Tag: SSPE

Subacute Sclerosing Panencephalitis Treatment in Ayurveda

Abstract

When a neurological disorder caused by inflammation of the brain (encephalitis) is known as Subacute sclerosing panencephalitis (SSPE). This disease can be caused by the reactivation of the measles virus or by inappropriate immunity to the measles virus. SSPE usually occurs 2 to 10 years after the initial infection. Initial symptoms may include memory loss, loss of smell, seizures, muscle weakness and/or behavioural changes leading to dysfunction. In this article, we are going to discuss the causes, symptoms and treatment of Subacute sclerosing panencephalitis.

Subacute Sclerosing Panencephalitis

Introduction

Dawson’s disease is the other name for Subacute sclerosing panencephalitis (SSPE). It is a complication of the measles virus. It is a deadly brain disorder. It is a rare brain disease caused by measles. This condition usually affects children, adolescents and young adults.

Causes Of SSPE

An abnormal immune response to measles may cause severe brain damage. When measles spreads from person to person it develops both acute or chronic neurological complications like Subacute sclerosing panencephalitis (SSPE).

Pathogenesis Of SSPE

The pathogenesis of SSPE is unclear. But measles antigens have been found in the neurons and glial cells of patients with SSPE.

Symptoms Of SSPE

  • Hallucination
  • Insomnia
  • Inflammation in brain
  • Poor school performance
  • Motor function disturbed
  • Distract easily
  • Behaviour change
  • Intellectual problem
  • Memory loss
  • Irritability
  • Outburst of temper
  • Ataxia
  • Involuntary muscle movements
  • Blindness
  • Elevated body temperature
  • Abnormality of respiration
  • Abnormality of heartbeat
  • Abnormality of blood pressure

Diagnosis Of SSPE

  • Test of cerebrospinal fluid
  • Blood test to find out the level of antibody to the measles virus
  • EEG
  • MRI
  • CT
  • Biopsy of the brain

Treatment Of SSPE

At present, there is no treatment for subacute sclerosing panencephalitis (SSPE). Only supportive treatment is given for this disease.

Ayurvedic Aspect of Subacute Sclerosing Panencephalitis

In Ayurveda, we can correlate SSPE with two factors, one of the factors is agantuj vyadhi due to the fact it is a result of the measles virus and every other is vitiation of tridosha that is vata, pitta and kapha together with dushti of pranavaha srotas. Vitiation of vata takes the obstruction in the passage. Vata, pitta and kapha move in all of the channels of the body. This produces symptoms of all three doshas in this ailment.

Herbal Remedies for Subacute Sclerosing Panencephalitis by Planet Ayurveda

Planet ayurveda is a GMP – certified clinical and ISO 9001:2015 certified US FDA-registered company. In Planet Ayurveda, the formulation of various remedies from the holistic system of ayurveda to provide relief from disease is manufactured here. In Planet Ayurveda, formulations of herbal remedies are preservative-free. For the treatment of Subacute sclerosing panencephalitis (SSPE), Planet ayurveda provides various supplements without causing any side effects.

Product List

  1. Gandhak Rasayan
  2. Neurogenie Capsules
  3. Boswellia Curcumin
  4. Gotukola Capsules
  5. Indian Valeriana

Herbal Remedies for Subacute Sclerosing PanencephalitisBuy Now: Herbal Remedies for Subacute Sclerosing Panencephalitis

Product Description

1. Gandhak Rasayan

Gandhak rasayan is a single herbal tablet formulated by Planet Ayurveda by using shuddha gandhak (Purified sulphur). It is an immunity booster. It acts as an antibacterial, antimicrobial and anti-inflammatory herb. It pacifies all three doshas which are vata, pitta and kapha. It also purifies the blood. It is useful in urinary tract infections and removes harmful pathogens from the body. It increases body strength and boosts immunity.

Dosage- With plain water 2 tablets twice daily after meals.

2. Neurogenie Capsules

Neurogenie is a polyherbal capsule which is formulated by Planet Ayurveda by using Brahmi (Bacopa monnieri) and Ashwagandha (Withania somnifera). The taste of herbs is bitter and astringent, the effect is mild and slightly warm. It is a pacifier for all three Vata, Pitta and Kapha dosha. It has a tonic effect on the brain and nervous system. With its antioxidant properties, it can improve learning, improve memory and thinking. It is a medicine that allows the mind to retain information about work and intellectual pursuits. It is good for regulating all three energies and prevents the destruction of vata energy, which is the main thing that controls the nervous system. It is an excellent remedy for reducing the effects of stress and anxiety.

Dosage- With plain water, 2 capsules twice daily.

3. Boswellia Curcumin

Boswellia curcumin is a polyherbal capsule which is formulated by Planet Ayurveda by using Shallaki (Boswellia curcumin) and Haridra (Curcuma longa). The combination of Shallaki (Boswellia serrata) and Curcumin (Curcuma longa) helps reduce pain and give synergistic effects. In this shallaki it acts as an anti-inflammatory herb and curcumin acts as an antioxidant. It has antioxidant properties that protect brain neurons and reduce skin wrinkles. It is known as an antibacterial, antiallergic, carminative and diuretic drug. It is good for sprains, wounds and joints. It cleans the blood and helps blood production in the body. It is used to treat many conditions such as acne, blemishes, burns, autoimmune diseases and hepatitis. It prevents intestinal and skin diseases.

Dosage- With plain water, after meals 1 capsule twice daily.

4. Gotu Kola Capsules

It is a single herbal capsule which is formulated by Planet Ayurveda by using gotu kola (Centella asiatica). It acts as tranquillisers, anticonvulsant, muscle relaxant and blood purifier. It is light and mildly hot in effect. It is bitter and astringent in taste. It helps in enhancing the memory and learning power. It also reduces anxiety and depression. It helps with sleeplessness and mental retardation. It is effective in age-related mental disorders in old persons and also helps maintain clarity of thoughts. It is indicated in anxiety, depression and nervous exhaustion.

Dosage- With plain water, 2 Capsules twice daily after meals.

5. Indian Valeriana

It is a single herbal capsule which is formulated by Planet Ayurveda by using Tagar (Valeriana wallichii). It is bitter, pungent and astringent in taste. It is light, slimy and hot in effect. It is a wound healer. It balances all three doshas especially vata and kapha dosha. It is a soothing and sedative action on the central nervous system. It is very effective in restlessness, palpitations and mild hypertension. Due to its sedative action, it is very effective in chronic anxiety, depression, insomnia, migraine, and tension headaches. It is also indicated in convulsion, general debility and skin disease.

Dosage- With plain water, 1 capsule twice daily after meals.

Contact Planet Ayurveda Support Team to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or Call at 0172-521-4040 (India), +91-172-521-4040 (Outside India) or Whatsapp at (+91) 9915-593-604

Conclusion

Dawson’s disease is the other name for Subacute sclerosing panencephalitis (SSPE). It is a complication of the measles virus. It is a deadly brain disorder. It is a rare brain disease caused by measles. This condition usually affects children, adolescents and young adults. In Ayurveda, we can correlate SSPE with two factors, one of the factors is agantuj vyadhi due to the fact it is a result of the measles virus and every other is vitiation of tridosha that is vata, pitta and kapha together with dushti of pranavaha srotas. In Planet Ayurveda there are some herbal remedies which are formulated by ayurveda experts. These remedies give effective results in Subacute sclerosing panencephalitis (SSPE) without causing any side effects.

Herbal Treatment for SUBACUTE SCLEROSING PANENCEPHALITIS (SSPE)

Abstract

In 1933, Dawson described an entity he termed “inclusion body encephalitis,” which was characterized by subacute encephalitis, loss of nerve cells, and Cowdry A inclusion bodies in neurons and glial cells. Van Bogaert (1945) reported a clinically similar disease in which the white matter of the brain showed intense fibrillary gliosis associated with a variable subacute inflammatory infiltrate, which he called “subacute sclerosing leukoencephalitis”. Later, inclusion bodies were found in Van Bogaert’s cases. It is now clear that both authors were describing the same disease, and further, that the disease is related to infection by the measles virus. The disease is now designated as subacute sclerosing panencephalitis. So, today we will read about SSPE in this article in brief.

Subacute sclerosing panencephalitis

Introduction

It is a condition of progressive neurological-related disorder which affects mainly the central nervous system of the brain that leads to inflammation of the brain. The disease generally attacks children, although it can sometimes be seen in adolescents and young adults. The onset is heralded by personality changes, followed by involuntary movements.

Causes and Pathogenesis

It is caused by measles infection and disease diagnosed after many years of measles infection. The precise pathogenesis of SSPE is unclear, but several pieces of evidence suggest that lysis of neurons or oligodendroglia is induced not by direct action of the virus, but rather by antibody or cell mediated reactions directed against viral infected cells.

Symptoms

  • Poor school performance
  • Hallucination
  • Insomnia
  • Inflammation in brain
  • Distract easily
  • Motor function disturbed
  • Temper outburst
  • Suddenly muscular jerks of head, arms or other body part may occur
  • Behavioral changes
  • Intellectual problem
  • Forgetfulness
  • Ataxia
  • Later, muscle rigidity increase and difficulty in swallowing

Diagnosis

On gross examination

The brain may be normal or firm and may contain regions of granularity and focal destruction.

On microscopic examination

There is a perivascular mononuclear cell infiltrate as well as Cowdry A inclusion bodies in neurons or oligodendroglia. Such inclusions have been shown to contain viral particles by electron microscopy. Neuronophagia and extensive neuronal loss are present in severely involved regions. Dense fibrillary gliosis follows as the process becomes older.

EEG

The EEG exhibits characteristic bursts of high-voltage activity. In most cases, the disease progresses relentlessly and devastates the brain, often leading to death.

CSF (cerebrospinal fluid)

An elevation of IgG is present in CSF, with an oligoclonal pattern and high levels of measles antibodies are present in the CSF of such patients.

Fluorescent antibody test

Measles antigen has been found in the neurons and glial cells of patients with SSPE by the direct fluorescent antibody test

Brain biopsy

Measles virus has also been cultured from the brain biopsy tissue of several cases of SSPE. It appears that the measles virus is present in the brain as an incomplete virus with defective replication.

Treatment

Subacute sclerosing panencephalitis has no treatment or cure available at present. If it is diagnosed in stage 1 then it may be possible to manage the condition by intraventricular interferon alfa and oral isoprinosine, but the effect of these medications vary from patient to patient. Only supportive treatment is given in this disease.

Ayurvedic overview

In Ayurveda, we can correlate SSPE with two main factors, one of the factors is vitiation of tridosha that is vata, pitta and kapha along with pranvaha srotas dusti and another is aagantuj vyadhi because it is caused by measles virus. Vitiation of vata takes place from either wasting of dhatus or obstruction in passage. Vata, pitta and kapha move in all the channels of the body. Due to subtleness, vata itself provokes the other two doshas that are pitta and kapha. When aggravated it excites them and carrying them to different places produces different disorders due to obstruction in passage and dries up rasa etc. This produces symptoms of all three doshas in this disease.

Herbal remedies for SSPE by planet ayurveda

Planet Ayurveda provides different kinds of ayurvedic medicines for various kinds of diseases in which effective and natural herbs are used. They strictly follow all the principles of ayurveda which are described in ancient textbooks of ayurveda. All these medicines are GMP certified and vegetarian. These are safe to use and effective in the human body. There are no preservatives, chemicals, yeast etc. In this disease, no treatment is available at present. Only supportive treatment will be given. These herbal remedies can be considered for treatment of this disease until stage 2. These medicines will lead to delayed progression of this disease. The planet ayurveda provides herbal remedies for subacute sclerosing panencephalitis which are following

Product List

  1. Gandhak rasayan
  2. Neurogenie capsules
  3. Boswellia + Curcumin
  4. Gotu kola capsules
  5. Indian valeriana

Herbal Remedies for Subacute Sclerosing PanencephalitisBuy Now: Herbal Remedies for Subacute Sclerosing Panencephalitis

PRODUCT DESCRIPTION

1. Gandhak rasayan

It is a herbal tablet made from shuddha gandhak (purified sulphur). It is an antimicrobial, antibacterial, antipyretic, anti-allergic, anti-inflammatory antiviral and a broad spectrum antibiotic. It kills intestinal worms and is a good blood purifier. It contains various antioxidants. It is an immunity booster and indicated in infertility, debility, indigestion, breathlessness, abdominal pain. It detoxifies the blood, impurities, clears dirt and prevents secondary infection. It is very useful in urinary tract infection along with expelling the harmful pathogen from the body system.

DOSE:- 2 Tablet twice daily with lukewarm water

2. Neurogenie capsules

It is a polyherbal capsule made from brahmi (bacopa monnieri), ashwagandha (withania somnifera). It is bitter and astringent in taste and light and slightly hot in effect. It is a pacifier of all the three doshas (vata, pitta and kapha). It has a tonic effect on the brain and the nervous system. It possesses antioxidant properties, and also has the amazing ability to facilitate learning and enhance memory and concentration. It is a medicine that braces the mind to carry cognitive functions and intellectual pursuits. It is beneficial for maintaining all the three doshas, it counteracts the vitiated vata dosha-the factors which govern the nervous system. It is very good medicine for reducing the effects of stress and nervous anxiety.

DOSE:- 2 Capsules twice daily with plain water, after meals

3. Boswellia+Curcumin

It is a polyherbal capsule made from shallaki (Boswellia serrata) and haridra (curcuma longa). It is bitter and pungent in taste and dry, light and hot in effect. It alleviates kapha and vata. It has anti-inflammatory features which stops the cytokines secretion and reduces inflammation or swelling. It has an antioxidant property which protects brain neurons and reduces the wrinkles on skin. It purifies the blood and helps in blood formation in the body. It is used in various diseases like acne, blemishes, burns, auto-immune disorders and liver diseases. It also applies on cuts and bruises because it is a natural antibiotic. It prevents colon and skin tumors. It is known as antibacterial, anti-allergic, carminative and diuretic medicine. It is an effective remedy for sprains, wounds and inflamed joints.

DOSE:- 1 capsule twice daily, after meals with plain water.

4. Gotu kola capsules

It is a single herbal capsule containing gotu kola (centella asiatica). It is bitter and astringent in taste. It is light and mildly hot in effect. It has the ability to enhance memory and learning power. It is a tranquiliser, a muscle relaxant, an anticonvulsant, a blood purifier, an antipyretic, carminative and digestive agent. It balances all the three doshas-vata, pitta and kapha. It is useful in anxiety, depression, hypertension, sleeplessness, mental retardation, insanity and hysteria. It also helps maintain clarity of thoughts and is effective in age related mental disorders in old persons. It is indicated in anxiety, depression and nervous exhaustion.

DOSE:- 2 Capsules twice daily with plain water, after meals.

5. Indian valeriana

It is a single herbal capsule made from tagar (valeriana wallichii). It is pungent, bitter and astringent in taste. It is light, slimy and hot in effect. It balances all the three doshas- mainly vitiated kapha and vata dosha. It is a wound healer. It is indicated in indigestion, abdominal pain, enlargement of liver, arthritis, general debility, convulsion, hysteria, skin disease, fever, etc. It is a soothing and sedative action on the central nervous system. It is very effective in restlessness, palpitations and mild hypertension. Due to its sedative action it is very effective in chronic anxiety, depression, insomnia, migraine, and tension headaches.

DOSE:- 1 Capsule twice daily with plain water, after meals.

Contact Planet Ayurveda Support Team to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or Call at 0172-521-4030 (India), +91-172-521-4030 (Outside India) or Whatsapp at (+91) 9915-593-604

Conclusion

Subacute sclerosing panencephalitis is the neurological condition in which inflammation of the brain takes place. In ayurveda, we can correlate this disease with imbalance of tridosha that is vata, pitta and kapha and another reason is aagantuj vyadhi because it is caused by measles virus infection. There is no treatment as such for this disease but we can give supportive treatment to delay the progression of disease. We can use various kinds of herbs like shuddha gandhak, brahmi, ashwagandha, boswellia, curcumin, gotu kola etc which are very effective in inflammatory conditions as well as soothing the mind and enhancing the intellectual power. . Herbal medicines like gandhak rasayan, neurogenie capsules, indian valeriana etc are wonderful medicines for the management of SSPE until stage 2.