Herbal Remedies for PML Virus(Progressive multifocal leukoencephalopathy)

ABSTRACT

Brain is the center of command for the Nervous System which enables memory, thoughts, emotions and movement by a complex function, the highest consequence of biological evolution. As Brain controls each and everything happening in our body, it is necessary to maintain a healthy Brain throughout one’s life which is the ultimate goal in chasing health and longevity. As the community ages, the load of neurological disorders and provocations for Prevention of Brain Health increases. So as the Brain plays an important role in our life it is vital to understand why the Brain health is important. In today’s article we are going to discuss one such condition that affects the Brain health, PML (Progressive Multifocal Leukoencephalopathy).So let’s have a look!!!!

INTRODUCTION

PML means Progressive Multifocal Leukoencephalopathy, one of the diseases of CNS (Central Nervous System). In this condition a virus attacks the cells that are responsible for making myelin. Myelin is the coating that protects the nerve fibers of the Brain. PML can affect any part of the body, occurs rarely but is a life threatening condition. In Europe and the United States combined each year a total 4000 people suffer from PML. This condition gets worse over time passage and leads to serious complications. Further let’s discuss its causes, risk factors, symptoms and Ayurvedic View. So let’s have a look!!!!!

FACTS ABOUT PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY

Following are some facts that one must know about PML before discussing this condition in detail

• It is a condition which affects Brain and is caused by a virus.
• The condition is rare but progressive.
• Mainly DMARDs and Multiple Sclerosis increase its risk factor of development.
• As per Ayurveda this condition is correlated to Agantuk Janya Vata Vyadhi.
• The main thing to get rid of this condition or to prevent this condition is enhancing the immunity.

CAUSES AND PATHOPHYSIOLOGY OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY

PML is mainly caused by a viral infection named as JC Virus (John Cunningham Virus). PML is rare but this viral infection is common that is upto 85% of the adults can have this infection. JC virus can adapt at any age, at any time of the life but commonly affects in the childhood. This Virus mainly lodged in the lymph nodes, kidneys or bone marrow throughout our lifetime. Only a few people with JC Virus can get PML. If someone has JC Virus and the immune system gets severely compromised only then there is a chance of developing PML. so it is a must to take care of your immunity once you get to know about the JC Virus. If once it gets reactivated, reaches to the Brain, multiplies and starts to attack myelin. After the damage of myelin sheath a scar tissue starts forming, known as demyelination. It leads to the lesions that result from the interference of electrical impulses that travel from the Brain to other body parts, which leads to a variety of symptoms in different body parts.

RISK OF DEVELOPING PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY

PML occurs rarely if you have a healthy and boosted immune system. This condition only develops when the immune system gets compromised. Following are some other risk factors of developing PML:

• HIV-AIDS
• Leukaemia
• Lymphoma
• Hodgkin’s disease
• Various cancerous conditions
• Long term consumption of immunosuppressive therapy and corticosteroids
• Autoimmune conditions such as Rheumatoid Arthritis, Multiple Sclerosis, Systemic Lupus Erythematosus, Crohn’s Disease, etc.
• It can be caused by a side effect of various drugs such as – Dimethyl Fumarate, Natalizumab, Fingolimod, etc.

SYMPTOMS OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY

As long as the John Cunningham Virus remains inactive, one must not be aware about it. Once the virus gets activated PML causes great damage to the myelin which makes it hard for the Brain to send proper messages to other body parts. Symptoms of PML depends upon where the lesions are formed and the severity depends upto which extent the damage is caused. Initially the symptoms resemble the symptoms of pre-existing conditions like multiple sclerosis or HIV – AIDS. the symptoms of PML are as follows:

• Clumsiness issues
• General weakness
• Sensory loss
• Changes to vision
• Facial drooping
• Difficulty using legs and arms
• Loss of language skills
• Personality changes
• Mental slowness
• Memory problems

As the time passes these symptoms lead to various complications such as seizures, dementia, coma, etc. and PML will become a serious and life-threatening medical emergency.

DIAGNOSIS OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY

The physician may access PML based on progressive journey of symptoms, pre existing conditions and the medications one is  taking. The diagnostic test that may confirm PML includes the below techniques:

• Blood tests: Detects the high levels of antibodies.
• Lumbar Puncture: This sample also consists of antibodies if you have PML.
• Brain biopsy: It detects the lesion forming in the myelin sheath.
• Imaging tests: CT Scan or MRI detect the lesions occurring in the white matter of the Brain.

AYURVEDIC VIEW OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY

Ayurveda is a holistic science serving mankind for more than 3000 years. This science is working with the aim of maintaining the health of the healthy person and to alleviate the health concern of the diseased person. As we read earlier this condition affects the Brain and comes under Neurological conditions which are considered as Vata Vyadhi. Also the cause of this condition is JC virus which can be taken as Agantuk karana. So PML as per Ayurveda is a Vataj Vyadhi caused by Agantuk karana.

Vata Dosha is one among the three Doshas and it acts as a primary force beyond all body activities. Even it controls the activities of pitta and kapha dosha as well. If Vata dosha gets disturbed then all the body events will get disturbed and leads to many diseases known as Vata Vyadhi or neurological disorders.

According to Madhava Nidaan diseases caused by Vata dosha are known as Vata Vyadhi.

Common Causative factors of Vata Vyadhi

• Dry food, cold food, food intake in less amount, foods that are light to digest, awakening at night for a long time, excessive bleeding, depletion of tissues, trauma, injury to vital points.

Pathogenesis of Vata Vyadhi:

देहे स्त्रोतांसि रिक्तानि पूरयित्वा अनिलो बली।

करोति विविधान्‌ व्याधीन्‌ सर्व अङ्ग एक अङ्ग संश्रयान्‌।। (च. चि २८).

In this shloka this is explained that vata dosha get aggravated due to the above mentioned causative factors and get situated in rikta sthana (susceptible or empty channels), producing various vataj disorders. PML is also one of the Vata Vyadhi which is caused by Agantuk karana as we discussed earlier. Now we are going to discuss the Herbal Remedies by Planet Ayurveda that helps in managing the condition of PML.

HERBAL REMEDIES BY PLANET AYURVEDA FOR PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY

Ayurveda is a Holistic science serving mankind from more than 3000 years to maintain a healthy living. The aim of Ayurveda is to maintain the health of the healthy person and to alleviate any of the health issues. Planet Ayurveda is a company which has been working for 20 years on this aim. They produce various remedies that include herbal and herbomineral ingredients. These products are free from any kind of added preservatives, colours, fillers, etc. So the quality of products are well maintained and that’s why they have no kind of side effects. For helping a patient with PML Planet Ayurveda provides a PML Care Pack. Let’s discuss this pack with the ingredients of herbal remedies and how it helps in the management of PML. So let’s have a look!!!!

PML CARE PACK

1. SHILAJIT CAPSULES
2. BOSWELLIA CURCUMIN
3. MUSLI STRENGTH CAPSULES
4. GILOY CAPSULES
5. MEMORY SUPPORT
6. VRIHAT VATCHINTAMANI RAS
7. NEURO PLAN SYRUP
8. ENERGO PLAN SYRUP

PRODUCT DESCRIPTION

1. SHILAJIT CAPSULES

Shilajit Capsules is one of the single herbal capsule formulations of Planet Ayurveda. These capsules consist of standardised extract of Shilajit (Asphaltum). This is a wonderful formulation which assists in counteracting the free radicals, further preventing the degenerative diseases. It has miraculous adaptogenic properties which increase the action of other herbal remedies used to manage the condition. Other than that it has energy boosting properties which helps in alleviating weakness in case of PML.

Dosage: 1 capsule twice daily with plain water after meals

2. BOSWELLIA CURCUMIN

Boswellia Curcumin is a miraculous capsule formulation prepared by Planet Ayurveda. These capsules show wonderful effect as it includes standardised extract of herbs shallaki (Boswellia serrata) and Haridra (Curcuma longa). These capsules consist of properties like antioxidant and rejuvenating properties. The formulation helps in eliminating free radicals from the body and prevents degeneration due to JC Virus.

Dosage2 capsules twice daily with plain water after meals.

3. MUSLI STRENGTH CAPSULES

Musli strength capsules is a herbal capsules which is formulated by Planet Ayurveda under the category of polyherbal capsules. These capsules are prepared by standardized extract of herbs safed musli (Chlorophytum borivilianum) and Gokshura (Tribulus terrestris). The remedy consists of strengthening properties and immunity boosting properties. So these properties provide strength to the body, eliminate weakness and enhance immunity to reduce the impact of JC virus on the body.

Dosage: 2 capsules twice daily with plain water after meals.

4. GILOY CAPSULES

Giloy Capsules prepared by Planet Ayurveda with the standardized extract herb Giloy (Tinospora cordifolia). Giloy is an immunomodulatory, anti-inflammatory and antioxidant herb. It effectively boosts the immunity and assists in reducing virus effect in the body thus reducing the symptoms of PML Virus. The immunomodulatory effect of these capsules helps in preventing further impact of the JC virus.

Dosage:– 2 capsules twice daily with plain water after meals.

5. MEMORY SUPPORT

Memory Support is a capsule formulation one among all the polyherbal capsule formulation by Planet Ayurveda. These capsules consist of standardized extract of herb Vacha (Acorus calamus), Shankhpushpi (Convolvulus pluricaulis), Brahmi (Bacopa monnieri) and mulethi (Glycyrrhiza Glabra). All these herbs collectively assist in reducing stress, boosting memory power, and alleviates sensory loss as well. These herbal capsules effectively reduce the damage of the nervous system from JC virus by its antioxidant properties.

Dosage: 1 capsule twice daily with plain water after meals.

6. VRIHAT VATCHINTAMANI RAS

Vrihat Vatchintamani Ras is one of the classical Ayurvedic formulations that has been used since ancient times as an Ayurvedic rejuvenator. This formulation is available in tablet form and consists of various ingredients such as Swarna bhasma (Calyx of gold), loha bhasma (Calyx of iron), rajata bhasma (Calyx of Silver), etc. this formulation consists of rejuvenating and antioxidant properties, thus it is effective in preventing further degeneration of the myelin sheath by the impact of the JC Virus.

Dosage: 1 tablet twice daily with plain water after meals.

7. NEURO PLAN SYRUP

Neuro Plan Syrup is a polyherbal syrup formulation prepared by Planet Ayurveda. This syrup is made up of juice extract of herbs like Brahmi (Bacopa monnieri), Ashwagandha (Withania somnifera), pippali (Piper longum) and various others. All the herbs consist of properties like antioxidant, nervine, memory boosting and supports all the functions of the nervous system. Thus this syrup is supportive in managing the condition of PML.

Dosage: 2 tsp twice daily with plain water after meals

8. ENERGO PLAN SYRUP

Energo Plan Syrup by Planet Ayurveda is one of the herbal syrups. As the name suggests this syrup is especially formulated for boosting the energy. This syrup is made up of the juice of herbs like Amalaki (Emblica officinalis), Ashwagandha (Withania somnifera), Gokshura (Tribulus terrestris), Shigru (Moringa oleifera) and various others. All these herbs consist of strengthening and rejuvenating properties, thus assisting in alleviating various symptoms like Weakness, difficulty walking, difficulty doing daily activities, etc.

Dosage:2 tsp twice daily with plain water after meals.

Contact Planet Ayurveda Support Team to provide you the costing/ordering and delivery information at – costing.planetayurveda@gmail.com or Call at 0172-521-4040 (India), +91-172-521-4040 (Outside India) or Whatsapp at (+91) 842-749-4030.

CONCLUSION

PML means Progressive Multifocal Leukoencephalopathy, one of the diseases of CNS (Central Nervous System). In this condition a virus attacks the cells that are responsible for making myelin. PML is mainly caused by a viral infection named as JC Virus (John Cunningham Virus). Symptoms vary in every individual but some common symptoms involve Clumsiness issues, General weakness, Sensory loss, Changes to vision, Facial drooping, Difficulty using legs and arms, Loss of language skills and some others. Diagnosis of this condition can only be cleared by Blood tests, lumbar puncture, brain biopsy and certain imaging tests such as CT Scan MRI, etc. As per Ayurveda this condition can be correlated to Agantuj Vata Vyadhi and its management can be done as per the management of the Vata Dosha vitiation. For this Planet Ayurveda provides various remedies that are free from any kind of side effects, so you can consume these remedies for managing your condition of PML