April 3, 2021
Yakrit Plihantak Churna Regulates TNF-Alpha & IL1-beta and Reduces Hepatic Inflammation
As the Ayurveda system of medicines is the oldest and natural medicinal system, a large number of chronic diseases can be treated with Ayurvedic medicines. Ayurvedic medicines are made up of natural herbs only which treat the root cause of the disease in a natural way without showing any side effects. From one of the dreadful disorders, hepatic inflammation is one and affecting a large portion of the population. But to treat this, Yakrit Plihantak churna is used and very positive results of this herbal remedy are observed. In this article, we will study about the disorder hepatic inflammation and how Yakrit Plihantak churna provides relief from this condition.
What Is Hepatic Inflammation?
Hepatic or Liver inflammation can be defined as the reaction occurring after attack by a disease-causing substance or microbes on liver cells. It affects the various digestive functions along with some other activities occurring in the liver and makes the patient uncomfortable due to inflammation. Major functions performed by the liver includes production of bile for converting food into energy, production of hormones, regulating fat storage, cholesterol generation, purifying the blood and excreting toxins from the body including alcohol and drugs. But due to hepatic inflammation, all these activities got disturbed.
The term “Hepatitis” is considered for inflammation of the liver. Most types of hepatitis occur from viral infection and sometimes by auto-immune disorders hat affect the body’s immune system which further begins to attack liver cells and cause inflammation in the liver.
Signs and symptoms observed in the patient of Hepatic inflammation include
- Yellowness of the eyes and skin
- Intermittent vomiting
- Pale stool color
- Dark urine color
- Itchy skin
- Swelling in the ankles and legs
- Pain and swelling in the abdominal area
What Is Tnf-Alpha?
TNF-alpha stands for Tumor necrosis factor-alpha. It is a cytokine or we can describe it as a small protein brought in use by the body’s immune system for passing signals through the cells. When an infection is detected by the macrophages (certain white blood cells), secretion of TNF is done to alert various other cells of the immune system and various tissues from being infected. This mechanism results in inflammation in the whole body.
When an infection or disease starts to develop in the liver cells, inflammation in the liver is done by TNF-alpha. This inflammation makes the patient troublesome in doing daily routine activities. TNF-alpha is a necessary body compound which protects the other body organs by alerting them but its way of working is found to be annoying to the body. Meanwhile, we can say that inflammation is considered as the good sign of the health of the immune system and shows that the body’s immune system is working wisely.
What Is Il 1-Beta?
IL 1-beta implies Interleukin 1-beta, also recognized as lymphocyte activating factor, mononuclear cell factor, leukocyte endogenous mediator or leukocytic pyrogen. Basically it is a cytokine protein which is encoded by IL1B gene in the human body. IL 1-beta is a part of the interleukin 1 family of cytokines. This cytokine is secreted by stimulated macrophages as a proprotein which further gets converted into an active state by caspase 1 (CASP1/ICE). This cytokine is considered as an essential mediator of the inflammatory response and plays an important role in multiple cellular functions such as cell proliferation, apoptosis and differentiation. This cytokine does the enhancement of COX-2 (cyclooxygenase-2) enzyme in the CNS (central nervous system) which contributes to inflammatory pain. When the infection begins to rise inside the liver cells, the IL 1-beta begins to protect cells and results in inflammation.
Yakrit Plihantak Churna By Planet Ayurveda
Yakrit Plihantak churna prepared by Planet Ayurveda is a well known herbal formulation for its positive impact on the liver and enhance its health. This churna reduces hepatic inflammation as well as treats a variety of diseases associated with the liver. Yakrit Plihantak churna detoxifies the liver and restores its health. Along with that, hepatic inflammation is managed and reduced by this churna which provides the relief to the patient.
This churna is processed with eight herbs obtained from the nature of God. Thus, we can say that one churna consists of the potency of eight herbs. All these herbs are used by extracting them through a standard procedure and only high quality extracts are used in preparing this churna under the guidance of expert Ayurvedic doctors who ensure this churna is 100 percent natural. No preservative, chemical, color, additive, binder, starch or any chemical material is utilized in this churna. Thus, no side-effect will be given to the patient who is consuming Yakrit Plihantak churna, whether he is a child, an adult or an elder. This churna is totally safe for consumption by any age grouped person.
Herbs present in Yakrit Plihantak churna work in a synergistic manner to reduce inflammation in the liver.
These Herbs are
- Bhumi Amla (Phyllanthus niruri)
- Katuki (Picrorhiza kurroa)
- Makoy (Solanum indicum)
- Punarnava (Boerhavia diffusa)
- Kalmegh (Andrographis paniculata)
- Kaasni (Cichorium intybus)
- Sharpunkha (Tephrosia purpurea)
- Bhringraj (Eclipta alba)
How Yakrit Plihantak Churna Reduces Hepatic Inflammation?
Yakrit plihantak churna is very beneficial in reducing hepatic inflammation due its properties possessed by various herbs present inside the churna. All these herbs are rich sources of various health beneficial properties that provide nourishment to the liver and treat the multiple diseases of the liver. The role of herbs in maintaining the health and reducing hepatic inflammation is as follows:
1. Bhumi Amla (Phyllanthus niruri)
Multiple medicinal properties are present in Bhumi Amla herb which makes it capable of managing various health issues. Hepatoprotective properties, antioxidant properties, antiviral properties, etc are present in this herb. It regulates the functioning of Tnf-alpha and IF-1 beta. Hence reduce the hepatic inflammation.
2. Katuki (Picrorhiza kurroa)
Active constituents present in the roots of Katuki are picrorrhizin (a bitter ingredient) 15 %, cathartic acid 9%, glucose and wax in small quantities. These chemical constituents improve the bilous flow and prevent the deposition of fat and bile inside the liver cells. It reduces the risk of liver disease and maintains its normal functioning.
3. Makoy (Solanum indicum)
Makoy herb used in the Yakrit Plihantak churna consists of diosgenin, epicatechin, solasonine, alpha, glycosides, rutin, naringenin, gallic acid, sapogenin, etc. These chemical constituents provide the property of antidiabetic, antibiotic, antiseptic, anti-inflammatory, diaphoretic, etc. Hepatic inflammation is reduced to a great extent by this herb.
4. Punarnava (Boerhavia diffusa)
Punarnava is a rich source of nutrients and bioactive substances which are beneficial for the overall health. Sodium, calcium, vitamin c, iron, oleanolic acid, hypoxanthine, boeravinone A to F, serratagenic acid, etc are found in this herb. Punarnava improves the body metabolism and improves the functioning of the liver.
5. Kalmegh (Andrographis paniculata)
The whole part of the Kalmegh herb contains chlorophyll and kalameghin in large quantities which is used to treat diseases developed through imbalance in Pitta and Kapha dosha. This herb is used as liver stimulant, digestion enhancer and in prevention of liver and spleen enlargement. Beyond this, Kalmegh improves blood metabolism, treats jaundice, constipation, diarrhea and enhances liver health. TNF alpha and IL 1-beta are successfully managed by this herb and hepatic inflammation is prevented.
6. Kaasni (Cichorium intybus)
Being a cholagogue, appetizer, and liver stimulant, Kaasni treats the health issues generated by impaired agni, liver dysfunctions, and jaundice. This herb is also used in general debility, pitta induced disorders, burning sensation and fever.
7. Sharpunkha (Tephrosia purpurea)
Sharpunkha herb’s nature is to optimise the secretion of bile and prevents the accumulation of fat as well as bile inside the liver cells which is the major cause of liver disease. The healthy condition of the liver is maintained by this herb due to its anti-toxic, diuretic and antipyretic properties.
8. Bhringraj (Eclipta alba)
Large quantities of resins and ecliptin are present in this herb. That is why it is processed in the Yakrit Plihantak churna. It is a strong liver stimulant, and shows its main action on the liver and the spleen. It provides protection to the liver and stimulates lipotropic activity which increases the cutdown of the fat and prevents its deposition in the liver. Thus, decrease the hepatic inflammation.
After reading and understanding this article, we can say that Yakrit Plihantak churna is an effective herbal remedy to overcome the disorders of liver and improve the life-span of the liver. This churna is totally natural and doesn’t possess any side-effects of the patient’s body.