Category: Anemia

Herbal Remedies for Paroxysmal Nocturnal Hemoglobinuria

Abstract

The destruction of red blood cells is known as hemolysis and this can be caused by different reasons. Hemolysis is responsible for releasing hemoglobin into the bloodstream and normal blood cells have 120 days of lifespan. When they break down they are released into the circulation by the spleen. There is a rare medical condition that results in increased destruction of the blood cells known as Paroxysmal Nocturnal Hemoglobinuria. Through this article, we are going to discuss this rare blood condition in detail and its help through the Ayurvedic condition.

Introduction

Paroxysmal Nocturnal Hemoglobinuria is a rare acquired condition of the blood and can result in death. It is mainly characterized by clotting of blood (thrombosis), increased destruction of blood cells (hemolytic anemia), and impairment of bone marrow function. It was first discovered by a German physician known as Paul Strubing in 1852 to 1915.

  • Epidemiology: – It is sporadic, and one in every one million people is affected with PNH.
  • 25% of females are affected with PNH and most of them are discovered during the time of their pregnancy

Sign and Symptoms

symptoms of Paroxysmal Nocturnal Hemoglobinuria

There are wide ranges of treatment seen in Paroxysmal Nocturnal Hemoglobinuria and sometimes is not noticed for months or years

This includes signs like

  • Weakness and fatigue
  • Unusual bleeding or bruising all over the body.
  • Difficulty in breathing
  • Flu-like symptoms or reoccurrence of infections.
  • Unable to control bleeding even from small cuts or wounds
  • Headache that is very severe
  • Fever because of infection
  • Blood clots

Other issues like back pain and abdominal pain are also noted. Some of the classic signs are that the urine appears bright red in 50 percent of patients. The hemoglobinuria is especially very noticeable in the morning. The attack of hemoglobinuria can be caused by consumption of alcohol, infections, stress, exercise, and some certain type of medications.

Blood clots can be formed in veins and it is one of the leading causes of death in a patient with Paroxysmal Nocturnal Hemoglobinuria. The common sites for the blood clots are the sagittal vein and hepatic vein.

Causes

The main cause for PNH occurs when there is a mutation of a gene known as PIG-A present in the bone marrow stem cells. Stem cells are responsible for giving rise to the mature blood elements which include red blood cells, these cells are helpful in carrying oxygen to the tissues and also have white blood that helps in fighting the infection.

In patients with Paroxysmal Nocturnal Hemoglobinuria, the stem cell moves the PIG-A mutated gene to all the cells making the stem cells abnormal.

Pathophysiology

All the cells in the body have protein which is attached to the membranes and helps in communication between the two cells. These proteins are physically connected to the membrane of cells in many ways, commonly with glycolipids known as Glycosyl phosphatidylinositols. In patients with PNH the glycolipid protein is defective.

Herbal Medicine Provided By Planet Ayurveda for Paroxysmal Nocturnal Hemoglobinuria

Planet Ayurveda provides herbal medicine that is 100 percent pure, natural, and vegetarian. All the herbal medicine made in Planet Ayurveda is clinically tested and made under the supervision of an MD Ayurvedic Doctor. Each herbal medicine is clinically tested making them safe to use and free of side-effects

Paroxysmal nocturnal hemoglobinuria

Treatment of Paroxysmal Nocturnal HemoglobinuriaHere is the list of Herbal Medicine

  • Hemo Plan Syrup
  • Plato Plan Syrup
  • Giloy Capsules
  • Spirulina Capsules
  • Immune booster
  • Manjishtha Capsules

Product Description

1. Hemo Plan Syrup

It is a herbal syrup formulated with herbs like

  • Shatavari (Asparagus racemosus)
  • Saariva (Hemidesmus indicus)
  • Draksha (Vitis vinifera)
  • Saariva (Hemidesmus indicus)
  • Ashwagandha (Withania somnifera), and many more.

The syrup is a gift from nature that helps in removing toxins from the blood and also a natural source of iron. Hemo plan also helps in removing ailments like weakness, pain, bruising, etc which is very commonly seen in patients with Paroxysmal Nocturnal Hemoglobinuria

Dosage:- One teaspoonful twice daily with water after meals.

2. Plato Plan Syrup

This herbal syrup helps in improving the count of platelets as it formed from herbs like Giloy (Tinospora cordifolia), Eranda Karkati (Caricapapaya), Draksha (Vitis vinifera), etc. Plato plan helps in giving strength to the body and is packed with antioxidants that helps in preventing the platelets from getting damaged. It is also very useful in flushing out the toxins from the blood.

Dosage:- One teaspoonful twice daily with water after meals.

3. Giloy Capsules

It is one of the best herbal medicines packed with anti-inflammatory and antipyretic properties as it is made from an excellent herb like Guduchi (Tinospora cordifolia). It is one of the wonderful herbs in removing any type of fever and lowering down the inflammation from the body. Giloy is also very good for removing ailments related to skin, infections and best for people who have weak immunity.

Dosage:- One capsule twice daily with water after meals

4. Spirulina Capsules

These capsules are made from algae known as Spirulina (Spirulina platensis)  which is rich in nutrients like vitamins, proteins, minerals, chlorophyll, and omega-3 fatty acids. This herbal medicine helps in maintaining the good health of the Cardiovascular system

Dosage:- One capsule twice daily after meals with lukewarm water.

5. Immune booster

As the name describes it helps in making the immunity stronger and powerful as it is formed from herbs like

  • Grapeseed (Vitis vinifera)
  • Amalaki (Emblica Officinalis)
  • Cow colostrum (Bovine colostrums)
  • Bhumi Amla (Phyllanthus niruri)

It is very useful for people who have recurrent infections and have an immuno-compromised state. The immune booster helps in fighting infections, aging, asthma, liver inflammation, and many more

Dosage:- One capsule after meals twice daily with water.

6. Manjishtha Capsules

This is made from the extract of the single herb known as Manjishtha (Rubia cordifolia) which is well known for relaxing the body and reducing stress as well as anxiety. These capsules are rich in antioxidants and are useful in purifying the blood and also treating all kinds of fever present in the body

Dosage:- One capsule twice daily after meals with water.

Contact my assistant to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214030

Conclusion

Paroxysmal Nocturnal Hemoglobinuria is a very rare disease and can result in a life-threatening situation. So, it is important for the patient to be treated carefully by a good Doctor. Allopaths have no treatment for the disease but Ayurveda provides their herbal medicine which is very useful in treating the disease. All the medicine mentioned above is best for treating Paroxysmal Nocturnal Hemoglobinuria as they remove the root cause of the disease.

Natural Remedies for Sideroblastic Anemia (blood disorder)

Abstract

In this article our main topic of discussion will be a very common blood disorder known as sideroblastic anemia. It is a type of anemia and has a great prevalence rate. Ayurveda deals with such ailment by doing detailed study of individuals prakriti (nature), and then we uses medication according to that by following basic principles of ayurveda tridosha theory (three principle energies of our body- vata, pitta and kapha) and panchamahabhuta theory (five basic elements of life- akash (sky), vayu (air), agni (fire), jal (water) and prithvi (mother earth). So let’s start discussing this in more detail.

Introduction

Sideroblastic anemia is a type of anemia in which bone marrow starts producing ringed sideroblasts (they are nucleated erythroblasts that are precursors to mature red blood cells) instead of normal red blood cells (erythrocytes). In a normal healthy person these sideroblasts are present in bone marrow and enter blood circulation after maturing into red blood cells. So this process of maturing and entering into the main blood stream of sideroblast got affected in sideroblastic anemia.

As per ayurveda we can correlate this with “pandu roga”. In this pitta dosha gets aggravated in the body due to those body tissues starting undergoing inflammatory reactions that make the body weak and lethargic. This leads to deterioration of varna (colour), bala (strength), sneha (protective fat layer of the body) and ojas (immunity power).

causes of sideroblastic anemia

Etiological Factors

These are the main causes (nidan as per ayurveda) that results in formation of an ailment.

In sideroblastic anemia the common causes are as follow

  • Hereditary involvement- in most of the cases congenital sideroblastic anemia occurs due to presence of x-linked sideroblastic anemia or autosomal recessive sideroblastic anemia.

Due to the presence of following genetic syndromes

  • Ataxia
  • Myopathy
  • Pancreatic insufficiency
  • Excessive alcohol consumption
  • Deficiency of vitamin B6 and copper
  • Lead poisoning.
  • Disorders of bone marrow.
  • Malnutrition

According to Ayurveda

1. Ahaaraj nidan (dietary causes)

  • Intake of amla (sour), lavan (salty), kshaar (alkali) and ushna (hot) food items.
  • Consumption of virudh and asatmya bhojan
  • Use of tikshna and vidagdha food substances.
  • Pramitashan

2. Vihaaraj nidan (lifestyle related causes)

  • Ati vyayam (over use of physical activities)
  • Divashayan (who sleeps during day time)
  • Ati maithun (excessive use of sexual activities)
  • Veg dharna (suppression of natural urges)

Prodromal Symptoms (Purvarupa)

These are the common complaints or early signs/symptoms that indicate onset of a disease.

Our acharya had clearly mentioned this in our ancient classical text and are as follows.

  • Palpitation
  • Dryness of skin
  •  No sweating
  • Fatigue
  • Excessive salivation
  • Malaise
  • Desire to eat clay/ mud
  • Swelling around the eyes
  • Yellowness of urine and stool
  • Indigestion.

Clinical Features

It includes the signs and symptoms. Asymptom means the general complaints along with patients present in front of the physician. Signs: It means what a physician notices himself by observing the patient’s condition.

  • Paleness in the skin.
  • Fatigue and malaise
  • Dizziness
  • Indigestion
  • Anorexia (loss of appetite)
  • Vertigo
  • Cramps in legs

According to Ayurveda

  • Pallor of skin
  • Scanty blood
  • Fat deficiency
  • Loss of glow
  • Tinnitus
  • Generalized body weakness
  • Anorexia (loss of appetite)
  • Fatigue
  • Vertigo
  • Fever
  • Exertional dyspnoea
  • Fall of hairs
  • Hate cold environment
  • Excessive sleep
  • Speech becomes feeble in nature.
  • Cramps in calf region

Types of sideroblastic anemia

1. Type 1 sideroblasts: Presence of less than 5 siderotic granules in the cytoplasm of the cell.

2. Type 2 sideroblasts: There will be a presence of 5 or more siderotic granules in this type.

3. Type 3/ ring sideroblasts: Presence of 5 or more granules in a perinuclear position that covers the one third portion of nuclear circumference. This type is included in sideroblastic anemia whereas the previous first two types are included in non sideroblastic anemia.

Complications

It means certain conditions that might occur in future due to presence of sideroblastic anemia for a long term basis.

  • Anorexia
  • Excessive thirst
  • Vomiting
  • Headache
  • Indigestion
  • Emaciation
  • Fainting
  • Malaise
  • Cardiac pain
  • Exertional dyspnoea
  • Diarrhea
  • Cough
  • Burning sensation
  • Hoarseness of voice

Diagnosis

Detailed physical examination of the patient by using inspection, palpation, percussion and auscultation techniques.

Laboratory findings: Complete blood count test

  • It shows a high level of serum iron and increased ferritin levels.
  • Decreased total iron binding capacity.
  • On blood smear- Presence of ringed shaped sideroblasts are seen.

According to Ayurveda – The two most preferred diagnostic procedures used by a physician are as follow

Trividh pariksha (Group of 3 diagnostic procedures)

  • DarshanDiagnosis is made by visual examination of the symptoms.
  • Sparshan-Physician uses tactile examination to evaluate whether skin is cold/hot
  • Prashan– Physicians ask direct questions from the patient, to evaluate the root cause of the disease i.e. history taking.

Asthavidh pariksha (set of 8 examination procedure)

  • Nadi pariksha– By palpating the pulse rate of the patient.
  • Mutra pariksha– By examining the urine of the patient.
  • Mal pariksha– By stool examination.
  • Jivha pariksha– By examining the tongue whether coated or not.
  • Shabad pariksha– By listening to the natural sounds within the body like intestinal sound (peristalsis) sounds of moving body fluids.
  • Sparsh pariksha– By observing the patient skin texture whether it is cool, wet or dry.
  • Drik pariksha– When a physician inspects patient symptoms through his/her eyes.
  • Akriti pariksha– When a physician evaluates the general appearance of a patient whether he/she looks dull, lethargic or fatigued etc.

Management

According to Ayurveda the main line of treatment is as follow

  1. Nidan parivarjan chikitsa (avoiding the root cause of disease) – This treatment modality had been given utmost importance in our ancient text. As according to ayurveda
  2. Sanshodhan chikitsa (detoxification procedure)-  As per charaka chikitsa 16/40-

We need to follow below listed therapeutic procedures

(i). Abhiyantra sanehan– Smoothing the internal dosha’s of our body by using herbally medicated ghrita/oil.

Example

  • Panchagavya ghrita
  • Mahatikta ghrita
  • Draksha ghrita

Dosage: 10-20 ml with warm water after meals.

(ii). Tikshan sanshodhan– In this tikshna herbs are used for vaman and virechna karma

  • Vaman (emesis) – emetic medicines are given to the patient to take out the vitiated dosha of the body.
  • Virechana (purgation) is the best technique to release out the pitta dosha from    the body by anal route. We can use- gomutra and haritaki churna for this.

(iii). Basti- In this liquid form of medicine is put inside the body via anal route with the help of specially made basti yantra (instrument). In sideroblastic anemia we will use rakta basti specifically.

3. Sanshaman chikitsa (Oral medications) – In this use of medication by oral route is done.

1. Rasa/bhasma/loha/mandur

  • Punarnava mandur
  • Navayas loha
  • Yograj
  • Loha bhasma

Dosage: 125-250 mg with honey or water after meals.

2. Vati

  • Arogyavardhini vati
  • Mandur vatak

Dosage: 250-500 mg with honey or water after meals.

3. Asava

  • Lohasava
  • Drakshasava

Dosage: 20-40 ml with equal amount of water after meals.

4. Avaleha

  • Dhatri avaleha
  • Drakshavaleha

Dosage: 10-20 gm with water after meal.

List of Planet Ayurveda Herbal Formulations

Herbal Remedies for Sideroblastic Anemia

Planet ayurveda has been serving people worldwide for the past 20 years with their holistic approach to healing. Their herbal products are made under the guidance of ayurveda experts and are very effective in maintaining a healthy and sound body as they are completely pure and organic in nature. They offer various herbal formulations that works really well in condition like sideroblastic anemia, some of them are as follow:

  1. Green Essentials
  2. Spirulina capsules
  3. Punarnava mandur
  4. HemoPlan syrup
  5. Suvarna Basant malti ras

Products Description

1. Green essentials

This herbal formulation contains potent blend of medicinal herbs such as

  • grape seed (Vitis vinifera)
  • wheat grass (Triticulum aestivum)
  • spirulina (Spirulina platensis)
  • green tea (Camellia sinensis)
  • amla (Embllica officinalis)

All the herbs present in this herbal formulation have great immunity enhancing properties. It also contains a good amount of antioxidants and other necessary nutrients that will assist very profoundly in sideroblastic anemia.

Dosage: 1 capsule twice daily with plain water after meals.

2. Spirulina capsules

This capsule contains a pure form of spirulina (Spirulina platensis). It is a rich source of various healthy micro and macro nutrients. It is known for its immunity enhancing property. It also has anti cancerous properties so helps in maintaining overall strength and stamina of patients of sideroblastic anemia.

Dosage: 1 cap twice daily with plain water after meal.

3. Punarnava mandur

This herbal formulation is imbued with plenty of therapeutic actions as it contains punarnava (Boerhaavia diffusa) which is very effective in increasing the digestive power of the body. Other herbs present in the formulations such as

  • pipali (Piper longum)
  • sunthi (Zingiber officinale)
  • amalaki (Emblica officinale)
  • haridra (Curcuma longa) etc

Contain anti-inflammatory antifungal properties so it works really well in patients suffering from sideroblastic anemia.

Dosage: 2 tabs twice daily with plain water after meal.

4. Hemoplan syp

This herbal syrup is potent blend of various medicinal herbs such as

  • manjishtha (Rubia cordifolia)
  • shatavari (Asparagus racemosus)
  • gorakhmundi (Sphaeranthus indicus)
  • ashwagandha (Withania somnifera)
  • draksha (Vitis vinifera)
  • sariva (Hemidesmus indicus).

It has great blood enhancing properties that will help in increasing hemoglobin concentration in the blood. It also helps in providing strength and stamina to patients suffering from sideroblastic anemia.

Dosage: 2 tsf twice daily after meal.

5. Suvarna Basant malti ras

This herbomineral formulation contains properties like anti-inflammatory (reduce inflammation). It helps in boosting up the immunity of our body by balancing tridosha. It also possesses “rasayan” property that rejuvenates the body channels and helps in lengthening the lifespan of sideroblastic anemia patients. It contains marich (Piper nigrum), kharpara bhasma (calamine in an incinerated form), shuddha hingula (cinnabar in a purified form), swarna bhasma (gold in an incinerated form) etc.

Dosage: 1 tab twice daily with plain water after meal.

Contact my assistant to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214030 Or Check Website – www.PlanetAyurveda.com

Conclusion

We can now conclude that in an ailment like sideroblastic anemia ayurvedic herbs works very efficiently. In sideroblastic anemia the main culprit is the elevated Pitta dosha so our main concern is to deal with it intrinsically. For Ayurvedic treatment, you can consider choosing Planet Ayurveda as we have been serving mankind with our holistic approach of healing. You can directly visit us at our clinic at Mohali, Punjab or can send your queries on our official email id- herbalremedies123@yahoo.com