hepatic inflammation Archives | Dr. Vikram Chauhan's Blog

Treatment of Crigler Najjar Syndrome Type 1 in Ayurveda

If your child has been suffering from constant episodes of jaundice, it’s time to unravel the underlying cause.

Here’s Ayurveda for your empowerment!

Jaundice is most often misunderstood maturity of the world, it’s true it can occur as a result of disrupted habits of an individual but repeated episodes of this malady are no joke!. The term syndrome stands for a group of signs portrayed in the individual during a pathology. Crigler Najjar syndrome is a genetic condition where the liver loses its ability to break down bilirubin in the blood resulting in repeated episodes of jaundice in many individuals. Does it sound crazy? Let’s simplify it then!

A better Understanding

The liver is the site for all metabolic transformations of the body and this is the same site where the blood contents are destroyed. The blood hemoglobin is separated into iron and protein entities of which protein is further divided into bilirubin and biliverdin. The bilirubin is pushed into the alimentary canal and colors the stool. So when the bilirubin is not properly synthesized or its transportation is hampered it travels to all other areas of the body except the alimentary canal and causes color discoloration in skin mucosa causing jaundice. In Crigler Najjar syndrome, the child is born with a gene defect where a proper breakdown is not initialized, also those who have persistent jaundice soon after birth are susceptible to this disease manifestation.

Here are the Signs and treatment

According to modern scientists, the condition is believed to manifest with genetic background. For this reason, the symptoms mostly experienced by the individual will be repeated jaundice-like presentations without any other associated complaints. Gene mutation is understood as the cause as well. Diagnosis for this condition is formed with a blood sample containing traces of bilirubin glucobilinoids in bile. Often a liver biopsy may also be suggested by your doctor.

Being a purely genetic manifestation, The treatment for this condition is achieved through symptomatic relief and dietary supplements that support liver function. For this oral or parenteral supply of heme oxidase inhibitors are supplied to reduce the load of bilirubin in blood. With ample treatment methodologies in the market, the disease has a fairly good prognosis pattern, provided the condition does not deepen into kernicterus.

Crigler Najjar Syndrome Type 1

AYURVEDA’S ACTION IN THIS SYNDROME

Ayurveda, an age-old science of life, understands and comprehends a disease through the perspective of Doshas, the bodily entities that govern all the metabolic and mechanical functioning of the body. With our modern view on the functioning of the body, the treatment methodology of this branch of science might seem to be peculiar surely but it is effective.

Ayurvedic Pathophysiology

Here all disease formations are propelled into drastic seniors in the presence of an impaired digestive fire or Agni. In the Ayurvedic system of medicine, Yakrit or liver is the reservoir of blood tissue elements and also the site of localisation of the Pitta entity. With digestion and liver metabolism at stake, the pitta entity loses its control in the general metabolism and tends to flow freely with the vata entity resulting in discoloration throughout the body as jaundice. All immune-compromise maladies occur in the body due to compromised Ojas or coefficient of immunity, so is the condition here.

Thus the treatment protocol used in this field begins with medications that are digestive and carminatives that normalizes the pitta within the digestive fire. Later the pitta entity within circulation is brought back to the liver where it is metabolized using the rightful utility of specific detox therapies according to the condition of the patient. Further,the immune status of the body is normalized using rejuvenations that ensure fullon metabolic enhancement at all spheres of health.

PLANET AYURVEDA FOR YOUR SUPPORT

Here on planet Ayurveda we use the best herbal drugs right from nature’s basket to aid your wellbeing. We have thus introduced our liver care pack formulated to normalize the hepatic mechanisms of your body.

Herbal Supplements for Najjar Syndrome Type 1

1. Yakritplihantak Churna

This authentic formulation is composed of herbs that improve the general metabolism of the silver and ensure prudent liver cell regeneration during the normalcy of the organ. It is advised to consume this by preparing a decoction of 1 teaspoonful of the powder in 400 ml of water and reducing it into 50ml. Once cool you can strain and consume it twice daily or as recommended by your ayurvedic physician for better results.

Dosage– 1 tsp twice daily with lukewarm water

2. Phyllanthus Niruri

Ayurveda infers the importance for certain herbs with exceptional qualities against a maldity, these are called Arge Aushada. One such Agre Aushadam for liver dysfunctions is BhumyAmalaki (Phyllanthus amarus). It contains many hepatoprotective phytoconstituents that ensures the optimacy for liver mechanism. Its hot potency which normalizes the digestive fire while its astringent flavour has the same metabolic end effect that normalizes the pitta entity as well.

Dosage-It is advised to consume 2 capsules twice daily after meals or as recommended by your ayurvedic health professional.

3. Echinacea capsules

The kalamegha or Andrographis paniculata is known as the king of bitters. It is a wonderful immune stimulant with wonderful restorative ability. It has the potential to normalize all systemic mechanisms of the body including liver metabolism.

Dosage-It is advised to consume 2 capsules twice daily after meals or as directed by your ayurvedic health care practitioner.

4. Liver Detox Capsules

If your liver is healthy, then your system is healthy. This mystic combination of herbs like Klamegha (Andrographis paniculata) and many others helps to normalize the functionality of the liver. It helps clean the liver and offers ample space for liver detox and rejuvenation.

Dosage-It is advised to consume 2 capsules twice daily after meals or as instructed by your ayurvedic physician.

While taking dietary supplements that support our well-being, Ayurveda strictly ensures that right dietary adaptations and lifestyle modifications must be incorporated to sustain our health. While this Indian science does not show results overnight, through adamant determination you are sure to reach your goals.

By imbibing in the goodness of this holistic science you are sure to restore your metabolic wellness and spiritual upliftment.

Contact my assistant to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214040 Or Check Website – www.PlanetAyurveda.com

Choose Ayurveda to reward yourself well-being!

Yakrit Plihantak Churna Regulates TNF-Alpha & IL1-beta and Reduces Hepatic Inflammation

Overview

As the Ayurveda system of medicines is the oldest and natural medicinal system, a large number of chronic diseases can be treated with Ayurvedic medicines. Ayurvedic medicines are made up of natural herbs only which treat the root cause of the disease in a natural way without showing any side effects. From one of the dreadful disorders, hepatic inflammation is one and affecting a large portion of the population. But to treat this, Yakrit Plihantak churna is used and very positive results of this herbal remedy are observed. In this article, we will study about the disorder hepatic inflammation and how Yakrit Plihantak churna provides relief from this condition.

What Is Hepatic Inflammation?

Hepatic or Liver inflammation can be defined as the reaction occurring after attack by a disease-causing substance or microbes on liver cells. It affects the various digestive functions along with some other activities occurring in the liver and makes the patient uncomfortable due to inflammation. Major functions performed by the liver includes production of bile for converting food into energy, production of hormones, regulating fat storage, cholesterol generation, purifying the blood and excreting toxins from the body including alcohol and drugs. But due to hepatic inflammation, all these activities got disturbed.

The term “Hepatitis” is considered for inflammation of the liver. Most types of hepatitis occur from viral infection and sometimes by auto-immune disorders hat affect the body’s immune system which further begins to attack liver cells and cause inflammation in the liver.

hepatic inflammation

Signs and symptoms observed in the patient of Hepatic inflammation include

Yellowness of the eyes and skin
Intermittent vomiting
Nausea
Pale stool color
Dark urine color
Itchy skin
Swelling in the ankles and legs
Pain and swelling in the abdominal area

What Is Tnf-Alpha?

TNF-alpha stands for Tumor necrosis factor-alpha. It is a cytokine or we can describe it as a small protein brought in use by the body’s immune system for passing signals through the cells. When an infection is detected by the macrophages (certain white blood cells), secretion of TNF is done to alert various other cells of the immune system and various tissues from being infected. This mechanism results in inflammation in the whole body.

When an infection or disease starts to develop in the liver cells, inflammation in the liver is done by TNF-alpha. This inflammation makes the patient troublesome in doing daily routine activities. TNF-alpha is a necessary body compound which protects the other body organs by alerting them but its way of working is found to be annoying to the body. Meanwhile, we can say that inflammation is considered as the good sign of the health of the immune system and shows that the body’s immune system is working wisely.

What Is Il 1-Beta?

IL 1-beta implies Interleukin 1-beta, also recognized as lymphocyte activating factor, mononuclear cell factor, leukocyte endogenous mediator or leukocytic pyrogen. Basically it is a cytokine protein which is encoded by IL1B gene in the human body. IL 1-beta is a part of the interleukin 1 family of cytokines. This cytokine is secreted by stimulated macrophages as a proprotein which further gets converted into an active state by caspase 1 (CASP1/ICE). This cytokine is considered as an essential mediator of the inflammatory response and plays an important role in multiple cellular functions such as cell proliferation, apoptosis and differentiation. This cytokine does the enhancement of COX-2 (cyclooxygenase-2) enzyme in the CNS (central nervous system) which contributes to inflammatory pain. When the infection begins to rise inside the liver cells, the IL 1-beta begins to protect cells and results in inflammation.

Yakrit Plihantak Churna By Planet Ayurveda

Yakrit Plihantak churna prepared by Planet Ayurveda is a well known herbal formulation for its positive impact on the liver and enhance its health. This churna reduces hepatic inflammation as well as treats a variety of diseases associated with the liver. Yakrit Plihantak churna detoxifies the liver and restores its health. Along with that, hepatic inflammation is managed and reduced by this churna which provides the relief to the patient.

This churna is processed with eight herbs obtained from the nature of God. Thus, we can say that one churna consists of the potency of eight herbs. All these herbs are used by extracting them through a standard procedure and only high quality extracts are used in preparing this churna under the guidance of expert Ayurvedic doctors who ensure this churna is 100 percent natural. No preservative, chemical, color, additive, binder, starch or any chemical material is utilized in this churna. Thus, no side-effect will be given to the patient who is consuming Yakrit Plihantak churna, whether he is a child, an adult or an elder. This churna is totally safe for consumption by any age grouped person.

Yakrit Plihantak Churna

Herbs present in Yakrit Plihantak churna work in a synergistic manner to reduce inflammation in the liver.

These Herbs are

Bhumi Amla (Phyllanthus niruri)
Katuki (Picrorhiza kurroa)
Makoy (Solanum indicum)
Punarnava (Boerhavia diffusa)
Kalmegh (Andrographis paniculata)
Kaasni (Cichorium intybus)
Sharpunkha (Tephrosia purpurea)
Bhringraj (Eclipta alba)

How Yakrit Plihantak Churna Reduces Hepatic Inflammation?

Yakrit plihantak churna is very beneficial in reducing hepatic inflammation due its properties possessed by various herbs present inside the churna. All these herbs are rich sources of various health beneficial properties that provide nourishment to the liver and treat the multiple diseases of the liver. The role of herbs in maintaining the health and reducing hepatic inflammation is as follows:

1. Bhumi Amla (Phyllanthus niruri)

Multiple medicinal properties are present in Bhumi Amla herb which makes it capable of managing various health issues. Hepatoprotective properties, antioxidant properties, antiviral properties, etc are present in this herb. It regulates the functioning of Tnf-alpha and IF-1 beta. Hence reduce the hepatic inflammation.

2. Katuki (Picrorhiza kurroa)

Active constituents present in the roots of Katuki are picrorrhizin (a bitter ingredient) 15 %, cathartic acid 9%, glucose and wax in small quantities. These chemical constituents improve the bilous flow and prevent the deposition of fat and bile inside the liver cells. It reduces the risk of liver disease and maintains its normal functioning.

3. Makoy (Solanum indicum)

Makoy herb used in the Yakrit Plihantak churna consists of diosgenin, epicatechin, solasonine, alpha, glycosides, rutin, naringenin, gallic acid, sapogenin, etc. These chemical constituents provide the property of antidiabetic, antibiotic, antiseptic, anti-inflammatory, diaphoretic, etc. Hepatic inflammation is reduced to a great extent by this herb.

4. Punarnava (Boerhavia diffusa)

Punarnava is a rich source of nutrients and bioactive substances which are beneficial for the overall health. Sodium, calcium, vitamin c, iron, oleanolic acid, hypoxanthine, boeravinone A to F, serratagenic acid, etc are found in this herb. Punarnava improves the body metabolism and improves the functioning of the liver.

5. Kalmegh (Andrographis paniculata)

The whole part of the Kalmegh herb contains chlorophyll and kalameghin in large quantities which is used to treat diseases developed through imbalance in Pitta and Kapha dosha. This herb is used as liver stimulant, digestion enhancer and in prevention of liver and spleen enlargement. Beyond this, Kalmegh improves blood metabolism, treats jaundice, constipation, diarrhea and enhances liver health. TNF alpha and IL 1-beta are successfully managed by this herb and hepatic inflammation is prevented.

6. Kaasni (Cichorium intybus)

Being a cholagogue, appetizer, and liver stimulant, Kaasni treats the health issues generated by impaired agni, liver dysfunctions, and jaundice. This herb is also used in general debility, pitta induced disorders, burning sensation and fever.

7. Sharpunkha (Tephrosia purpurea)

Sharpunkha herb’s nature is to optimise the secretion of bile and prevents the accumulation of fat as well as bile inside the liver cells which is the major cause of liver disease. The healthy condition of the liver is maintained by this herb due to its anti-toxic, diuretic and antipyretic properties.

8. Bhringraj (Eclipta alba)

Large quantities of resins and ecliptin are present in this herb. That is why it is processed in the Yakrit Plihantak churna. It is a strong liver stimulant, and shows its main action on the liver and the spleen. It provides protection to the liver and stimulates lipotropic activity which increases the cutdown of the fat and prevents its deposition in the liver. Thus, decrease the hepatic inflammation.

Conclusion

After reading and understanding this article, we can say that Yakrit Plihantak churna is an effective herbal remedy to overcome the disorders of liver and improve the life-span of the liver. This churna is totally natural and doesn’t possess any side-effects of the patient’s body.