Category: Metabolic / Miscellaneous Disorders

Natural Cure For Galloway Mowat syndrome

Galloway Mowat Syndrome

ABSTRACT

The trend of genetic diseases is increasing nowadays. One of such conditions is Galloway mowat syndrome. This is an extremely rare congenital disorder which is manifested by a variety of physical & neurological abnormalities along with an early onset of a series of renal disorders. In this article we’ll discuss the causes, symptoms, of this syndrome along with the Ayurvedic aspect & line of management of the disease with best Ayurvedic formulations.

Galloway Mowat Syndrome

INTRODUCTION

Galloway mowat syndrome is a neurodegenerative autosomal recessive condition present since birth and characterised by the variety of features including triad of microcephaly (when the newborn baby’s head is very smaller than the normal), hiatal hernia (a condition when the part of stomach bulges through the diaphragm in the chest cavity) along with nephrotic syndrome (multiple kidney related issues).

Galloway Mowat CAUSES

Galloway-Mowat syndrome appears to be genetically inheritable and is considered to be transmitted in an autosomal recessive fashion of inheritance, which means the defective gene for the syndrome is located on autosome and the both copies of genes (one from each parent) are necessary for the disorder’s manifestation. The individual/ parent who carries one of the mutated autosomes will not show any kind of sign & symptoms related to the disorder.

Multiple genes (10 genes) are believed to be the causative factors for the clinical manifestation of this syndrome, in which the significant cases have been shown to be caused by biallelic mutations in the WDR73 gene.

One gene, LAGE3, is associated with X-linked inheritance of Galloway Mowat syndrome.

SIGNS & SYMPTOMS

The cardinal features of this disorder as discussed above are

  • Microcephaly & neurological disturbances
  • Hiatal hernia
  • Nephrotic Syndrome

Other clinical features include:

  • Cognitive impairment
  • Delayed milestones.
  • Neuropathies (various nerve related disorders)
  • Digestion issues
  • Recurrent kidney & Urinary tract infections
  • Isolated proteinuria to full blown nephrotic syndrome in early stages.
  • Severe intellectual disability
  • Epilepsy, hypotonia, ataxia, spasticity and extrapyramidal dystonia.
  • Short stature, facial disfigurement
  • Hiatus hernia
  • Ocular abnormalities (progressive optic atrophy, nystagmus and strabismus).

Ayurvedic View

Acharya Charaka and mentioned the various congenital deformities that may be produced due to mutation in genes by following phrase:


Charka Sharir sthan-Shlok

(Reference— Charka Sharir sthan- 3/17)

Garbhoutpadak beej (sperm & ovum) and beej bhag (genes/chromosomes linked encoded within the sperm/ovum) are the basic ingredient for the formation of various tissues & organs, any kind of deformity (mutation) at the level of genes (beej bhag) will be responsible for the disorders related to that particular organs & organ systems.

TREATMENT

As the disease involves renal disorders, hiatal hernia and neurological symptoms.

The line of treatment for the disease include:

  • Use of herbs that provide strength to the kidney & urinary system.
  • Herbal formulations that strengthen the brain & nervous systems.
  • Digestion stimulating drugs
  • Immune boosting drugs
  • Dhatu poshak drugs (formulation that provide adequate nourishment to the child)

Herbal remedies Galloway mowat syndrome by Planet Ayurveda

Planet Ayurveda is the best herbal formulating company that makes products which are in strict adherence to the Ayurvedic principles and formulations as suggested by our acharyas in that ancient time hundreds of decade back. The herbs & minerals used for the formulation of various medicines are obtained from 100% natural sources. These are then duly processes, purified and formulated according to ancient time tested formulas under the guidance of our expert ayurvedic physicians.

Best herbal remedies as suggested by Planet Ayurveda for this Galloway mowat syndrome are:

  1. Punarnava Mandur
  2. Reno Plan Syrup
  3. Kumar Kalyan Ras
  4. Neuro Plan Syrup
  5. Digesto Plan Syrup

GallowayMowatsyndrome

PRODUCT DESCRIPTION

1. Punarnava Mandur

Punarnava Mandur is a classical preparation available in tablet form. The main ingredient here is Punarnava (Boerhavia diffusa) which is the best single drug for kidney, beneficial in improving kidney functions by providing strength to the kidney muscles. Along with it it also contains trikatu (combination of three pungent drugs i.e. Piper nigrum, Piper longum & Zingiber officinale) and mandur (detoxified iron ore) which collectively act as blood purifiers and help in the formation of new blood cells. Thus, reducing the load on the kidney this formulation helps in Galloway Mowat Syndrome.

Dosage: 1 tablet twice daily after feeding. (to be crushed well and then used with Reno Plan syrup)

2. Reno Plan Syrup

Reno Plan Syrup is the herbal syrup made by our team experts by combining the goodness of many herbs that promotes the kidney functions. The main ingredients of this syrup includes Punarnava, gokshura (Tribulus terrestris) and varun (Crataeva nurvala) which are the best herbal diuretics and are useful in preventing or treating various urinary tract infections. The distorted renal functions in this syndrome are well managed by the ingredient trin panchmool ghan vati which is an ayurvedic formulation made using 5 roots of grasses that are mutravirechak in action. The other ingredients such as Kalmegha (Andrographis paniculata), kaasni (Cichorium intybus) etc. aids in scavenging the free radicals by their antioxidant properties.

Dosage: 1 teaspoon twice daily after feeding.

3. Kumar Kalyan Ras

Kumar Kalyan Ras is the herbomineral compound which is described in the ancient Ayurvedic texts. This preparation is used in Galloway Mowat Syndrome due to the dhatu poshak (nourishing action on depleted bodily tissues) action of its ingredients. The ingredients of Kumar Kalyan Ras include swarna bhasma (purified ash of gold), abhrak bhasma (purified and processed ash of mica), shuddha parada (purified form of mercury), mukta bhasma (calx of pearl), loha bhasma (purified ash of iron) and makshika bhasma (purified extract of copper – iron pyrite) along with Kumari Rasa (Aloe vera’s juice extract). These calx of purified minerals are well efficient to reach upto the cellular level and nourish the various body tissues. Along with aloe vera which also facilitates in enhancing the immune system & maintaining hormonal balance.

Dosage: One tablet daily (to be chewed or crushed & used with syrup), after feeding.

4. Neuro Plan Syrup

Neuro Plan Syrup is the amazing poly herbal syrup made on the guidance of our expert team for the various neurological disorders. The herbs used in the syrup aids in calming the mental dosha i.e. raja & tama dosha. In this case i.e. Galloway mowat Syndrome is a neurodegenerative disorder in which there is a gradual decrease in neurological functions. Neuro Plan syrup’s ingredients such as Brahmi (Bacopa monnieri), Jyotishmati (Celastrus paniculatus), Mandukaparni (Centella asiatica) and Shankhpushpi (Convolvulus pluricaulis) etc. are the best medhya dravya (nervine tonics) and they strengthen the nervous system and also make the internal environment favourable for the proper functioning of brain & brain cells.

Dosage: 1 teaspoon two times a day after feeding.

5. Digesto Plan Syrup

Digesto Plan Syrup is the best herbal remedy for digestive issues & providing strength to abdominal musculature. In this case the major manifestation also includes hiatal hernia. So, this syrup will support the digestion of the baby & aiding in strengthening the muscles of the abdomen to prevent hernia from proceeding further. The ingredients include trikatu (Sonth, Maricha, Pippali) along with triphala i.e. combination of three fruits amalaki (Embilica officinalis), bibhitaki (Terminalia bellirica) and haritaki (Terminalia chebula) and other such herbs will make the digestion faster and also promote the cleansing action which will decrease the excessive  load or distension of the abdomen, which will prevent the hernia to pop out more further. Despite that it promotes the healing of hernia side by side by providing strength to those muscles.

Dosage– 1 tsp twice daily after feeding

CONCLUSION

It is very unlucky to have such a rare neurodegenerative disorder that affects multiple systems of the body. Despite giving steroids to the young child at very early stages of life which have tons of adverse effects in the later stages of life, use of such herbal based medicines is the best alternative for Galloway Mowat syndrome. For more information kindly visit www.PlanetAyurveda.com

Herbal Remedies For Trigeminal Neuralgia

Abstract

Trigeminal Neuralgia is a pain disorder that affects the trigeminal nerve. This is a disease of the facial nerve supply. This disease is rare and it mostly affects older adults, especially women. The nervous system is a highly complex part of the body that coordinates its action and sensory information by transmitting signals from and to different parts of the body. There are many nervous disorders and trigeminal neuralgia is one of them. The pain episode of Trigeminal Neuralgia occurs and then may not return for years and also can be triggered by emotional shock, facial treatment, and routine activities involving facial movement etc. Further in this article we are going to discuss trigeminal neuralgia and its Ayurvedic management through herbal remedies.

Trigeminal Neuralgia

Introduction

Trigeminal neuralgia is a rare, extremely painful nervous condition that affects the face. This condition is a long term pain disorder that affects the trigeminal nerve which is responsible for sensation in the face and motor functions such as biting and chewing. The pain felt by the individual is often extremely severe and debilitating. The term trigeminal is coined for a nerve originating in the cranium i.e. the top of the face, and divides and runs symmetrically on both sides of the face and that nerve is known as trigeminal. Its branches connect the eyelids, the eyes, the cheeks and the nose, and then the upper and finally the lips and the lower jaw. Therefore this disease mainly affects the face.

Ayurvedic Aspect of Trigeminal Neuralgia

In Ayurveda, we can correlate this disease with Anantavata. Acharaya Sushuruta said that when tridosha (Vata, Pitta and kapha) vitiate the Manya or greeva (the region of either sides of neck) due to excessive weeping, anger, rough and cool items eating, fasting or taking less food then it will produce severe intolerable pain at neck, in the eyeball, in the frontal region, root of the nose and in temporal region. At the end it will cause lockjaw, eye diseases and shivering of jaws (Ganda parshava kampa).

Etiology/Causes

The exact cause of Trigeminal Neuralgia is not known. But researchers thought that it can occur as a result of aging or it can be related to the damage to the myelin sheath that protects certain nerves or it can be related to multiple sclerosis. Some doctors also said that it can also be caused by a tumor compressing the trigeminal nerve.

Clinical features/Signs and Symptoms

The patient of Trigeminal neuralgia can experience one or many of the following symptoms

  • An intense shooting pain
  • Attacks of pain for hours or even days
  • A burning sensation
  • Constant pain in one side of the face
  • Pain in lips, jaws and gums
  • Pain in eyes and forehead
  • Pricking pain in the face
  • Pain attacks get frequent and more severe with time

Triggering Factors

Various factors contribute to the aggravation of this condition or its symptoms in an individual. Such factors are called triggering factors. The following factors are considered as triggers for trigeminal neuralgia

  • Touching the face
  • Chewing gums
  • Eating
  • Drinking
  • Brushing the teeth
  • A cold wind
  • Laughing
  • Smiling
  • Frowning
  • Excessive talking
  • Washing the face
  • Putting on makeup
  • Repeatedly eating

Diagnosis

This disease is mainly diagnosed based on the description of the pain that include type and location of the pain and also the triggering factors. Then a doctor may conduct some imaging and scanning tests to diagnose this disease further. Some neurological examinations may reveal or confirm this disease.

Complications

If this condition is left untreated then the complications include loss of sensation in the face.

Ayurvedic Management of Anantavata

In Ayurveda it can be manageable through nasya yoga, anjana yoga, lepa yoga and some oral remedies

  • Nasya yoga: we can use Snehan nasya, ksheeri sarpi (Ghee prepared from milk), dhanwantari taila, ksheera bala taila, Shadbindu taila, Anu taila.
  • Anjana yoga: We can use Chandrodaya varti and nagarjuna varthi.
  • Lepa yoga (External application): We can use the Paste of surajmukhi beej + suryamukhi swaras, Sarivadi lepa and haridra lepa.
  • Oral remedies: For orally we can use the following classical medicines.
    • Shirashooladi Vajra Ras
    • Ekaangaveer Ras
    • Sudhanidhi Ras
    • Godanti Bhasma + Sphatika Bhasma
    • Saptamrit Loha
    • Vata Vidhwansan Ras
    • Triphala Ghrita

Herbal Remedies for Trigeminal Neuralgia

Planet Ayurveda is a leading company of herbal products. They manufacture various herbal remedies by using the standardized extracts of potent herbs and also they are manufactured by using the ancient time-tested formulas. This company is GMP and internationally certified. This company offers the following herbal remedies for Trigeminal Neuralgia

  1. Boswellia Curcumin
  2. Hakam Churna
  3. Ashwagandha Capsules
  4. Yograj Guggul

trigeminal-neurolgia

Products Description

1. Boswellia Curcumin

This is a poly herbal formulation of Planet Ayurveda. This is an effective combination of anti-inflammatory herbs such as Shallaki (Boswellia serrata) and Curcumin (Curcuma longa). This is a very potent herbal remedy for trigeminal neuralgia. It reduces the inflammation and pain from the affected area. Curcumin is an excellent pain reliever herb hence helpful in reducing pain which is the prominent sign of trigeminal neuralgia. It is also very beneficial in joint pain.

Dosage: 1 capsule twice a day after meals with plain water.

2. Hakam Churna

This is classical herbal formulation. This formulation is a combination of great herbs that are potent to fight against digestive disorders. This churna has an ability to retrieve the normal digestion by alleviating the Vata dosha which is also responsible for neurological disorders. This is also known as Tridoshic rasayan. This formulation is made from herbs like Chandershoor (Lepidium sativum), Kalonji (Nigella sativa), Methi (Trigonella foenumgraecum) and Ajwain (Trachyspermum ammi). It is very useful in painful joints, stiff joints, morning stiffness, back pain and all other pain disorders.

Dosage: 1 tsp twice a day with lukewarm water before meals

3. Ashwagandha Capsules

This is a single herbal formulation. It is a great nervine tonic that enhances physical as well as mental health. These capsules are made from the standardized extracts of Ashwagandha (Withania somnifera). This herb is very useful in this condition as it pacifies vata dosha which is the reason for all neurological disorders. Vata dosha governs all the movement in the body including the movement of nerve impulses throughout the nervous system. Ashwagandha is useful in debilitating conditions like fatigue, stress, anxiety, palpitation and nervous breakdown.

Dosage: 1 capsule twice a day after meals with plain water.

4. Yograj Guggul

This Ayurvedic classical formulation is best for the treatment of vata dosha. It is used in various musculoskeletal disorders. It pacifies vata dosha and helps in alleviating the symptoms of this condition such as pain. It is prepared from potential herbs such as Chitrak (Plumbago zeylanica), Pippali (Piper longum), Vidang (Embelia ribes), Pushkarmoola Inula racemosa) etc. It is traditionally used in Ayurveda for painful joints and muscles. It rejuvenates muscle strength.

Dosage: 2 tablets twice a day after meals with plain water

Conclusion

At last we concluded that this disease is well managed by the Ayurvedic herbs. The herbal products of Planet Ayurveda are very safe and chemical and preservative free. These products mainly work on alleviated Vata dosha that is responsible for all neurological disorders and hence helpful in treating trigeminal neuralgia. For further information you can visit on www.planetayurveda.com