Category: Hereditary motor sensory neuropathy

February 3, 2023

Herbal Remedies for Progessive Supranuclear Palsy Treatment

ABSTRACT

Progessive supranuclear palsy is a uncommon brain disorder that causes difficulty in walking, eye movement, and balance. The brain is an organ made up of a large number of nerve tissues that is protected within a hard structure known as the skull. It mainly includes functions such as it helps in regulating blood pressure and breathing, releases hormones and processes sensory information. Brain health is an emerging and growing concept that provides plasticity, functioning across life.

Numerous interconnected social and biological genetics play an important role in normal functioning of the brain. The cerebrum is the largest part of the brain and divides into 2 hemispheres. Each hemisphere is divided into regions called lobes. There are 4 lobes- Frontal lobes, parietal lobe, temporal lobe, occipital lobe. There are many conditions affecting the brain such as Cerebrovascular injury such as strokes, Neurodegenerative disorders such as Parkinson’s disease, dementia, and many more. It includes symptoms like headache, dizziness, speech problems, seizures, dilation of one or more pupils. We will study about its causes, symptoms, and its ayurvedic aspect further in this topic.

INTRODUCTION

Progessive supranuclear palsy is a degenerative disease which involves the deterioration of the brain cells which further causes loss of balance, slowing of movements, difficulty in moving eyes. The cause of this disease is unknown but there is accumulation of a protein called Tau within the brain. Sometimes it can be misdiagnosed with Parkinson’s disease. This condition keeps on worsening over time. Neurodegenerative refers to the collapse of the nervous system where there is death of numerous cells. Supranuclear refers to damage to localized nuclei in the brain. It is also known as Steele Richardson Olszewski syndrome. It worsens over time and leads to life threatening conditions such as pneumonia, swallowing problems. Supranuclear refers to the region of the brain above 2 small areas called nuclei. It is more commonly seen in men than women and it affects the middle aged or older people.

Progessive Supranuclear Palsy

CAUSES

  • Progessive supranuclear palsy occurs mainly when brain cells are damaged resulting in buildup of protein known as Tau.
  • Tau occurs in the brain and usually breaks down before it reaches a high level.
  • In people who are suffering from Progessive supranuclear palsy the build up protein doesn’t break down and forms harmful clumps in the brain.
  • Clumps of tau are progressively seen in neurodegenerative disorders such as in Alzheimer’s disease.
  • Mitochondrial dysfunction can also cause progessive supranuclear palsy.
  • Substantia nigra is the most affected part of the brain where palsy symptoms are visible.
  • Clumps formed in the brain cells damages the neurons

SIGNS AND SYMPTOMS

  • Change in behavior such as irritability
  • Slurred speech
  • Difficulty in swallowing
  • Muscle stiffness
  • Loss of balance while walking- Tendency to fall back is an early symptom of this disease.
  • Depression
  • Dizziness
  • Rigid facial muscle
  • Urine incontinence
  • Sleep disruption
  • Constipation
  • Poor eyelid function
  • Contracture of the facial muscles.
  • Dementia

COMPLICATION

  • Falling which could lead to fractures, brain injury.
  • Difficulty focusing your eyes
  • Problems during inhaling food or liquid into the airway (aspiration).
  • Pneumonia which is the most common cause of death in progessive supranuclear palsy.
  • Impulsive behavior

TYPES

It is divided into following categories

  1. Classical Richardson syndrome
  2. Progessive parkinsonism and Progessive supranuclear palsy -pure akinesia with gait freezing
  3. Progessive supranuclear palsy – C
  4. Progessive supranuclear palsy induced by Annonanceae (known as custard apple)

DIAGNOSIS

  • Progessive supranuclear palsy diagnosis is difficult as it has signs and symptoms similar to Parkison disease. So doctor suspect following:
  • Don’t have tremors
  • Unexplained falls
  • Response to parkinson medication
  • MRI (magnetic resonance imaging)

TREATMENT

  • Parkisnson’s disease medications- It increases the level of brain chemical which controls the muscle movements, the effectiveness of this medication is temporary lasting for 2-3 years. Medications include- Levodopa, Levodopa with anticholinergic agents. 
  • Onabotulinumtoxin A- Is injected in small doses into muscle of your eyes as botox helps muscles to contract which improves spasms of eyelid.
  • Prism lenses- These lenses are very helpful as they ease the problems with looking downwards. These lenses allow people to look downwards without rolling their eyes downwards.
  • Physical therapy- It helps to improve balance, facial exercise, Gait balance and training helps to relieve symptoms of progessive supranuclear palsy.
  • Mental health- It is counseling with a therapist who improves the copying technique.
  • Antidepressant medications- The most commonly antidepressant medications are- Fluoxetine, Amitriptyline (Elavil).
  • As progessive supranuclear palsy worsens, the patient can’t swallow which prevents him/her from eating and drinking so surgery is recommended (GASTROTOMY).  

AYURVEDIC MANAGEMENT

Progessive supranuclear palsy is caused due to vitiated vata dosha. Vata dosha is responsible for control of all the nervous functions in the body. Vata dosha is a tantra which runs the machine of our body. When vata dosha gets disturbed it drives the body crazy, disturbs the events in the body and causes diseases. Vatavyadhi is divided into 2 parts- Dhatukshayajanya avastha pain is reduced by touching. But in Margavrodhajanya pain is aggravated after touching. Due to intake of vata aahara and vihaar, vata dosha gets vitiated which gets stuck in the rikta strotasa and loses their qualities like smoothness and stickiness. On occupying the srotas this vitiated vata will produce Ekanga and Sarvanga diseases. Two pathology plays an important role in vatavyadhi there is decrease in dhatu and srotas become empty, but in margavarodhjanya vatavyadhi there is obstruction due to dhatu, maal and vata dosha gets stagnated which leads to dysfunction in organs. 

CAUSATIVE FACTORS OF VATA VYADHI

  • Intake of dry food, cold food.
  • Improper administration of vamana, virechana.
  • Fear
  • Irritation
  • Excessive consumption of spicy foods.

PREMONITORY SYMPTOMS

  • Stiffness of joints
  • Horripilations
  • Lameness
  • Sleeplessness
  • Numbness in body parts
  • Convulsions
  • Pricking type of pain.

TREATMENT

  • Snehan
  • Swedan
  • Mridu shodhana (virechana)
  • Deepan and Pachana sneha
  • Massage with medicated oils
  • Hot and fresh foods
  • Pouring of medicated oil in the form of seka
  • Consume sour, sweet food

HERBS USEFUL FOR PROGESSIVE SUPRANUCLEAR PALSY

  • Turmeric- Turmeric (Curcuma longa) rectifies the metabolic fire due to its ushna veerya which further cleanses and detoxifies the ras, enables free circulation to each part of the body and restores the normal functioning of the body. Haridra removes the blocked channels and enables the free movement of vata and makes dhatu nourished and replenished.
  • Shilajit- Shilajit plays an important role in treating urinary disorders, skin disease, worms infestation, mental disorders. Shilajit plays an important role as it has fulvic acid which is preventing Tau protein from aggregating so it is useful in Alzheimer’ disease and is reducing anorexia. It helps to maintain blood pressure, strengthens the skeletal system, brings energy and stamina.
  • Amalaki- Amalaki is the best anti-aging herb which balances all the three doshas in the body, useful in bleeding disorders, fever, and has a rejuvenative property.  It is rich in vitamin C and antioxidants which nourish the tissues. Amalaki promotes healthy circulation, tonify the muscles, enhances memory and brings a sense of calm to mind. It clears and detoxifies the system known as Rasayana herb.

HERBAL REMEDIES BY PLANET AYURVEDA FOR PROGESSIVE SUPRANUCLEAR PALSY

Ayurvedic medicines treat the disease as the root cause for maintaining a healthy life. Planet ayurveda is a brand which has been serving pure extract in the form of tablets, capsules, powder which are prepared under guidelines of Ayurvedic board. The medicines prepared are free from any chemicals and preservatives, are 100% pure and vegetarian. Ayurvedic medicine reduces the risk of recurrence of disease and causes no side effects of the treatment as it is pure plant based extracts.

PRODUCTS LIST

  1. VRIHAT VATCHINTAMANI RAS
  2. MUSLI STRENGTH
  3. YOGRAJ GUGGUL
  4. ASHWAGANDHA CAPSULE
  5. NOURISH MAXX
  6. BRAHMI CAPSULE
Herbal Remedies for Progressive Supranuclear Palsy
Progressive Supranuclear Palsy

PRODUCTS DESCRIPTION

1. Vrihat Vatchintamani Ras

Vrihat vatchintamani ras is one of the classical formulations which is effective in balancing vata dosha. It is prepared in the form of tablets by planet Ayurveda using ingredients like- Swarna bhasma (Calx of Gold), Rasa Sindoor (Red sulphide of mercury), Praval bhasma (Calx of coral) and many more. These tablets are helpful in maintaining cardiac health by strengthening the muscles, used in a variety of diseases like diabetes, splenomegaly, hypertension. This tablet has rajata bhasma  which is an excellent drug for mental health disorders and has antidepressant property. 

Dosage– 1 tablet twice daily to be chewed with plain water after meals.

2. Musli Strength

Musli strength is a great formulation prepared by planet ayurveda in the form of capsules using ingredients like- Safed Musli (Chlorophytum borivilianum) Gokshura (Tribulus terrestris). It helps in strengthening of the body and bone, uplifts the power of the reproductive system as it increases the quality and quantity of sperms. It has gokshura which is a diuretic and has cleansing properties on the urinary system and on lithotriptic activity. Tribulus has wound healing properties and balances tridosha.

Dosage– 1 capsule twice daily with plain water after meal

3. Yograj Guggul

Yograj guggul are herbal tablets formulated by planet ayurveda using ingredients like- Guggul (Commiphora mukul), Amalaki (Emblica officinalis),Cardamomum (Elettaria cardamomum), Rasna (Pluchea lanceolata), Chitraka (Plumbago zeylanica) and many more. It is a useful preparation used in the treatment of splenomegaly, abdominal tumours, bone marrow, and increases digestion power. Yograj guggul is widely used in treatment of rheumatoid arthritis and gout.

Dosage– 2tablets twice daily with lukewarm water.

4. Ashwagandha Capsules

These are single herbals capsules formulated by planet ayurveda using standardised extract of Ashwagandha (Withania somnifera). Ashwagandha has rejuvenating that helps to maintain proper nourishment of the tissues. These capsules are useful in back stiffness, muscle fatigue, and have the property of balancing vata dosha in the body as vata dosha governs all the movement in the body. Ashwagandha has antioxidant, immunting enhancing, anti stress, rejuvenating properties. It inhibits inflammation and improves memory.

Dosage– 1 capsule twice daily with plain water after meals.

5. Nourish Maxx

Nourish maxx is a herbal powder preparation formulated by planet ayurveda using various ingredients like- Shatavari (Asparagus racemosus), Ashwagandha (Withania somnifera), Gokshura (Tribulus terrestris), Safed musli (Chlorophytum borivilianum). It helps to nourish the entire body, useful for both males and females, natural protein supplement for weight gain, bodybuilder, short height. Helps to maintain proper functioning of the organs. This powder has ashwagandha which helps to maintain and help the body to adapt to various types of stress.

Dosage– 1 tsp twice daily with normal water.

6. Brahmi Capsule

Brahmi capsules are single herbal preparation which is formulated by planet ayurveda using standardised extract of Brahmi (Bacopa monnieri). Brahmi is the best brain tonic which wonderfully works on brain health, promotes the regeneration of cells of the brain , so very helpful in Progessive supranuclear palsy, Alzheimer’s disease. It shows a miraculous effect on the liver as it removes the toxins from the body and promotes the functioning of the liver. Brahmi is useful in irregular menstruation, impotence, premature ejaculations, helps to relieve and prevent stress.

Dosage– 1 capsule twice daily with plain water.

CONCLUSION

Progessive supranuclear palsy is a uncommon brain disorder that causes difficulty in walking, eye movement, and balance.  The cause of this disease is unknown but there is accumulation of a protein called Tau within the brain.Vata dosha is responsible for control of all the nervous functions in the body. Further we studied its purva roop and many herbal remedies to cure this vata vyadhi. Planet Ayurveda also prepared many formulations which are useful in this disease without any side effects and maintained a healthy lifestyle for future needs. 

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September 13, 2022

Ayurvedic Prescpective Of Hereditary Motor Sensory Neuropathy(HMSN)

ABSTRACT

Hereditary motor sensory neuropathy commonly known as charcot marie tooth disease – is an inherited as well as progressive disorder. This condition is associated with the nervous system, the nervous system is the controlling center of the all body commands. It controls all the movements of the body and controls all processes of the body such as digestion, puberty, breathing and all other body processes. All the activities we perform, anything we feel, we say, all these are under the control of the nervous system. So if the nervous system is working properly then your whole body is healthy. But there are several conditions that are associated with the nervous system, among which one is HMSN disease, which is an inherited nervous disorder we are going to discuss in this article.

INTRODUCTION

Hereditary motor sensory neuropathy is an inherited nervous disorder that is also called as Charcot marie tooth disease. This disease is progressive in nature in which nerve cell deterioration is the main pathology. This concern is majorly seen in the legs and less commonly in the arms. The muscles of feet and hands get weak as the impulses towards these muscles are hampered. In addition to this there are a lot of symptoms to be faced that we will discuss further, so before studying the symptoms of HMSN let’s discuss the causes of HMSN.

CAUSES

There is no certain cause of HMSN, this disease is inherited. Chromosomes 1 and 17 seem to be affected chromosomes with mutation. It is inherited in autosomal recessive, autosomal dominant and the x-linked manner. Beside this there are some risk factors of HMSN such as Americans worldwide and in the generations children are more affected.       

Hereditary Motor Sensory Neuropathy

SYMPTOMS

The symptoms of HMSN can vary from person to person and it’s not possible to predict the age at which symptoms may appear. There are some early symptoms, main symptoms and later symptoms of HMSN, let’s discuss further.

Early symptoms of HMSN

In the early stages it is difficult to mark symptoms, they are usually evaluated when it gets worsened. Following are some symptoms that are noticed in the early stages:

  • Uncoordinated
  • Face difficulty while walking as the affected one may face problems with raising their feet up from the ground.
  • There is a kind of foot drop noticed, while lifting their feet the toes drops forward.

Main symptoms of HMSN

The main symptoms of HMSN are seen in the middle of 5-15 and the symptoms are not developed clearly until an affected one may lead to the middle or later ages. So below are the main symptoms of HMSN

  • Weakness of muscles in the legs, feet and ankles.
  • Feet are highly arched that leads to unstable ankle
  • Hammer toes (curled toes)
  • Lack of sensation in the feet and lesser than that in arms.
  • Poor blood circulation leads to cold hands and feet.
  • There is a wasting of muscles occurring in the lower legs that can lead to bottle shaped legs.

There are some additional symptoms that are noticed in some persons

  • Tremor (uncontrolled shaking)
  • Scoliosis (abnormal curvature of spine)
  • Dysphagia (problem while swallowing)
  • Difficulty while speaking
  • Difficulty breathing

Later symptoms of HMSN

As the HMSN proceeds to the later stages the weakness in the muscles and the sensation loss get worsened  that can start to affect the hands and arms the most. There is difficulty in performing even small tasks such as buttoning the shirt and performing day to day activities such as bathing, walking, sitting, etc. When they walk it puts strain on the muscles that further lead to joint and muscle pain. With growing age the mobility gets worse and a person may need an aid for walking.

DIAGNOSIS

The diagnosis of HMSN is done with the motor nerve conduction test and EMGs. A person to be diagnosed with HMSN should undergo a complete diagnostic and a clinical evaluation. The clinical diagnosis is done for the muscle weakness, atrophy and all types of sensory responses. For more clear diagnosis a blood DNA test is to be done.

AYURVEDIC VIEW OF HMSN

As we read earlier the HMSN is an inherited disorder, so as per ayurveda it is correlated with beeja dosha, which means the condition occurs with the defect in beejbhaga (sperm and ovum). Ashudh shukra and Ashudh artava (defected sperm and defected ovum) are considered as  the main causes of this condition. If there is any defect in the gametes (sperm and ovum) of parents then the child should inherit the disease. Beeja dosha due to the fact that if the mother conceived when her uterus or artava (gamete) is not totally vitiated but troubled by imbalanced doshas because of her improper diet intake. If there is any defect due to beej bhaga then cause beeja dosha and the deformity will occur in the fetus. As it is an inherited disease, we may manage the symptoms of the disease and there are some natural herbs that manage the symptoms of the disease and make the affected person’s life better by improving the quality of life.

HERBAL REMEDIES BY PLANET AYURVEDA FOR MANAGING HMSN

Planet Ayurveda is a GMP certified clinic which provides treatment for a wide range of diseases. All their remedies are formed under the guidance and supervision of M.D. ayurveda doctors and 100% purely vegetarian. Also while formulating their remedies they take care that any kind of added synthetic material should not be added to it like any sort of resins, fibre, colour, preservatives and all. For managing HMSN Planet Ayurveda listed 7 herbal remedies. Further we are going to discuss all about these herbal remedies and how it benefits the HMSN patients.

  1. ASHWAGANDHAGHAN VATI
  2. ATIRASADI CHURNA
  3. KUMARI SAAR
  4. TRIBULUS POWER
  5. MUSLI STRENGTH CAPSULES
  6. VRIHAT VATCHINTAMANI RAS
  7. NEUROGENIE CAPSULES

Ayurvedic Treatment For Hereditary Motor Sensory Neuropathy

Herbal Remedies for Hereditary Motor Sensory Neuropathy

PRODUCT DESCRIPTION

1. ASHWAGANDHAGHAN VATI

Ashwagandhaghan vati by Planet Ayurveda is a herbal remedy in tablet form which consists of a single herb Ashwagandha (Withania somnifera). As we discussed earlier the HMSN is an inherited disease so we can focus on managing the symptoms of the person and making the day to day life more ebay. So mainly the vata dosha is responsible for maintaining the neurological symptoms. Ashwagandha ghan vati helps in balancing vata dosha this helps in maintaining the symptoms of the HMSN.

Dosage: 2 tablets twice daily after meals with plain water.

2. ATIRASADI CHURNA

Atirasadi churna is the herbal remedy in powder form prepared by Planet Ayurveda. It consists of various balya (strengthening) herbs such as safed musli (Chlorophytum borivilianum), kali musli (Curculigo orchioides), gokshura (tribulus terrestris), shatavari (Asparagus racemosus), ashwagandha (Withania somnifera) and various others. This herbal remedy boosts up the overall strength of the affected person and helps in preventing muscle wasting, muscle strain, pain in the muscles and nerves, etc. Thus makes it easier to perform day to day activities.

Dosage: 1 tsp twice daily after meals with warm milk.      

3. KUMARI SAAR

Kumari saar is a herbal juice preparation formed by Planet Ayurveda with the help of juice extract of kumari (Aloe barbadensis) leaves. As we know the patients affected with HMSN need a perfect rejuvenation for leading a good quality life. This herbal remedy helps in providing that rejuvenating property to the patient and helps in boosting the immunity which makes the quality of life improved in the patient of HMSN.

Dosage: 2 tsp twice daily with plain water after meals.

4. TRIBULUS POWER

Tribulus power is a herbal remedy in capsule form that is formulated by Planet Ayurveda under the strict guidance of M.D. Ayurveda doctors. These capsules consist of pure herbal extract of gokshura (Tribulus terrestris) which contains various properties such as immunity-boosting and rejuvenating. So both these properties help in assisting the management of HMSN symptoms.

Dosage: 1 capsule twice daily with plain water after meals.

5. MUSLI STRENGTH CAPSULES

Musli strength capsules are available in capsules form and consist of standardized extracts of  safed musli (Chlorophytum borivilianum)  and gokshura (Tribulus terrestris). Safed musli is known for the rasayana (rejuvenates cells) and bruhmana (nourishing) properties. Gokshura consists of madhura rasa (sweet taste) which is  also nourishing in nature.   Both these herbs are very best in providing strength to the muscles and hence prevents the progressive muscle wasting in HMSN.

Dosage: 1 capsule twice daily with plain water after meals.

6. VRIHAT VATCHINTAMANI RAS

Vrihat vatchintamani ras is a classical ayurvedic formulation in tablet form. This is a herbo-mineral remedy which is prepared by Planet Ayurveda as per the method of preparation available in the classical texts. It consists of ingredients such as swarna bhasma (calyx of gold), rajat bhasma (calyx of silver), abhrak bhasma (calyx of mica) and various others. All the ingredients present in this ayurvedic formulation consists of miraculous vata balancing effects as the name suggests along with that it is balya in nature (strengthening) which provides strength to the muscles and nerves that alleviates the symptoms of HMSN.

Dosage: 1 tablet twice daily with plain water after meals.

7. NEUROGENIE CAPSULES

Neurogenie capsules by Planet Ayurveda consist of the standardized extract of Brahmi (Bacopa monnieri) and Ashwagandha (Withania somnifera). Brahmi (Bacopa monnieri) consists of antioxidant properties that aids in preventing the degeneration of the nerve cells thus restricting the further progress of the disease HMSN. Ashwagandha (Withania somnifera) contains wonderful rejuvenating and strengthening properties that help in managing the symptoms of HMSN such as muscle pain, difficulty in breathing, difficulty in lack of sensation, difficulty while walking, etc.

Dosage: 1 capsule twice daily with plain water after meals.

Contact Planet Ayurveda to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214040 Or Check Website – www.PlanetAyurveda.com

CONCLUSION

HMSN is an inherited disorder that is also called as Charcot marie tooth disease which is progressive in nature that includes nerve cell deterioration as the main pathology. . It occurs by the mutation (change) in the Chromosomes 1 and 17. In general the condition occurs due to transfer of defective genes from both the parents. According to Ayurveda HMSN is correlated to beeja dosha, which means the condition occurs with the defect in beejbhaga (sperm and ovum). Progressive muscle wasting, Severe disability, Disturbed gait, Decreased stability, Frequent falls, Difficulty in climbing stairs, Difficulty in walking, in short a person is unable to perform day to day activities. So if you are facing these issues, you must choose ayurveda treatment. It will improve your quality of life and make you better to perform day to day activities. For this purpose Planet Ayurveda is there for you with a miraculous list of herbal remedies, then stop worrying and start taking Ayurvedic medicine to improve your day to day life.

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