Category: Periodic paralysis

Ayurvedic Management of Hypokalemic periodic paralysis (HypoKPP)

Abstract

All of you might be aware of Paralysis , which has become very common nowadays. It is the loss of muscular functions in any part of your body which may occur  due to stroke ,spinal injury, etc. But have  you ever heard about incidence of a recurrent paralysis caused by imbalance of mineral content of your body? Lets know more about one such condition.

HYPOKALEMIC PERIODIC PARALYSIS

Hypokalemic periodic paralysis (HypoKPP) is a disorder which causes episodes of severe muscle weakness usually commencing in early childhood. It is a rare autosomal dominant channelopathy attributed to weakness of muscle or paralysis when there is a decrease in potassium levels in the blood (less than 3.5.mmol/l). It affects about 1 in 100,000 people  and is more common in men. It is commonly a genetic disorder in which at least one parent is affected. There is a 50-percentage chance for an affected individual to have an affected offspring. Acquired cases of HypoKPP are also recognized which are related to hyperthyroidism.

HYPOKALEMIC PERIODIC PARALYSIS

CAUSES

Channelopathies are ailments caused by the dysfunction of ion channels.Ion channels are proteins that allow ions to pass through and involve functions such as maintaining a resting membrane potential, shaping action potentials and other electrical signals, thus acting on movements of the body.

Causes of HypoKPP are understood as following

  • Mutations in the CACNA1S or SCN4A gene :It reforms the usual anatomy and physiology of calcium or sodium channels, making the ions flow slowly but constantly into muscle cells, which reduces the muscle contraction. This results in episodes of severe muscle weakness or paralysis.
  • Acquired HypoKPP has been linked with thyrotoxicosis.
  • Periodic muscle weakness can also result from hypokalemia secondary to renal or gastrointestinal potassium loss in diseases like renal tubular acidosis, gastroenteritis, or other endocrine causes.

CLINICAL FEATURES

Symptoms of Familial HypoKPP have generally been exhibited since childhood. The frequency of attacks seems to decline with age. In the case of thyrotoxic HypoKPP, the onset is commonly after age 20.

  • Premonitory signs like exhaustion, paresthesia, behavioral differences.
  • Attacks of generalized muscle weakness, with proximal muscle involvement more significant than distal muscles. It causes severe weakness or paralysis that usually lasts from hours to days. Few people may have episodes almost every day, while others encounter them weekly, monthly, or just rarely
  • Muscle cramps, discomfort
  • In serious cases it may direct to cardiac arrhythmia or respiratory muscle paralysis which can be deadly
  • Attacks can be provoked by factors such as rest after a workout, a viral infection, or certain medications. Occasionally, a heavy, carbohydrate-rich meal or vigorous exercise in the evening can trigger an attack upon waking the next morning. Even though affected individuals usually retrieve their muscle strength between attacks, some emerge with persistent muscle weakness throughout their life.

INVESTIGATIONS AND DIAGNOSIS

  • Positive family history
  • Sudden onset of flaccid muscle weakness especially  proximal muscles with decreased deep tendon reflexes and drop in serum potassium level
  • Genetic testing  to identify gene mutation
  • Electromyography :During attacks of weakness, EMG shows decreased amplitude of compound muscle action potential (CAMP)
  • Exercise test:a strenuous exercise of a single muscle for 2-5 minutes is done to initiate focal muscle weakness and the change in post exercise CAMP in muscle fibers is measured by the EMG

MANAGEMENT

The major aim of treatment is to cure the symptoms of acute attacks, prevention and management of complications, and prevent future attacks. Judicious intake of oral  potassium chloride to maintain serum potassium levels,lifestyle modifications and preventing triggering factors can be done.

AYURVEDIC MANAGEMENT

Ayurveda is the ancient system of healing. It has a holistic approach to the wellness of individuals. It is based mainly on three doshas, the three humors which make up a human body. Ayurveda aims to bring equilibrium between these doshas and dhatus(body tissues). Hypokalemic periodic paralysis can be definitely treated with this holistic approach. This can be correlated with Pakshaghata Treatment. Vata dosha and mamsa dhatu(muscle tissues)are involved in this disease’s pathogenesis.  Ayurvedic therapy aims at bringing their level to normalcy.

PLANET AYURVEDA-THE SYMBOL OF PURITY

Planet Ayurveda is a leading venture in the ayurvedic pharmaceutical industry, well known for its credibility and purity. Our products are natural and free from adverse effects. We blend the 5000-year-old ancient knowledge of Ayurveda with modern systematic and scientific approaches. Our aim is the well being of every individual by natural healing. We have a wide range of herbal remedies made from a myriad of drugs which give noteworthy benefits.

Here are some herbal remedies for Hypokalemic periodic paralysis from planet Ayurveda

1. ASHWAGANDHA GHAN VATI

Enriched with the goodness of Ashwagandha (Withania somnifera), this is a single herb tablet preparation. Ashwagandha is a magical herb with immunoprotective, neuroprotective, and rejuvenating effects. Endowed with active components like withanolides, withaferin, etc., it improves the strength of body muscles. Several studies have also revealed that ashwagandha is rich in potassium. These factors substantiate its use in HypoKPP.

Dose:2 tablets twice a day with warm water is advised.

2. MUSLI STRENGTH CAPSULES

This is a polyherbal formula available in the form of capsules. Made up of two magnificent drugs Safed musli(chlorophytum borivilianum) and gokshura(Tribulus terrestris). Musli helps in enhancing the general fitness of the body and rejuvenates body tissues. Gokshura is abundant in saponins like Protodioscin which helps in muscle strengthening.

Dosage: 1 capsule twice daily with lukewarm water is advocated

3. GANDHAK RASAYAN

It is a sulfur-based preparation available in the form of tablets.It is a versatile drug having results on a wide range of ailments. It influences numerous metabolic processes in the body. It provides you with drudadeha (strong body) and is indicated in dhatu kshaya roga-diseases due to depleted body tissues like muscles in the Ayurvedic classics.

Dosage: it is suggested to take 2 tablets twice or thrice daily with lukewarm water.

4. GREEN ESSENTIALS

This is a fabulous polyherbal preparation attainable in the form of capsules. It contains a myriad of drugs like amla(Emblica Officinalis), grape seed (Vitis Vinifera), green tea etc. Grapes help provide the essential calories and nutrients ideal for muscle development. It also has ample antioxidants which safeguard against free radical damage, induced by exercise.

Dosage: 2 Capsules twice daily, with water after meals are recommended

5. RASARAJESHWAR RAS

Ras Rajeshwar Ras is a herbomineral formulation available in tablet form. It is made with a myriad of herbs and minerals like Suvarna yukta Rasaraj Rasa (Purified and processed Mercury ), Abhrak Satva (Purified and processed Silica), Ashwagandha  (Withania somnifera ) etc. It has got excellent results in dealing with neuro-muscular conditions such as paralysis and helps to strengthen nerves and muscles.

 Dosage:1 tablet twice daily chewed after food is recommended

6. AMRIT KALASH

It is one of the excellently recognized Rasayanas for daily health and longevity. Available in paste form,it is enriched with the excellence of 53  natural herbs and minerals like amla (Phyllanthus emblica), safed chandan (Santalum album), Haritaki (Terminalia chebula) etc and has ability to nourish the seven tissues ,provide Bala(vital strength), assisting the body to encounter illness.It also helps increasing your productivity and immunity.

Dosage: It acts most effectively on regular intake of 1teaspoon twice daily.

7. BRAHMA RASAYAN

It is a noteworthy polyherbal preparation in the form of a paste made with the goodness of Amla(Phyllanthus emblica), Shankhpushpi(Convolvulus prostratus), ghee etc . It aids in general weakness and also builds strength, stamina and treats Vata dosha. In addition to that, it has Rasayana (rejuvenating) properties and  acts as a promising antioxidant which slows down the process of cell degeneration and makes you remain healthy.

Dosage: 1 teaspoon  to be taken twice daily after food

Contact at Planet Ayurveda to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-521-4040 Or Check Website – www.PlanetAyurveda.com

Hypokalemic periodic paralysis requires proper care .This can be accomplished by avoiding causative factors and with systemic treatments. If untreated it may lead to permanent proximal weakness and even death.Don’t lose hope because Ayurveda indeed helps you in this.You can definitely choose Planet Ayurveda because your wellbeing is our happiness.

Treatment of Periodic Paralysis in Ayurveda with Herbal Remedies

Abstract

Periodic paralysis syndrome is a collection of uncommon muscle illnesses that may be inherited (genetic) or caused by a spontaneous mutation in a person’s genetic composition. Hyperkalemic periodic paralysis (hypPP) and normokalemic periodic paralysis are two of the seven to eight forms of periodic paralysis syndromes. Medications and dietary modifications may be used to treat your condition, depending on the kind of syndrome you have. You’ll learn about Ayurvedic medicine in this post.

Introduction

Periodic paralysis (PP) is a rare inherited disorder that affects a tiny fraction of the population. Muscle weakness, stiffness, or paralysis may strike without warning. It’s possible that the whole body or only one or two limbs are afflicted. PP is available in a wide range of sizes and forms. All of them have ion channel deficits at their core. These gateways may allow charged minerals like salt and potassium to enter and exit your cells. This ion flow is necessary for your muscles to operate properly. In PP, ion channels may malfunction, resulting in muscle cell dysfunction.

Ayurveda claims

Pakshaghata is an Ayurvedic term that refers to “paralysis of one side of the body,” with “paksha” referring to either half of the body, and “Aghata means paralysis” referring to deterioration of physical movements and mental wellbeing.

Periodic Paralysis

What causes your body to get paralyzed now and then?

Genetic issues cause all of the various types of PP. Ion channel faults are caused by these issues. Ion channels regulate how charged minerals (ions) including potassium, sodium, and calcium enter and exit muscle cells.

The interior of every muscle cell is covered by a coating or membrane. When your nerve instructs your muscle cell to contract, it sends a chemical signal to open a gate that allows sodium ions to enter the cell. The electrical charge inside the cell is altered by the influx of charged ions. A current wave is created in the muscle fiber as a result of this. Calcium ions leak from cells’ sacs, causing muscle fibers to contract. Potassium channels open and potassium ions are released from the cell. Muscles contract as a result of this.

PP may be caused by a variety of problems. These ion channels are affected by sodium, calcium, or potassium.

Symptoms

Depending on the kind of PP you have, your symptoms may differ. Symptoms may appear as early as infancy or as an adult. Attacks may occur often or seldom. As individuals become older, they have fewer attacks in various types of PP. Symptoms of PP include:

  • Muscle twitching may last anywhere from a few minutes to many days.
  • Muscle cramping
  • Muscle discomfort and spasm
  • Tingles on skin
  • Permanent infirmity, which is more likely to occur later in life

Diagnosis

Family history, typical symptoms, diagnostic tests, muscle biopsies, muscle chilling and/or muscular training, and recurrent electrical nerve stimulation; and, in certain cases, provocative testing are used to identify periodic paralysis syndrome. The following are some more pieces of evidence that support the diagnosis:

  • Creatinine phosphokinase levels in the blood, potassium levels, and ECG tracings that are all elevated
  • Nerves are electrically stimulated repeatedly (electrodiagnosis)
  • The afflicted muscles are cooled to 20 degrees Celsius (68F)
  • Testing by use of exercises
  • Examination with a needle electrode (examination of electrically caused muscle contraction).
  • Biopsies of muscle

All about Planet Ayurveda

Planet Ayurveda produces herbal medicines that strictly adhere to Ayurvedic principles. In the creation of our herbal supplements, only natural ingredients are employed. The main goal of this organization is to locate and eliminate the source of any disease. Periodic paralysis may be relieved with the use of a few natural remedies.

Product Description

1. Yogendra Rasa

Yogendra Rasa is a traditional concoction that helps the body maintain its Vata-Pitta balance, which means it can handle paralysis also. The ashes of gold are one of the necessary metals, and Ras Sindoor is one of the Ayurvedic medications that make the Yogendra rasa stronger than anything. It also includes Loha Bhasma (Iron Bhasma), Shuddha Mukta (Purified Pearl), and Abhrak Bhasma (Purified silica).

Dosage: 1 chewable tablet twice a day

2. Neurogenie capsules

Brahmi(Bacopa monnieri std. ext.) and Ashwagandha (Withania somnifera std. ext.) are included in the Neurogin capsules. It’s a herbal mixture that helps with periodic paralysis by treating long-term chronic pain caused by nerve damage.

Dosage: Take one capsule after each meal, with plain water.

3. Ashwagandha Ghrita

It is one of Ayurveda’s greatest nervine tonics. Long-term therapy with Ashwagandha (Withania somnifera) also improves brain strokes that result in paralysis and neuronal impairment. It also helps with muscle tiredness, neck or back stiffness, weariness, joint difficulties, and arthritis of any form.

Dosage: 1 tsp twice a day in warm water is the recommended dosage.

4. Medhya Churna

The Medhya Churna of Planet Ayurveda aids brain-related disorders such as memory, recall, and retention, which can be the symptom of a nervous disorder. Vacha (Acorus calamus), Ajmoda (Carum roxburghianum), Brahmi (Bacopa monnieri), Marich (Piper nigrum), Shankhpushpi (Convolvulus pluricaulis), and Ashwagandha (Withania somnifera), are the main ingredients in this Churna.

Dosage: 1/4 tsp once a day in warm water is the recommended dosage.

5. Neuroplan Syrup

It is a nerve tonic for people with neurological diseases and general nerve weakening that can cause periodic paralysis.

  • Shankhpushpi,(Convolvulus pluricaulis)
  • Jyotishmati(Celastrus paniculatus)
  • Mandukaparni(Centella asiatica)
  • Brahmi (Bacopa monnieri)
  • Ashwagandha(Withania somnifera)
  • Bhojpatra(Betula utilis)

Dosage: 2 tsp twice a day or as directed by an Ayurvedic practitioner

6. Dhanwantharam Oil

It strengthens muscles, ligaments, tendons, and other bodily tissues that can be weakened due to paralysis. It’s also utilized to treat Vata disorders such rheumatoid and osteoarthritis, spondylitis, headaches, and neuromuscular problems. Balamoola (Sida Cordifolia) and Cow Milk are among the plants included.

Application Method – Use on a local level.

Contact my assistant to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-521-4040 Or Check Website – www.PlanetAyurveda.com

Conclusion

These herbal combinations may be used to counteract the deleterious effects of long-term allopathic medications and treatments that cause Periodic paralysis (PP). Because allopathic treatment is ineffective. Begin by visiting Planet Ayurveda to buy and learn more about genuine Ayurvedic items. Their clinic in Mohali, Punjab, may be contacted at herbalremedies123@yahoo.com.