Ayurvedic View On Crigler Najjar Syndrome & Its Treatment


It is a very hard situation where a child is born with congenital defects. No one except the parents of the child can understand the pain that child goes through because of these congenital diseases. Medical science has evolved so much in the last few decades, but still there are some limitations that make it helpless in some cases. Today in our topic we are going to learn about one such disease, where a newborn has some congenital defects, that is Crigler Najjar syndrome.

Crigler Najjar Syndrome

Introduction Of Crigler Najjar Syndrome

Crigler najjar syndrome is a clinical condition which is characterized by severe unconjugated hyperbilirubinemia (convert and clear bilirubin from the body). This is so called as first described by Crigler and Najjar in 1952. It is a rare autosomal recessive disorder. This could result in bilirubin induced neurological disorder. There are broadly two types of Crigler Najjar Syndrome which are as follows:

Type 1 crigler najjar syndrome: This type of crigler najjar syndrome includes absence or minimal bilirubin-UGT1A1 activity. It starts in the neonatal stage that is right after birth till whole life. Patients with this type of crigler najjar syndrome are more prone to develop BIND (Bilirubin Induced Neurological Disorder). This is managed with daily phototherapy in order to maintain serum bilirubin in normal limits. This is the severe type of crigler najjar syndrome.

Type 2 crigler najjar syndrome: This is a less severe type of crigler najjar syndrome as it has reduced bilirubin-UGT1A1 activity.

Causes Of Crigler Najjar Syndrome

This happens because of a mutation in a gene that is known as the UGT1A1 gene. Genes are responsible for the manufacturing of the proteins which play important roles in the body. When there is an alteration or mutation in genes then the information for the production of proteins might be faulty. Therefore, in this case the mutation of UGT1A1 gene which hinders the proper conversion and excretion from the body.

Symptoms Of Crigler Najjar Syndrome

The symptoms of Crigler najjar syndrome are as follows:

  • Jaundice in neonates
  • Bilirubin encephalopathy also known as Kernicterus (A condition in which bilirubin gets accumulated in the brain, damaging the central nervous system)
  • Vomiting
  • Fever
  • Unsatisfactory feeding
  • Opisthotonus (a kind of posture due to spasms of the muscles which result in bending of heels and head backwards and body bows forward)

Diagnosis Of Crigler Najjar Syndrome

The diagnosis of the Crigler Najjar Syndrome is done with the help of genetic testing. This is a special technique and not available at every laboratory.

Treatment in Allopathy For Crigler Najjar Syndrome

Unfortunately, there is only management possible in allopathy which means with the help of aggressive phototherapy the unconjugated bilirubin is excreted through bile. In short, the scope of the treatment in allopathy for Crigler Najjar Syndrome is not promising.

Ayurvedic point of view On Crigler Najjar Syndrome

When we come across terms like mutation and genes then it seems that they have been discovered recently a century ago with the aid of a microscope. But this is not the case in Ayurveda. Even thousands of years before the discovery of the microscope Ayurveda gave descriptions of genes in ancient texts. Genes are referred to as “Beejbhaga” and chromosomes are referred to as “Beej” and parts of chromosomes as “beejabhagavayava”. Any abnormality (mutation) in the Beej Bhaga leads to genetic disorders like in this case of Crigler Najjar syndrome.

Planet Ayurveda is a leading firm which prepares natural herbs using authentic ways and has great results in curing Crigler najjar syndrome. All the herbs that are prepared here are free from chemicals, preservatives, starch, additives, colors, yeast, binders and fillers. They are 100 percent natural and are formulated by MD Ayurvedic doctors with years of experience. It has a worldwide range of distributors and has a great response from various countries when it comes to cure diseases that are considered incurable by allopathic doctors.

Products available at Planet Ayurveda for Crigler Najjar Syndrome

  1. Yakrit Plihantak Churna
  2. Phyllanthus Niruri
  3. Echinacea Capsules
  4. Liver Detox Formula

Herbal Remedies For Crigler Najjar Syndrome

1. Yakrit Plihantak Churna

It is a wonderful remedy for clearing the toxins from the body by supporting the liver. A very useful formulation by Planet Ayurveda for cirrhosis liver, fatty liver, jaundice which is because of damage caused by alcoholism. In the Crigler Najjar syndrome it is like a blessing as it promotes bile production and excretion. Ingredients of the Yakrit Plihantak Churna are Bhumi Amla (Phyllanthus niruri), Bhringraj (Eclipta alba), Kaasni (Cichorium intybus), Makoy (Solanum indicum), Kalmegh (Andrographis paniculata) and other herbs.

Dosage: You can boil the powder 1 teaspoonful in 400 ml water, keep it boiling until it remains 50 ml. Strain it and drink the water. Leave the residue. Do it twice daily. Make fresh every time.

2. Phyllanthus Niruri

This formulation of Planet Ayurveda is a great appetite stimulant. It will be helpful in all cases of Hepatitis of any type. In the malfunctioning of the liver it is a well indicated remedy. For fatty liver, hepatitis, liver enlargement and other liver disorders this formulation is inevitable. Its anti-hepatotoxic property makes it a favorite remedy to be recommended by physicians in cases of diseased liver for better functioning. Ingredients of Phyllanthus Niruri are Bhumi Amla (Chanca piedra).

Dosage: 2 capsules twice daily after meals with warm water.

3. Echinacea Capsules

For ones who have low immunity and catch cold easily, this is a permanent solution. The Indian Echinacea is also known as “king of Bitters”. It works well in cases of parasitic infections, viral infections and bacterial infection. Very useful in skin affections also. Ingredients of the Echinacea Capsules are Kalmegh (Andrographis paniculata).

Dosage: 2 capsules twice daily after meals with warm water.

4. Liver Detox Formula

It is an inevitable formulation for the detoxification of the liver. It will support the functions of the liver and increase the appetite. Apart from liver detoxification it has many other benefits like better control of blood sugar in a natural way. The long effects of the drug abuse could be easily eliminated with the help of this marvelous formulation of Planet Ayurveda. Ingredients of the Liver Detox Formula Capsules are Makoy (Solanum nigrum), Jhavuka (Tamarix gallica), Haritaki (Terminalia chebula), Punarnava (Boerhavia diffusa), Katuki (Picrorhiza kurroa) and other herbs.

Dosage: 2 capsules twice daily after meals with warm water.


We could conclude that there are several herbs mentioned in the ancient texts of Ayurveda which are capable of curing the Crigler Najjar Syndrome. For cases which seem incurable in modern science, Ayurveda has a permanent cure. At Planet Ayurveda the formulations are prepared strictly following the principles of ancient Ayurveda. This helps in getting good results in curing chronic diseases.

Dr. Vikram Chauhan


Dr. Vikram Chauhan (MD - Ayurveda) is the CEO and Founder of Planet Ayurveda Pvt. Ltd. He is Author of the Book "Ayurveda – God’s Manual For Healing". He is an Ayurveda Expert Serving People worldwide through all the Possible Mediums, Operating from Main Branch in Mohali, India. With his Vast Experience in Herbs and their Applied Uses, he is successfully treating Numerous Patients suffering from Various Ailments with the help of Purest Herbal Supplements, Diet, and Lifestyle, according to the Principles of Ayurveda. For More Details, visit www.PlanetAyurveda.com.

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