includes preventive measures like protecting oneself from injuries in case to avoid blood loss, some antifibrinolytics drugs to stop excessive bleeding, blood transfusion, if required.

Planet Ayurveda is a herbal based drug manufacturer that makes products in strict adherence to the Ayurvedic texts. The various drugs that are being manufactured here are well collected from natural sources, then purified & then formulated into different preparations. These products are made under the supervision & vigilance of our expert Ayurvedic doctors by ancient time tested formulas.

Herbal Remedies for Glanzmann’s Thrombasthenia

Ayurvedic Medicines for Glanzmann’s  thrombasthenia

Planet Ayurveda offers following herbal drugs for the management of this disease

  1. Immune booster
  2. Giloy Ghan Vati
  3. Kumar Kalyan ras
  4. Green essentials
  5. Punarnava mandoor
  6. Spirulina capsules

Product Description

1. Immune booster

The immune booster capsules are made up by combining different herbs like bhumi amla (Phyllanthus niruri), amalaki (Emblica officinalis) etc. In production of these capsules standardized extract of bhumi amla, amalaki and other drugs are used. Bhumi amla is a blood purifier and also works on skin conditions. In GT it will work by purifying blood and reducing skin spots.  On the other hand, amalaki is the highest source of heat stable vitamin C which is excellent for boosting metabolism.

Dosage: Two capsules twice a day.

2. Giloy Ghan Vati

This vati uses standardized stem extract from Tinospora cordifolia plant. Medicinal effects of the plant are blood purification, antipyretic properties, anti-inflammatory effects as well as work on immune system enhancement. In GT it can help to reduce tissue swelling due to bleeding within tissues hence reducing skin spots.

Dosage: Two tablets daily.

3. Kumar Kalyan ras

The Kumar Kalyan ras is available in chewable tablet form especially for children with glanzmann’s thrombasthenia. This tablet has antipyretic properties, also used in persistent cough conditions, boosts metabolism and many more.

Dosage: one tablet twice daily (to be chewed) with honey.

4. Green essentials

This is a kind of Ayurvedic multivitamin capsules and can be used in GT as to avoid any kind of deficiency. The product contains wheatgrass which is a great source of iron, calcium, magnesium, amino acids etc. It also contains spirulina which is having a great antioxidant, anti-inflammatory and anti-allergic properties. Other ingredients are amla which is a great source of vitamin C, grape seed and green tea.

Dosage: one capsule twice daily.

5. Punarnava Mandoor

Punarnava mandoor has many ingredients like punarnava (Boerhaavia diffusa), mandoor (purified ore of iron), amalaki (Emblica officinalis), haridra (curcumin) etc. Punarnava in this formulation have anti spasmodic, anti-microbial and anti-inflammatory properties, mandoor is well known for its hematogenic and haematinic effects. This can be used in patients of GT to avoid deficiency of blood and other important minerals.

Dosage: Two tablets twice daily.

6. Spirulina Capsules

These capsules contain spirulina which is having great antioxidant, anti-inflammatory anti-allergic properties. Spirulina is also used in treating anemia. In GT this will help in maintaining normal blood levels in the body.

Dosage: 2 capsules twice daily.

Contact my assistant to provide you the costing/ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214030 Or Check Website – www.PlanetAyurveda.com

Conclusion

The products which are offered by Planet Ayurveda for the Treatment of Glanzmann’s Thrombasthenia are totally herbal which are and obtained from natural resources, so they help in treating the cause of the disease & side by side promoting immunity. These drugs also have lesser side effects as compared to the drugs/methods used by Modern medicine. However, it is advised that people suffering from Glanzmann’s Thrombasthenia should use these herbal products under the guidance of an expert Ayurveda practitioner.