Alternate to Tinidazole and metronidazole for Giardiasis

Abstract

Giardiasis is a protozoal infection. This disease affects our intestines. There are billions of bacteria in our intestines which are helpful to digest and absorb nutrients. But infectious bacteria or organisms cause infection in our gut. Giardiasis infection is caused by flagellate giardia intestinalis called giardia lamblia. This disease is spread through people to others. In this disease a person is having diarrhea, vomiting, abdominal cramps, bloating, loss of appetite, lethargy, abdominal tenderness and distension. The treatment of choice in Allopathy is tinidazole and metronidazole. So in this article we are going to discuss tinidazole and metronidazole along with effective Ayurvedic medicines in detail.

Giardiasis

What is Tinidazole and Metronidazole?

These drugs come under the class of antiamoebic and antiprotozoal drugs. These drugs are useful in infection which is caused by a protozoa Entamoeba histolytica. These two drugs are the prototype of nitroimidazole which was introduced in 1959 for trichomoniasis. But later on it is found that it is a highly active amoebicide. Metronidazole and Tinidazole have broad-spectrum cidal activity against anaerobic protozoa. But they do not affect aerobic bacteria. They are selectively toxic to anaerobic and microaerophilic microorganisms. After entering into the bacterial cell by diffusion, the nitro radical of these drugs reduced the activity of the bacteria. This nitro radical exerts cytotoxicity (probably by damaging DNA). In addition metronidazole and tinidazole have been found to inhibit the cell mediated immunity which induce mutagenesis and thus further cause radio sensitization. These both drugs are used in intestinal as well as extra intestinal infections also.

Pharmacokinetics

Metronidazole and Tinidazole are almost completely absorbed from small intestines. Little unabsorbed drugs reach the colon. Metabolism occurs in the liver by oxidation and glucuronide conjugation. Plasma t1/2 of metronidazole is 8 hours.

Adverse effects

Adverse effects of these two drugs are relatively frequent and unpleasant. The side effects of these two drugs are

  • Anorexia, Nausea, Metallic taste, abdominal cramps, loose stool are the most common side effects.
  • Headache, glossitis, dryness of mouth, and dizziness are the less frequent side effects.
  • Prolonged use of these drugs causes peripheral neuropathy and CNS effect.

Contraindications

It is contraindicated in the following

  • Neurological disease
  • Blood dyscrasias
  • First trimester of pregnancy

Uses of Metronidazole and Tinidazole

These are useful in

  • Amoebiasis
  • Giardiasis
  • Trichomonas vaginitis
  • Anaerobic bacterial infections
  • Helicobacter pylori gastritis

Dosage

  • Metronidazole- 400 mg TDS
  • Tinidazole- 0.6 gm

Difference between Metronidazole and Tinidazole

Tinidazole is mainly equally effective congener of metronidazole, but some little difference is there

  • Its plasma t1/2 is 12 hour
  • Duration of action is longer than metronidazole
  • It is more suited in single dose

Because of the adverse effects of these medicines, we are introducing some safe and herbal products for the treatment of giardiasis

Herbal Products for Giardiasis

Planet Ayurveda offers the best herbal products for the treatment of giardiasis. This is a manufacturing company which manufactures various herbal products and these herbal products are made using the standardized extracts of potential herbs. Also these are made under expert advice.

Herbal-products-for-giardiasis

Herbs for Giardiasis

This company offers following herbal products for giardiasis

  1. Sanjivani Vati
  2. Mahashankh Vati
  3. Wormistop Capsules

Product description

1. Sanjivani Vati

This is a classical Ayurvedic formulation. It is a natural source of life and health. this vati contains very potent herbs like- sonth (Zingiber officinale), harar (Terminalia chebula), bahera (Terminalia bellerica), amla (Emblica officinalis), vidanga (Embelia ribes), giloy (Tinospora cordifolia), shuddha Bhallataka (Purified Semecarpus anacardium) etc. It has antipyretic and diaphoretic properties. It is also known as the best Aama (endotoxins) digestive. It also helps in maintaining the metabolism.

Dosage: 1 tablet twice a day after meals with plain water

2. Mahashankh Vati

This is also a classical ayurvedic medicine. This is a natural solution for abdominal pain, acidity and indigestion. This Ayurvedic formulation contains chitrak (Plumbago zeylanica), danti (Baliospermum montanum), sajjikshara (natural sodium carbonate) etc. this herbal product of planet ayurveda is best for digestive disorders such as indigestion, abdominal pain, disturbed bowel movement, loss of appetite etc. It has anti-inflammatory and anti-helminthic properties.

Dosage: 1 tablet twice a day after meals with plain water

3. Wormistop Capsules

These are poly herbal formulations of Planet Ayurveda. This formulation is helpful in managing infectious diseases like giardiasis. These capsules are made using the standardized extracts of palaash (Butea monosperma), tulsi (Ocimum sanctum), vidanga (Embelia ribes), sonth (Zingiber officinale). These ingredients are very effective for treating digestive problems. It is helpful in alleviating the digestive symptoms like indigestion, bloating, pain, excessive hunger etc.

Dosage: 1 capsule twice a day after meals with plain water

Conclusion

As we saw that allopathic medicines have drastic side effects. They are helpful in treating giardiasis but left with side effects in the body. So it’s better to take Ayurvedic medicines for better results. Moreover, these ayurvedic medicines are left with no side effects and treat the disease from its root cause. So one should use herbal products of Planet Ayurveda and enjoy a happy and healthy life.

Dr. Vikram Chauhan

https://www.planetayurveda.com

DR. Vikram Chauhan, MD - AYURVEDA is an expert ayurvedic doctor based in Chandigarh, India and doing his practice in Mohali, India. He is spreading the knowledge of Ayurveda - Ancient healing treatment, not only in India but also abroad. He is the CEO and Founder of Planet Ayurveda Products, Planet Ayurveda Clinic and Krishna Herbal Company. Write at - herbalremedies123@yahoo.com, Contact at - +91-172-521-4030 Websites - www.planetayurveda.com, www.alwaysayurveda.com

View more posts from this author

Leave a Reply

Your email address will not be published. Required fields are marked *

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <s> <strike> <strong>