Tag: Ayurveda for Granulomatous Meningoencephalitis

Granulomatous Meningoencephalitis (GME) And Its Ayurvedic Treatment

Abstract

The central nervous system is mainly associated with the brain and spinal cord. Meninges are the three-layered covers of CNS. These layers of meninges are meant to protect the brain and spinal cord. The brain is called an encephalic. Inflammation involves normal tissue infiltration by immune system cells. Cells of the immune system release biochemicals in the area of infectious organisms. Thus we have to discuss the inflammation of the brain and meninges which in collaboration is called meningoencephalitis. Let’s read!!

Granulomatous Meningoencephalitis (GME)

Introduction 

GME is an inflammatory disease in dogs associated with the central nervous system and characterized by granulomatous lesions which may be focal or disseminated in the brain or spinal cord. GME was first noted in dogs in 1978. GME is of three types focal, multifocal, and ocular. Ocular type of GME is not common, and sudden onset of optic neuritis and thus blindness is the peculiar feature of Ocular meningoencephalitis. In focal and multifocal (disseminated) forms the lesions are spread throughout the central nervous system. Focal lesions are generally seen and are more common in the cerebrum and brainstem. GME is more common in female dogs of middle age. Thus in this article, we will read about GME and its Ayurvedic aspect.

Signs and symptoms  

Below are the signs and symptoms associated with GME.

1. Seizures

2. Unable to recognize the owner

3. Depression

4. Disorientation

5. Coma

6. Hyperventilation

7. Abnormal appetite

8. Disturbed temperature regulation

9. Hormonal disturbances

10. Tremors.

11. Pain

Causes

The GME is idiopathic in origin and thus the precise causes are unknown as per modern studies. Though the role of the immune system is questionable or immune-mediated causes can be there. Ayurvedic causes

Diagnosis

Biopsy of brain tissue is the basic requirement for the brain tissue. Brain biopsy is a difficult task. This GME can be found after proper analysis of the clinical features of dogs and related history.

Ayurvedic Aspect 

The pashu chikitsa is a well-known approach for the management of our pets. Ayurvedic pashu chikitsa is a result of the knowledge and intellect of our ancient saints and sages. It shows a great companionship between humans and animals. GME in Ayurveda can be associated with vatavyadhi and ama dosha. The chief underlying cause is the vitiation of vata associated with aamdosha leads to kaphaj granthi (Granuloma) in Majja dhatu (CNS). Vata dosha is concerned with activities and motility in the body. The associated aamdosha leads to vitiating the dosha and causes dhatu dushti and is the basic cause of inflammation in the body due to excessive accumulation of Endotoxins. For better body status all the doshas should be in a balanced state. A beautiful quote is mentioned in Sushruta Samhita–  

Susruta sutra sthana 15/41/…

Means – According to Acharya Susruta, a person is said to be swastha (Healthy) when doshas (Vata/pitta/kapha), agnis, dhatus, and mala should be in equilibrium along with mental, sensory, and spiritual calmness and happiness.
Ayurveda principles and herbs with minerals help to manage the status of GME in dogs. Herbs like Brahmi (Bacopa monnieri), Mandukaparni (Centella asiatica), Shankhpushpi (Convolvulus pluricaulis), Jyotishmati (Celastrus paniculatus), Ashwagandha (Withania somnifera) are helpful. Minerals like Swarna Bhasma (gold calx), Rajata Bhasma (silver calx), and Loha Bhasma (iron calx) are also beneficial. Herbal formulations of Planet Ayurveda are helpful for the management of GME.

Herbal remedy by Planet Ayurveda for the management of Granulomatous Meningoencephalitis in dogs

Planet Ayurveda is a GMP-certified manufacturing hub for the formulation of best-quality herbal remedies. The prime goal of Planet Ayurveda is to promote Ayurveda in each and every household in the world. In this thread, we are here to manage the issues associated with our beloved pets with herbal formulations based on the principles of Ayurveda mentioned in the Pashu chikitsa. Below is the herbal formulation for the management of Granulomatous meningoencephalitis.

Product List

1. Neuroplan Syrup

2. Brahmi Capsules

3. Ashwagandha capsules

4. Vrihat Vatchintamani Ras

Herbal Remedies For Granulomatous Meningoencephalitis (GME)

Herbal Remedies For Granulomatous Meningoencephalitis (GME)

Product Description

1. Neuroplan syrup

The Syrup Neuroplan is the herbal formulation of Planet Ayurveda contains Brahmi (Bacopa monnieri), Mandukaparni (Centella asiatica), Shankhpushpi (Convolvulus pluricaulis), Jyotishmati (Celastrus paniculatus), Ashwagandha Withania somnifera, Bhojpatra (Betula utilis). Neuroplan syrup is useful to manage the status of problems associated with the nervous system. It also helps to pacify the vata dosha and acts as a nervine tonic in the condition of Granulomatous meningoencephalitis. It is also helpful to manage the levels of cortisol in the body.

Dosage  10 ml twice daily with plain water after meals.

2. Brahmi Capsules

The Brahmi Capsule is the herbal formulation of Planet Ayurveda having Brahmi (Bacopa monnieri) as the chief ingredient. The Brahmi cap is able to drain out the stress in dogs associated with MMM. It helps to promote nerve conduction and is able to promote the brain tone as well. It is able to prevent brain damage and reduce stress and anxiety. Brahmi helps to promote strength and intellect as well.

Dosage  2 caps twice daily with plain water after meals.

3. Ashwagandha Capsules

The chief ingredient of the Ashwagandha capsule is the standardized extract of Ashwagandha (Withania somnifera). Ashwagandha is known to reduce inflammation and act as a pain reliever. The presence of Withanolides in ashwagandha helps to reduce inflammation. Also, ashwagandha acts as a powerful analgesic which is evident to soothe the nervous system and reduce pain as well. Ashwagandha helps to promote brain health and acts as an immunity modulator.

Dosage 1 cap daily with plain water after meals.

4. Vrihat Vatchintamani Ras

Vrihat Vatchintamani rasa is a classical herbomineral formulation of Planet Ayurveda. As the name indicates this rasa preparation is known to reduce the pain associated with vata dosha. The chief ingredients of this formulation are Swarna Bhasma (gold calx), Rajata Bhasma (silver calx), Abhrak Bhasma (calx of Mica), Loha Bhasma (calx of iron), Pravala Bhasma (calx of coral), Mukta Bhasma with aloe vera extract and many more. It helps to maintain healthy functioning of the brain, maintains a healthy nervous system, supports mental health, and supports healthy digestion.

Dosage  1 tab twice daily with plain water after meals.

CONTACT  PLANET AYURVEDA  TO PROVIDE YOU WITH THE    COSTING / ORDERING AND DELIVERY INFORMATION AT – COSTING.PLANETAYURVEDA@GMAIL.COM OR CALL AT +91-172-5214040

Conclusion

The Granulomatous is associated with the deprived status of the Central nervous system. It is a disease of concern for beloved pets, the dogs. It is a very painful condition associated with depression, disorientation, coma, inability to recognize the owner, abnormal appetite, hyperventilation, and disturbed temperature regulation. The herbal formulations by Planet Ayurveda are able to manage the status of GME and are able to prevent the side effects of synthetic medicines. As GME is associated with disease of the Central nervous system and is inflammatory with progressive nature. It is important to deal with the problem accordingly and immediate action is needed with herbal remedies thus avoiding the side effects of long-term use of synthetic medicines.        

Ayurvedic Aspects of Granulomatous Meningoencephalitis (Gme)

ABstract

Granulomatous meningoencephalitis is an idiopathic inflammatory central nervous system of dogs. It commonly shows neuropathic changes in dogs and cats. The central nervous system includes the spinal cord and the brain which controls the essential functions of life which include the cerebrum and cerebellum. Specialized tissues known as meninges cover the brain and spinal cord and have cerebrospinal fluid. The peripheral nervous system has nerves which coordinate the rest of the body. Neurons connect with each other and form the neurological unit which has 2 units known as dendrites and axons. It can be due to infections or immune-mediated causes and contains three layers which are dura (outer layer), arachnoid (internal thin meninge) and Pia mater (thin and highly vascular membrane). In this article, we are going to discuss the causes, symptoms and ayurvedic aspects of granulomatous meningoencephalitis in detail.

INTRODUCTION

Granulomatous meningoencephalomyelitis is an inflammatory condition of the central nervous system which is mainly characterized by focal lesions which are present in the brain and spinal cord. It was first reported by Braund and his colleagues in 1978. Commonly seen in female dogs of young and middle age. The focal lesions are mainly seen in the white matter of the cerebrum, brainstem and in cerebellum. It commonly involves the infiltration by mononuclear cells which destroys the debris. In granulomatous inflammation, there are cuffs which are around the blood vessels of the brain and spinal cord. In pug dog encephalitis it is an idiopathic inflammatory disease which usually affects the prosencephalon which is commonly known as necrotising meningoencephalitis. It only differs from GME in more breakdown of the tissues and increase in eosinophils. The cells of the immune system release destructive biochemicals which invade the organisms of the disease’s tissue.

Granulomatous meningoencephalitis in Dogs

TYPES

1. Disseminated

It is the diffuse type of disease present throughout the Central nervous system. It is also known as inflammatory reticulosis. Accumulation of mononuclear cells and neutrophils around the blood vessels in the form of meningitis which causes fever and neck pain.

2. Focal

It is present as granuloma which sometimes mimics tumors found in the cerebellopontine angle. It is a chronic progressive disease (3-6 months).

3. Ocular

It is the uncommon form of Granulomatous meningoencephalitis which shows sudden blindness which is due to neuritis. This retinal detachment and secondary glaucoma are seen in this type.

PATHOLOGY

In granulomatous meningoencephalitis, it occurs mainly within the white matter of the CNS (Central nervous system) which is characterized by dense inflammatory cells which are arranged in whorling patterns. There are varying numbers of Lymphocytes, monocytes and multinucleated giant cells which are mainly seen in the cerebrum, cerebellum and in the cervical spinal cord. These perivascular cuffs merge at blood vessels to form the whorls which form nodules which is due to the MHC class 2 and CD3+ T cells hypersensitivity reaction. Granulomatous lesions get compressed and get invaded in CND parenchyma which results in necrosis and oedema. The lesions are seen in the brain stem especially the pontomedullary region and white part. This lesion is usually detected by CT and MRI techniques.

PUG DOG ENCEPHALITIS

A pug dog is a beautiful family dog which is associated with a rare neurological disease which is mainly fatal. Encephalitis is the inflammation of the brain tissue which tends to strike at 2-3 years of age. It causes inflammation and death of the brain tissue. Affects small dog breeds including Maltese, Chihuahuas and Yorkshire terriers. It is usually an auto-immune inherited disease, an idiopathic inflammatory disease which usually affects the prosencephalon (forebrain and thalamus). Also known as necrotising meningoencephalitis. The prevalence of pug dog encephalitis is about 1 % which differs from granulomatous meningoencephalitis which leads to breakdown and increase in the number of white blood cells (eosinophils).

SYMPTOMS

  1. Disseminated-
  2. Fever
  3. Pain in the neck region
  4. Loss of balance
  5. Depression
  6. Seizures

1. Focal

It usually affects the discrete bone area which resembles a tumor. Various symptoms include are

  • Blindness
  • Progressive weakness
  • Loss of balance
  • Dementia
  • Neurological signs

2. Ocular

It usually causes retinal detachment and glaucoma

  • Affects the nerves which are supplied to the eyes.

DIAGNOSIS

  1. Cerebrospinal fluid Analysis (CSF)
  2. Brain biopsy
  3. CT Scan (Computed tomography)
  4. MRI (Magnetic resonance imaging)

TREATMENT

  1. Corticosteroid with immunosuppressive drugs.
  2. Cytosine arabinoside
  3. Radiation therapy
  4. Procarbazine
  5. Cyclosporine
  6. Surgical removal of the brain Granulomatous meningoencephalitis (GME) lesion.

AYURVEDIC ASPECT

Ayurveda is the oldest system of holistic medicine which means Science (ved) of life. Ayurveda in veterinary medicine has mainly focused on animal welfare, treatment therapies and management. In Rigveda, physicians described the treatment for both animals and humans and Salihotra was the first credited as an animal healer and wrote a book on veterinary medicine. Pandavas (Nakul and Sahadev as experts treated animals and the ayurvedic treatment for animals in modern science is known as Pashu Chikitsa. Pashu Chikitsa has been a vital part of Indian history and many animals are considered vehicles of dogs and goddesses, which shows the importance of animals.

Granulomatous meningoencephalitis is a dog’s condition which affects the nervous system and in ayurveda, it generally relates to inflammation which is due to vitiated pitta doshas, the vitiation of Kapha doshas (shows numbness as the primary symptom) along with Vata doshas. However, it shows the vitiation of tridoshas and the treatment will be advised to balance the imbalance doshas which is seen in dogs. Animals too have three primary types of Prakriti (Vata, Pitta and Kapha). Ayurveda has a history of extensive veterinary treatment systems which makes sense to discover from ancient texts and bring out the natural and side-effect-free treatment for our pets. The various medications which are useful for the management of Granulomatous meningoencephalitis are-

  1. Dashmoolarishta
  2. Triphala Churna
  3. Giloy ghan vati
  4. Brahmi Ghrita
  5. Shankhpushpi Churna

HERBAL REMEDIES BY PLANET AYURVEDA FOR GRANULOMATOUS MENINGOENCEPHALITIS

Planet Ayurveda is an emerging US-FDA-registered, GMP-certified ISO 9001:2015 registered ayurvedic company which formulates its own medications as described in the ancient ayurvedic texts books. These formulations are prepared without any preservatives which cause any harmful effect on the human body. Products which are manufactured are pure and devoid of any kind of adulteration. For granulomatous meningoencephalitis in dogs, planet ayurveda provides many herbal formulations which are causing no side effects and are useful for dogs.

PRODUCTS LIST

  1. NEURO PLAN SYRUP
  2. BRAHMI CAPSULES
  3. ASHWAGANDHA CAPSULE
  4. VRIHAT VATCHINTAMANI RAS

herbal supplements for Granulomatous meningoencephalitis

Herbal Remedies for Granulomatous Meningoencephalitis

PRODUCTS DESCRIPTION

1. Neuro Plan Syrup

Neuroplan Syrup is a herbal syrup which is formulated by planet ayurveda using ingredients such as Brahmi (Bacopa monnieri), Bhojpatra (Betula utilis), Sonth (Zingiber officinale) and many more. Neuro plan syrup is helpful in maintaining pressure and stress on the nervous system. Enhances the power of nerves and strengthens memory and promotes energy. Has a soothing effect and relieves any kind of inflammation in the central nervous system.

Dosage- 10 ml teaspoon twice daily.

2. Brahmi Capsules

Brahmi Capsules are single herbal capsules made by planet ayurveda using a standardized extract of Brahmi (Bacopa monnieri). These capsules are working as rejuvenating for the nervous system, used in ancient times as a brain tonic so known as a memory enhancer. Brahmi Capsule is a good supplement for the liver and is helpful in detoxifying it and enhancing the period of life.

Dosage– 2 capsules twice daily after meal with plain water.

3. Ashwagandha Capsules

Ashwagandha Capsules are single herbal capsules from planet ayurveda which contain standardized ingredients such as Ashwagandha (Withania somnifera). These capsules increase stress resistance and improve memory-related performances and perform the normal functioning of the nervous system. Provides calmness and mental satisfaction. Provides proper nourishment to the brain for proper functioning.

Dosage– 1 capsule twice daily after meal with plain water.

4. Vrihat Vatchintamani Ras

Vrihat Vatchintamani Ras is a classical ayurvedic product which is prepared by planet ayurveda using Swaran Bhasma (Calx of gold), Mukta Bhasma (Calx of pearl), Loha Bhasma (Calx of iron) and many more. These tablets are helpful in treating imbalanced Vata dosha and pitta doshas. Rich in antioxidants which act as a nerve tonic and strengthen the muscles of the heart. Has a cooling effect which reduces the aggravated heat from the body.

Dosage– 1 tablet twice daily after meal with plain water.

Contact Planet Ayurveda to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214040 Or Check Website – www.PlanetAyurveda.com

CONCLUSION

Granulomatous meningoencephalitis is an idiopathic inflammatory central nervous system of dogs. It commonly shows neuropathic changes in dogs and cats. Commonly seen in female dogs of young and middle age. The focal lesions are mainly seen in the white matter of the cerebrum, brainstem and in cerebellum. And the ayurvedic treatment for animals in modern science is known as Pashu Chikitsa. Pashu Chikitsa has been a vital part of Indian history and many animals are considered vehicles of dogs and goddesses, which shows the importance of animals. For the treatment of granulomatous meningoencephalitis planet ayurveda provided many herbal products which are useful in this without causing any side effects.