Sting-associated vasculopathy is an uncommon disorder that causes aberrant inflammation and skin and interstitial lung disease lesions. It was originally found in 2014. Because of the gene mutation that results in it, it is a hereditary condition. High death rates are associated with its characteristic neonatal onset. Now, we discuss sting-associated vasculopathy in detail. The affected person experiences the Raynaud phenomenon, in which the affected area turns red with exposure to cold and stress and changes color from white to blue. It might also be required for amputation.
The hereditary disorder known as “sting-associated vasculopathy” causes aberrant inflammation throughout the body, with the skin, blood vessels, and lungs experiencing the most of the effects. It is an auto-inflammatory illness and a rare condition. It begins during infancy. Vasculopathy and interstitial lung disease are its primary characteristics.
Causes of SAVI
Genetic changes are the root cause of sting-associated vasculopathy. A mutation in the STING1 gene results in an overproduction of the inflammatory proteins that harm tissue and increase inflammation. This gene is important for producing the STING protein, which produces cytokines that cause inflammation.
Symptoms Of SAVI
- Unhealing wound
- Minimal fever
- Joint rigidity
- Muscle soreness
- Respiratory lesions
- Enlarged lymph node
- Failing to flourish
- Lungs with interstitial disease
- Skin blemishes can be found on the cheeks, nose, ears, fingers, and soles of the feet.
- A fibrotic lung
Diagnosis Of SAVI
- Chest X-rays
- Magnetic resonance imaging
- Blood culture
- Lung biopsy
- CT scan
- Genetic testing
This illness has no specific treatment. Management can only be supportive.
- Biological agents
Ayurvedic Aspect of Sting Associated Vasculopathy
In Ayurveda, we can correlate the sting-associated vasculopathy with onset in infancy with Bija dushti (Abnormal ovum and sperm).
According to Acharya Charaka: (च. शा. ३/१७)
This theory holds true for each and every srota (channel). Any Beeja Bhaga gene whose function is compromised by the doshas (Vata, Pitta, and Kapha) manifests as a sickness or disease. It falls under the heading of a hereditary disease called Sahaja or Kulaj roga. Genes, or bija bhaga avayava, are the fundamental building blocks of all living things. Genes contain the instructions needed to create, maintain, and pass genetic features to progeny in an organism. If the male and female are both bija damaged totally, neither can generate new offspring, but if just one is contaminated, the offspring will be defective. The bija bhaga avayava is where abnormal doshas (Vata, Pitta, and Kapha) enter, causing disease to develop there with symptoms like dyspnea, growth retardation, skin lesions, joint stiffness, and pulmonary diseases.
Genetic or hereditary illnesses cannot be cured. There is no known cure for this illness. Only supportive care can be provided to control symptoms and halt the spread of the disease. The following list of herbal treatments for SAVI is provided by Planet Ayurveda as supportive management.
Some Herbal Remedies for Sting Associated Vasculopathy by Planet Ayurveda
Planet Ayurveda is a certified ayurvedic clinic, and the formulation of different types of remedies is performed here to provide relief from diseases. All formulations at Planet Ayurveda are made organically without the use of preservatives. These remedies are formulated under the guidance of MD Ayurvedic practitioners. Planet Ayurveda offers a variety of herbal products that have no negative effects for treating sting associated vasculopathy.
- BOSWELLIA CURCUMIN
- INFEE SYRUP
- MANJISHTHA CAPSULE
1. Boswellia Curcumin
Boswellia curcumin is a multi-herbal capsule that includes haridra (Curcuma longa) and shallaki (Boswellia serrata). It has a spicy and bitter flavour. It harmonizes the body’s three doshas—Pitta, Kapha, and Vata. It is unctuous, dry, sticky, sharp, and light. It includes mineral stuff such as calcium, silicon dioxide, iron, volatile oil, and magnesium, as well as organic molecules and inorganic ions. For a variety of joint issues, including osteoarthritis, gout, and rheumatoid arthritis, it is a very helpful medication. It aids in lowering joint inflammation-related discomfort, soreness, and swelling.
Dosage: with plain water, after meals, take 1 capsule twice daily.
Arvindasav is a multi-herbal formulation that is formulated by Planet Ayurveda by using herbs like arjun (Terminalia arjuna), khairati (Sida cordifolia), mulethi (Glycyrrhiza glabra), manjith (Rubia cordifolia), and some other herbs. It has an unctuous, rich, heavy, and cold effect. All three doshas—Vata, Pitta, and Kapha—are calmed by it. It is a drug that acts as an antipyretic, anti-inflammatory, and wound healer. It enhances the complexion, soothes eye issues, acts as an antacid, and is also a potent general tonic. Calcium, glucose, starch, vitamin B, and potassium are all present in it. It liquifies the mucus and helps in its smooth excitation. It is indicated for cough, asthma, bronchitis, and other chest conditions. It enhances voice quality, supports body weight, and counteracts excessive thirst and weariness. It stimulates the digestive system.
Dosage: after meals, with equal amounts of water (10 ml twice daily).
3. Infee Syrup
Infee is a multi-herbal syrup that is formulated with the help of yashtimadhu (Glycyrrhiza glabra) and guduchi (Tinospora cordifolia). It balances the kapha, pitta, and vata-vitiated doshas. Additionally, it has antipyretic, anti-inflammatory, and wound-healing properties. It is unctuous, spicy, astringent and bitter. Fatty acids, alkaloids, volatile oils, and glycosides are all present. It is prescribed for conditions like gout, rheumatoid arthritis, fever, dyspepsia, and urinary disorders. It contains rejuvenating, immunomodulating, and antioxidant effects. It helps reduce the level of uric acid.
Dosage: 5 drops in infants and 1/2 tsp with water.
4. Manjishtha Capsules
Manjistha capsules are a single herbal formulation that is formulated by Planet Ayurveda with the help of Manjistha (Rubia cordifolia). It is a blood purifier, detoxifier, hematopoietic system booster, and complexion enhancer. Additionally, it functions as an antibacterial, hemostatic, digestive, and carminative agent. It has uterine stimulant and anti-inflammatory effects. It has a hot, dry, and heavy effect while tasting bitter, astringent, and sweet. It calms down the kapha and pitta doshas. It is advised in cases of dysentery, persistent fever, diarrhea, and uterine and urinary infections. It helps with scars, acne and blemishes and also repairs the skin tissues that have been harmed or infected.
Dosage: after meals, with plain water, 1 capsule twice daily.
Contact Planet Ayurveda Support Team to provide you the costing / ordering and delivery information at – email@example.com or Call at 0172-521-4040 (India), +91-172-521-4040 (Outside India) or Whatsapp at (+91) 9915-593-604
Sting-associated vasculopathy is an uncommon disorder that causes aberrant inflammation and skin and interstitial lung disease lesions. It was originally found in 2014. Because of the gene mutation that results in it, it is a hereditary condition. It is an auto-inflammatory illness and a rare condition. It begins during infancy. Vasculopathy and interstitial lung disease are its primary characteristics. In Ayurveda, we can correlate the sting-associated vasculopathy with onset in infancy with Bija dushti (Abnormal ovum and sperm). On Planet Ayurveda, there are some herbal formulations that are used for the management of sting-associated vasculopathy without causing any side effects.