Pyoderma Gangrenosum : Causes, Risk Factors, Diagnosis & Treatment


Pyoderma gangrenosum is an autoimmune disorder. Autoimmune disorders are disorders that occur when our immune system mistakenly attacks its own body. When the immune system produces antibodies they attack the cells of its own body then the condition is known as an autoimmune disorder. There are many types of autoimmune disorders such as Ulcerative colitis, celiac disease, lupus, grave’s diseases, etc.  The immune system normally guards the body against various germs like viruses and bacteria. When this system senses the foreign particles then it sends out an army to attack them. But in autoimmune disorders, our immune system releases the antibodies that attack the healthy part of the body such as joints, skin, intestines etc. So in this article, we are going to discuss one of the autoimmune disorders that are Pyoderma gangrenosum, and its Ayurvedic management.


Pyoderma gangrenosum is a rare condition of the skin in which large, painful sores develop on the skin. These skin ulcers mostly occur on the legs. These ulcers can develop quickly and clear up with treatment but recurrence is common in autoimmune diseases. In Pyoderma gangrenosum, there is an inflammation of the skin with painful pustules or nodules which further becomes ulcers and ulcers progressively grow. This disease is not infectious. This in fact is a serious ulcerating skin disease with deep ulceration with a well-defined border.
pyoderma gangrenosum


The exact cause for this disease is not known. But the researchers believe that it is associated with autoimmune diseases such as ulcerative colitis, Crohn’s disease, Arthritis, etc.

Clinical Features

It usually starts with a small, red bump over the skin. This may resemble a spider bite and after a few days this bump can develop into painful and large sores. It may develop anywhere on the body but commonly develop on the legs.

Risk Factors

These certain factors may increase the risk of developing this disease:

  • Inflammatory bowel disease
  • Having arthritis
  • Blood disorders
  • Age and sex


This disease will be diagnosed with a proper medical history and a physical examination. There is no specific test for Pyoderma gangrenosum disease. But the doctor will suggest you some blood tests to rule out the cause of this disease. Doctor will also suggest a skin biopsy.


The treatment aim is to reduce inflammation, pain and promote wound healing. The drugs of choice are corticosteroids and ciclosporin. For topical application some ointments are used such as Clobestol, mupirocin and gentamicin can be effective. This treatment protocol gives symptomatic relief and if treated then recurrence is common.

Ayurvedic Treatment

As we all know that there is no permanent solution for Autoimmune disorders in Allopathic medicine. But don’t worry Ayurveda has an answer for autoimmune diseases. In ancient times science treated these disorders from their root cause. We have wonderful herbal remedies for treating this rare skin disease.

Herbal Remedies For Pyoderma Gangrenosum

  1. Gandhak Rasayan
  2. Pitta balance
  3. Manjishtha Capsules
  4. Neem Capsules

Products Description

1. Gandhak Rasayan

This is a classical formulation in Ayurveda. It is used in treating various skin diseases. It is an Ayurvedic mineral-based medicine that is formed with detoxified gandhak (Sulphur) which is processed with herbal juices. It has antibacterial, antiviral properties. It also improves the immune system and eliminates impurities out from the body. It is an excellent remedy for boils, urticaria, eczema, acne, etc.

Dosage : 2 tablets twice a day with plain water after meals

2. Pitta Balance

This polyherbal formulation is an effective remedy for digestive ailments. It balances the pitta dosha and also balances the heating feeling in the body. Too much consumption of oily foods, spices can lead to an imbalance of pitta dosha and causes various metabolic disorders. This will also lead to autoimmune diseases. So the ingredients in this formulation such as Praval pishti (Coral compound), Akik pishti (Agate compound), Kamdudha ras (compound), etc. helps in treating this inflammatory skin disease by improving the digestive system.

Dosage : 1 capsule twice a day with plain water after meals

3. Manjishtha Capsules

This is a single herbal capsule. These are very useful for skin problems. This is prepared from the standardized extracts of Manjishtha (Rubia cordifolia). As this disease is an inflammatory skin disease so this remedy is very helpful in managing this disease. It has blood purifying properties. It heals bruises and relieves pains and swelling. It enhances blood circulation and detoxifies the body. These capsules are rich in antioxidants and support a healthy immune system.

Dosage : 1 capsule twice a day with plain water after meals

4. Neem Capsules

This is an Ayurvedic herbal remedy that is an effective herbal supplement for skin problems. It is made with the standardized extracts of Neem (Azadirachta indica). It is nature’s best blood purifier and is a very effective remedy for urticaria, eczema, boils, and other skin problems. It relieves the irritation and pain which is a symptom of this Pyoderma gangrenosum. Neem has anti-bacterial, antifungal, and antiparasitic properties.

Dosage : 2 capsules twice a day with plain water after meals

Contact Planet Ayurveda Support Team to provide you the costing/ordering and delivery information at – or Call at 0172-521-4030 (India), +91-172-521-4030 (Outside India) or Whatsapp at (+91) 9915-593-604


Therefore coming to an end we can say the above provided herbal formulations are safe and manage this condition very well. As we discussed above, it most often occurs in patients with autoimmune disorders so we should focus a bit more on our diet and lifestyle. If our diet should be healthy then our immunity will be on a higher side. So use these formulations and for further queries you can contact us on

Dr. Vikram Chauhan

Dr. Vikram Chauhan (MD - Ayurveda) is a Globally Renowned Ayurveda Physician with Expertise of more than 25 Years. He is the CEO & Founder of, a leading Ayurveda Brand, Manufacturing, and Export Company with a Chain of Clinics and Branches in the US, Europe, Africa, Southeast Asia, India, and other parts of the World. He is also an Ayurveda Author who has written Books on Ayurveda, translated into Many European Languages. One of his Books is "Ayurveda – God’s Manual for Healing". He is on a Mission to Spread Ayurveda All Over the Planet through all the Possible Mediums. With his Vast Experience in Herbs and their Applied Uses, he is successfully treating Numerous Patients suffering from Various Ailments with the help of the Purest Herbal Supplements, Diet, and Lifestyle, according to the Principles of Ayurveda. For More Details, visit -,

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